Welcome to This is MS, the leading forum for Multiple Sclerosis research and support. Join our friendly community of patients, caregivers, and researchers celebrating over 20 years of delivering hope through knowledge.
https://www.thisisms.com/forum/
Well here's another person in the "ischemic changes cause immune activation and clean up" camp....Multiple sclerosis is ischemic damages first, from impaired blood flow, from MASS and de-railed electrostatics of fluid dynamics in human blood. This is also Guillain Barre syndrome. The myelin sheaths around the nerve cables can be damaged by antibodies against myelin basic protein, or other theories like “molecular mimicry.” The bottom line is that the ischemic conditions are coming first. When this is perpetual, waxing an waning, the damages will slowly accumulate, The “cables” of white matter tracts in the grain are also vascular. Even blood vessels have blood vessels (the vasa vasorum) and the white matters tracts, targeted in multiple sclerosis, will be targeted for autoimmune destruction of they are experiencing on-going damages from ischemia. This is achieved with repeat vaccinations, “sludged blood flow”, “MASS”, and derailed fluid dynamics in the microcirculation, brain, body, and the interconnecting tracts of the nervous system.