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I am torn. My left leg is weaker than my right and always have been. I have been working out faithfully and it remains the same. Although both legs are getting stronger, the left will never catch up to the right. This weakness causes a discernible limp and left legs tires more quickly. Last year my neuro gave me a prescription for Ampyra and it was my choice as to whether I wanted to start or not. He said I would know in a couple of weeks if it helps or not. I never started it. I have read from several patients that they believed that Ampyra caused worsening of their walking so I was too afraid to give it a try. Well, I am still debating. I don't think my walking is any worse than last year. But sometimes I think I should give it a try. I have 2 bottles of Ampyra that I received from the manufacturer last year so I have plenty to give it a trial. But I certainly don't want to worsen things! Advice and comments are welcome!!

my wife did the free one month trial. did not notice any positive affect during the month.

after stopping, her walking got a bit worse. maybe it was the normal ups and downs of MS or maybe it was the Ampyra.

if you are able to remain the same using diet and exercise, i think you should stick with that for now. just my opinion.

(BTW - make sure the Ampyra is still good. not sure if a year is too long or not. we were told 6 months is okay)

Thanks Doug. You just reaffirmed what I was thinking.

4-AP is not stable, and all the packaging of Ampyra confirms this to be the case. A 1 year old case is not what I would base any decision on anyway.