| Author |
Message |
Topic: TREM-2 "in the wrong place" |
rainer
Replies: 1
Views: 184
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Forum: General Discussion Posted: Sat Oct 04, 2008 12:18 am Subject: TREM-2 "in the wrong place" |
[url=http://medicine.plosjournals.org/perlserv/?request=get-document&doi=10.1371/journal.pmed.0040124&ct=1]Here is one of the mouse studies.
TREM2-Transduced Myeloid Precursors Mediate Nerv ... |
Topic: Hypercoagulation |
rainer
Replies: 28
Views: 694
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Forum: General Discussion Posted: Fri Oct 03, 2008 7:27 pm Subject: Hypercoagulation |
Here is another article on this topic. A little easier to read then the last one I posted, and has some nice diagrams.
[url=http://molinterv.aspetjournals.org/cgi/content/full/4/3/163?maxtoshow=&a ... |
Topic: Hypercoagulation |
rainer
Replies: 28
Views: 694
|
Forum: General Discussion Posted: Thu Oct 02, 2008 11:33 pm Subject: Hypercoagulation |
Impaired fibrinolysis in multiple sclerosis: a role for tissue plasminogen activator inhibitors
Full article is here: http://brain.oxfordjournals.org/cgi/content/full/126/7/1590
I am going to h ... |
Topic: Hypercoagulation |
rainer
Replies: 28
Views: 694
|
Forum: General Discussion Posted: Mon Sep 29, 2008 4:46 pm Subject: Hypercoagulation |
| hey cheer - I know you are big into the supps.... have you looked up any of the fibrin-reducing enzymes? I have no idea if they work but fibrin (which helps blood coagulate) also increases inflammati ... |
Topic: ASCT does not erase immune-markers in CSF |
rainer
Replies: 9
Views: 613
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Forum: Revimmune (cyclophosphamide or cytoxan) Posted: Thu Sep 25, 2008 4:53 pm Subject: ASCT does not erase immune-markers in CSF |
My philosophy is find out it if it works then work out the kinks.
Maybe reinfusing pre-collected stem cells could do that, although it seems like there would be no difference between the stems cell ... |
Topic: Macarthur Foundation fellow |
rainer
Replies: 0
Views: 119
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Forum: Stem Cells Posted: Wed Sep 24, 2008 4:42 pm Subject: Macarthur Foundation fellow |
One of the winners of a Macarthur grant is doing some interesting work with neural stem cells.
http://www.macfound.org/site/c.lkLXJ8MQKrH/b.4537291/
Sally Temple is a developmental neuroscientis ... |
Topic: ASCT does not erase immune-markers in CSF |
rainer
Replies: 9
Views: 613
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Forum: Revimmune (cyclophosphamide or cytoxan) Posted: Wed Sep 24, 2008 4:37 pm Subject: ASCT does not erase immune-markers in CSF |
| I wonder if by giving them an autologous transfusion of stem-cells you may actually be jump-starting the MS process back in a way that just immunoablation avoids. Maybe an allogenic transplant would ... |
Topic: ASCT does not erase immune-markers in CSF |
rainer
Replies: 9
Views: 613
|
Forum: Revimmune (cyclophosphamide or cytoxan) Posted: Tue Sep 23, 2008 10:31 pm Subject: ASCT does not erase immune-markers in CSF |
| What stage or type of MS did the patients they pooled their own with? Did those patients receive the exact same immunoablative protocol? Was this a blind study? Why no mention that MS patients who ... |
Topic: Opinions on clinical trial |
rainer
Replies: 10
Views: 352
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Forum: General Discussion Posted: Sat Sep 20, 2008 5:07 pm Subject: Opinions on clinical trial |
I would take the combination study. Non-placebo trials are still somewhat rare.
8 shots sounds worse then 3 obviously but you're body may react otherwise. And if the study is too rough on you, fi ... |
Topic: Accelerated Cure Project Benefit |
rainer
Replies: 6
Views: 377
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Forum: Tovaxin Posted: Sat Sep 20, 2008 1:17 pm Subject: Accelerated Cure Project Benefit |
i've seen the handsome family, they are very cool  |
Topic: Opexa Announces Top-Line Results from Phase IIb Trial |
rainer
Replies: 67
Views: 2851
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Forum: Tovaxin Posted: Sat Sep 20, 2008 4:03 am Subject: Opexa Announces Top-Line Results from Phase IIb Trial |
I wonder how much of the placebo arm dropped out of the study due to lack of results. That'd obviously skew the stats.
Very disappointing. |
Topic: ACTRIMS + ECTRIMS + LACTRIMS |
rainer
Replies: 11
Views: 761
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Forum: General Discussion Posted: Thu Sep 18, 2008 5:13 pm Subject: ACTRIMS + ECTRIMS + LACTRIMS |
| good stuff! it's hard for me to parse what they mean by "secondary" in the inflammation abstract "Evidence for secondary neurodegeneration in multiple sclerosis". Seems like it says damage is taking ... |
Topic: 6 months anniversary |
rainer
Replies: 19
Views: 858
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Forum: Revimmune (cyclophosphamide or cytoxan) Posted: Wed Sep 17, 2008 7:39 pm Subject: 6 months anniversary |
| I read big mouth Bob's reaction as actually tempering enthusiasm with realistic expectation. |
Topic: Embryonic Stem Cells Reduce M.S. symptoms <:3 |
rainer
Replies: 0
Views: 189
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Forum: Stem Cells Posted: Wed Sep 10, 2008 4:32 pm Subject: Embryonic Stem Cells Reduce M.S. symptoms <:3 |
http://www.medicalnewstoday.com/articles/120874.php
http://www.plosone.org/article/info:doi/10.1371/journal.pone.0003145
Hadassah University Hospital and Hadasit, the technology transfer company ... |
Topic: Back on track |
rainer
Replies: 14
Views: 765
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Forum: Revimmune (cyclophosphamide or cytoxan) Posted: Mon Sep 08, 2008 10:07 pm Subject: Back on track |
| I would try to find an unbiased neuro or maybe even an oncologist and discuss it with them. Gather as much objective info about it as possible. Find out if there have been patients similar to you ... |
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