If SSS thrombosis pressure>ccsvi pressure, why...
Posted: Thu May 16, 2013 4:02 pm
Why don't people with SSS thrombosis have the same (or worse) MSy symptoms and MRI lesions?
http://dura.stanford.edu/Articles/Stam_NEJM05.pdf
It seems like they have very few brain stem related symptoms. I guess if the pressure is so great that it must be treated immediately, that would explain the lack of lesions. There isn't enough time for them to develop. Reflux might not be an issue too. But it seems like they should have cranial nerve dysfunction (questionable assumption?) from increased csf volume/pressure like MSers with ccsvi.
Could there be an anatomical difference making csf pressure greater in brain stem area of people with ms? Doesn't seem like something like that would be missed. But what else could explain the difference in symptoms? Maybe csf pressure isn't such a big deal in ms ccsviers?
Also interesting in that paper is the list of causes of SSS thrombosis, including birth control pills, pregnancy and childbirth, and infection.
(Female to male ratio for SSS thrombosis has followed the course of the ms ratio)
http://dura.stanford.edu/Articles/Stam_NEJM05.pdf
It seems like they have very few brain stem related symptoms. I guess if the pressure is so great that it must be treated immediately, that would explain the lack of lesions. There isn't enough time for them to develop. Reflux might not be an issue too. But it seems like they should have cranial nerve dysfunction (questionable assumption?) from increased csf volume/pressure like MSers with ccsvi.
Could there be an anatomical difference making csf pressure greater in brain stem area of people with ms? Doesn't seem like something like that would be missed. But what else could explain the difference in symptoms? Maybe csf pressure isn't such a big deal in ms ccsviers?
Also interesting in that paper is the list of causes of SSS thrombosis, including birth control pills, pregnancy and childbirth, and infection.
(Female to male ratio for SSS thrombosis has followed the course of the ms ratio)