This Is MS Multiple Sclerosis Knowledge & Support Community

I noticed in the weekly listings I get emailed to me from National Center for Biotechnology Information (NCBI) at the U.S. National Library of Medicine (NLM), that PubMed.gov list Dr. Zamboni's papers. For example, this week's what's new list included:

The severity of chronic cerebrospinal venous insufficiency in patients with multiple sclerosis is related to altered cerebrospinal fluid dynamics.
Zamboni P, Menegatti E, Weinstock-Guttman B, Schirda C, Cox JL, Malagoni AM, Hojanacki D, Kennedy C, Carl E, Dwyer MG, Bergsland N, Galeotti R, Hussein S, Bartolomei I, Salvi F, Zivadinov R.
Funct Neurol. 2009 Jul-Sep;24(3):133-8.
PMID: 20018140 [PubMed - in process].

A way to indicate to doctors and others that the papers aren't just appearing from the blogoshere.

I like this new paper and will be excited to read the whole thing. We knew that some of Dr Zamboni's patients were being followed at JNI, wobbly is one of them.

There are at least 2 treatment groups, the liberation group which was reported on recently which included 18 month results on 65 patients; 35 RRMS, 20 SPMS, 10 PPMS.

The second treatment group wobbly is in was being followed at JNI with their 3T MRI. It was a small American contingent that was operated on in Italy then followed at JNI. I wonder if there is yet another treated group being followed?

THIS is the kind of data that will make the case:

Compared with the HCs, the CCSVI-MS patients showed a significantly lower net CSF flow (p=0.027) which was highly associated with the VHISS (r=0.8280, r2=0.6855; p=0.0001). This study demonstrates that venous outflow disturbances in the form of CCSVI significantly impact on CSF pathophysiology in patients with MS

the abstract basically says that the worse the CCSVI anomalous blood flow (they did the doppler tests and scored the flow) the greater the abnormality of cerebrospinal fluid flow dynamics.

Good work prairie !!

ozarkcanoer

For anyone who is interested in using PubMed to find papers mentioning MS through the U.S. National Center for Biomedical Information all you have to do is to formulate a search, like for 'multiple sclerosis' and save the search in your own "My NCBI". You can specify settings to have the search updates mailed to you daily, weekly or monthly. Each update will have a paper's title, authors and a link to the abstract and further information. Some papers have the full text available, some require access to publishers' websites.

Use the link to PubMed to go directly to the PubMed Help/FAQ/Quick Start web page.

Thanks a bunch for the assist prairie, we need eyes and ears everywhere!

Mark