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The following is a half baked idea that I thought I'd share.

Personally, I find that working out improves my physical abilities, and along these lines, I have used "pre-workouts" that contain caffeine to help me work-out longer. Which has also had me come across products that muscle builders use to "pump up" their blood supply to their muscles by increasing blood NO content. This observation triggered a thought, that maybe just maybe, it could also improve CCSVI flow, since people here have also talked of increasing blood content of NO.

One of the problems I have found, is that most also include artificial sweeteners (sucralose apparently being the favorite), which I personally consider a big no-no (that's lowercase...) and also has the propensity to act as a mild laxative in me

So, where I am going with this is, I would love to see if one of these "NO boosting proprietary blends" have any effect on CCSVI And would love to see a Doppler for CCSVI before and after taking one of these; on an MS patient.

Please note, I am not suggesting anyone try these, but an example of one of the many products in this category are: http://www.evogennutrition.com/evp.php

What Does EVP Do? wrote:The specialized ingredients in EVP result in a flood of enriching, blood-engorging nutrients into the muscle cell, causing an incredible increase in blood volume with a corresponding “swelling” of muscle tissues. EVP synergistically combines powerful proven, performance-boosting ingredients to deliver dramatic muscle-cell volumizing and fascia-stretching pumps. Within 20 minutes of consumption, your muscles will be maximally engorged with vein-popping, nutrient-rich blood.

Remember, its all advertising hyperbola, and the product includes sucralose.

Its a half baked idea I thought I'd share, but I would like opinions even, actually, especially if negative or critical.

Does this NO-boosting proprietary blend actually work, to any significant degree? You can't tell me, without compromising its propriety. If it works, does it actually boost storage or release of NO (like sunshine does)? From its description, it sounds like it would also work for erectile dysfunction. Lastly, ED drugs, and anything which chemically opens blood vessels, could systemically lower blood pressure, which is why you should not combine ED drugs with nitro-glycerine sprays, used to combat angina, (or tranquilizers, like the ones they use to sedate you during angioplasty, or pot??), because you may commit unintentional suicide, and that might ruin your night's fun. Other than that, I am no doctor, so don't listen to me. Seek the advice of someone who could be liable if you die following it.

Hey Cure--
the link you provided was pretty pumped-up and entertaining. (Anyone else remember Hans and Franz from SNL?? (!!!!)
I agree with you, it would be interesting to see before and after dopplers of people after ingesting NO inducing supplements--or maybe before and after 15 minutes on a treadmill.

Dr. Fox did a before and after hydration doppler study, which just improved blood volume, and that make a pretty big difference in CCSVI.
http://www.ncbi.nlm.nih.gov/pubmed/24175155

I'm sure there will be all kinds of studies like these in the future. But in the meantime, you're doing yourself a world of good by working out. Just don't spend too much money on the Hans and Franz stuff
cheer

I saw the fine print for this supplement. If it is what I think it is (EPO), it is what they gave my mother for her vasculitis, before she lost her kidneys. It is also what Lance Armstrong took after feeling it's effects when he had cancer. It works by actually increasing your blood cells.

If so,none of my comments about blood pressure apply. Shouldn't decrease it, would think the opposite. In its usual form it is a drug.

Your Mileage may vary.

its not EPO. From my understanding EPO is associated with blood doping, not oral ingestion. The advertisers may be attempting to provide the possible purchaser the feeling that it performs the same function, but that is just advertising, worded to mislead people.

Even if it was (which it is not) as I said, there are MANY products that purport to perform this function of increasing NO in blood sold as pre-workouts. The link I provided was purely as an example of these products not as a "best of". For example a search in Google returns over 2.5M hits https://www.google.com/search?q=NO+boost+pre+workout

OK but then warnings about drug combinations do apply. Careful when mixing vasodilators. I've had the heart and angina attacks. and I found it to be a miserable experience.

If you do expect to prove things to scientists you will need measurable repeatable tests and chemistry.

But if you do provide these things, the substances might show value. As I said, I am not qualified except by anecdotal experiences. If you don't combine it with the things I mentioned (nitroglycerine, ED drugs, tranquilizers, pot) you might not have any low BP experiences. The most powerful of all these is nitroglycerine. Maybe it affects the NO pathway, I don't know.

I had a doctor give me a test dose of nitroglycerin a while back when I was experiencing shortness of breath and chest cramps. I found that I felt clear headed and was surprisingly talkative. I kept going on and on about my research in grad school. I never did find out what the doctor thought of all of that. Oh, there wasn't much change in my chest cramps, but it was nice having a clear head for a bit.