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Author Message
  Topic: To Copaxone or not to Copaxone
dreddk

Replies: 8
Views: 694

PostForum: General Discussion   Posted: Sun Jul 13, 2008 10:15 pm   Subject: To Copaxone or not to Copaxone
Thanks everyone for their comments. Very Happy I am a bit of a information junkie so really appreciate the references to studies and personal experience. My feeling now is that we will go down the Copaxone r ...
  Topic: Copaxone 40mg
dreddk

Replies: 3
Views: 450

PostForum: Drug Pipeline   Posted: Tue Jul 08, 2008 11:29 pm   Subject: Copaxone 40mg
Looks like they were hoping to use the data to extend their patent protection

"...analysts said the company planned to use the larger dose to extend the Copaxone franchise after the original drug l ...
  Topic: To Copaxone or not to Copaxone
dreddk

Replies: 8
Views: 694

PostForum: General Discussion   Posted: Wed Jul 02, 2008 4:10 pm   Subject: To Copaxone or not to Copaxone
Hi All,

My 33 year old wife is facing a decision on Copaxone and I'd be interested in people's feedback. Smile

Bit of background - she had her first Optic Neuritis 11 years ago and subsequently ha ...
  Topic: Interferon and atorvastatin may increase disease activity
dreddk

Replies: 0
Views: 218

PostForum: Statins   Posted: Sun Jun 22, 2008 5:42 pm   Subject: Interferon and atorvastatin may increase disease activity
The combination of 40 or 80 mg atorvastatin with thrice weekly, 44 mcg interferon beta-1a in persons with multiple sclerosis resulted in increased MRI and clinical disease activity. Caution is suggest ...
  Topic: Efficacy of Disease-Modifying Therapies Review Study
dreddk

Replies: 20
Views: 1875

PostForum: Tysabri (Antegren or Natalizumab)   Posted: Fri May 23, 2008 3:24 pm   Subject: Efficacy of Disease-Modifying Therapies Review Study
Of course drug companies love pointing to lesions as its so easy to measure even if the correlation with disability progression is quite loose.

It is quite mindblowing the money being spent on drug ...
  Topic: Efficacy of Disease-Modifying Therapies Review Study
dreddk

Replies: 20
Views: 1875

PostForum: Tysabri (Antegren or Natalizumab)   Posted: Thu May 08, 2008 3:45 pm   Subject: Rebif vs Tysabri
It's interesting because in the study I quoted, they talk about Rebif versus Tysabri.

The Tysabri study showed a substantially better effect compared to the Placebo group when compared against Reb ...
  Topic: Efficacy of Disease-Modifying Therapies Review Study
dreddk

Replies: 20
Views: 1875

PostForum: Tysabri (Antegren or Natalizumab)   Posted: Fri May 02, 2008 4:55 pm   Subject: Efficacy of Disease-Modifying Therapies Review Study
From the study conclusion:

"Of the available agents, Tysabri and high-dose,
high-frequency IFNs (Betaseron and Rebif) appear to be
significantly more effective than placebo...Both Avonex and Copa ...
  Topic: Efficacy of Disease-Modifying Therapies Review Study
dreddk

Replies: 20
Views: 1875

PostForum: Tysabri (Antegren or Natalizumab)   Posted: Thu May 01, 2008 4:35 pm   Subject: Efficacy of Disease-Modifying Therapies Review Study
Our objective was to compare the clinical efficacy of currently approved first-line DMTs in patients with RRMS, applying an evidence-based medicine approach. We reviewed all phase III pivotal trials o ...
  Topic: Little son - how do I minimise his risk?
dreddk

Replies: 5
Views: 493

PostForum: General Discussion   Posted: Tue Apr 29, 2008 8:08 pm   Subject: vitamin d3 supplement
I give my one year old daugher this vitamin d3 supplement
http://www.meadjohnson.ca/en/products/vitamins_1.html

My 3-year old give the life extension 1,000iu as its a very small pill and easy for ...
  Topic: CoreControl Cooling Glove
dreddk

Replies: 2
Views: 293

PostForum: General Discussion   Posted: Thu Sep 13, 2007 1:06 am   Subject: CoreControl Cooling Glove
I understand they are working on one for release late this year, early 2008. It's significantly more effective than cooling vests etc for lowering your core temperature so would be great to see the co ...
  Topic: CoreControl Cooling Glove
dreddk

Replies: 2
Views: 293

PostForum: General Discussion   Posted: Wed Sep 12, 2007 3:58 pm   Subject: CoreControl Cooling Glove
Newish cooling glove that uses the hand's natural radiators to cool the bodys inner core. Case study on use with people with MS.

http://www.avacore.com/pdfs/CoreControl-Human-Studies.pdf

My comp ...
  Topic: Anyone else on FTY720?
dreddk

Replies: 10
Views: 1745

PostForum: Drug Pipeline   Posted: Sun Jul 22, 2007 5:42 pm   Subject: Blog of someone in the trial
Not sure if anyones seen this blog but its Johan, who has been in the FTY 720 trial, and has seen some pretty dramatic improvements (EDSS 5.5 to 2.0 on the trial)
Very Happy
http://blogger.xs4all.nl/jschu ...
  Topic: Pipex
dreddk

Replies: 10
Views: 1036

PostForum: Drug Pipeline   Posted: Wed Jul 18, 2007 7:41 pm   Subject: Pipex
Interestingly the Cochran Review of interferons found in its review of all studies "If interferon-treated participants who dropped out were deemed to have progressed (worst case scenario) the signific ...
  Topic: Vitamin D3 Supplement - Children
dreddk

Replies: 7
Views: 1153

PostForum: Natural Approach   Posted: Wed Mar 07, 2007 3:21 pm   Subject: Vitamin D3 Supplement - Children
Hi Nick,
If you don't mind me asking, what cod liver oil are you giving your youngest? I've ordered the carlsons cod liver oil lemon flavored. The recommended dosage I have seen works out at 1 teaspo ...
  Topic: Vitamin D3 Supplement - Children
dreddk

Replies: 7
Views: 1153

PostForum: Natural Approach   Posted: Tue Feb 27, 2007 2:57 pm   Subject: Vitamin D3 Supplement - Children
That's interesting thanks - I see in the large study of nurses that 400IU seemed to offer some benefit but then several other studies I have read suggest that around the 800IU or greater is needed to ...
 
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