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Rebif and Alpha Liopic Acid
Posted: Thu Dec 30, 2004 10:18 am
by Chicano
Friends,
A new member to the this great site. I am a 34 year old male living in San Francisco, CA, dx three years ago with rr ms. My doctor says I am stable with Rebif, notwithstanding the constant mild numbness and tingling in the legs, arms, and face.
I am interested in taking supplements as well, namely alpha liopic acid. People seem to speak highly of this supplement, although, I am concerned about it acting counter to the Rebif.
Any thoughts would be greatly appreciated. Thank you.
Posted: Mon Jan 03, 2005 5:21 pm
by Shayk
Hi Chicano and welcome to the site.
I have been on Avonex a little over a year and taking alpha lipoic acid for about 9 months at 1200 mg/day. I personally think it does wonders for the numbness, burning and tingling.
This site has some detailed scientific information about ALA, but doesn't address MS or the interferons.
I have no idea if it would act counter to the Rebif or the Avonex. I seriously doubt if there's information about this, but we could ask our neuros I guess.
Nice to hear you're doing well.
Sharon
Re: Rebif and Alpha Liopic Acid
Posted: Tue Jan 04, 2005 12:02 am
by NHE
Chicano wrote:I am interested in taking supplements as well, namely alpha liopic acid. People seem to speak highly of this supplement, although, I am concerned about it acting counter to the Rebif.
I don't know for certain, but I don't think that Lipoic Acid will counter act the effects of Rebif. Lipoic Acid inhibits NF-kB which is a transcription factor responsible for producing several proinflammatory cell signaling proteins. By inhibiting NF-kB, supplementation with Lipoic Acid should result in less overall inflammation in the body.
Here are some links for further reading...
In addition, I've been on Avonex for about 4½ years and have been taking R-Lipoic Acid supplements for about a year. I have not discussed this with my neurologist yet, however my MS symptoms have been stable for at least 3 to 3½ years.
I should note here, as I have in other threads, that I take other supplements as well.
NHE
Posted: Wed Jan 05, 2005 1:57 am
by Arron
welcome to the site. As pointed out above, Alpha Lipoic Acid has been discussed in a few studies as potentially beneficial for MS.