Full text of recent study at Stony Brook .

sandonpoint · Family Member Joined: Feb 23, 2008 Posts: 26

This is a very interesting technique.

I did a bit of research for those interested the link to read the full text and the is below.

Here is the link

http://rapidshare.com/files/94168957/1388.pdf.html

Cheers

Sandon

chrishasms · Family Elder Joined: Sep 15, 2006 Posts: 1117

what?

Lyon · Family Elder Joined: May 04, 2006 Posts: 5345

Hi Sandon,
At least for us, the link leads to a web hosting site.
Bob

chrishasms · Family Elder Joined: Sep 15, 2006 Posts: 1117

Bob you word things so much better than I do. Very Happy

Lyon · Family Elder Joined: May 04, 2006 Posts: 5345

chrishasms · Family Elder Joined: Sep 15, 2006 Posts: 1117

While I'm in MD@JH I will see what kind of info I can get my hands on, and make sure the wife keeps you up on everything!

Also, I'm sick! With a cold, Bob! LOL

Glad it's now, but I hope the wife gets it quick so she can get it over with. Her boss has it, I have it, so hopefully she is next.

SOOOOOON lol

Loobie · Posted: Sat Feb 23, 2008 10:50 am Post subject:

Bob and Chris,

Rapidshare is a file sharing site. If you go down to the bottom, click the "free download" button and type in the 4 letter code, you get a PDF document from Stonybrook that I found very informative. I'd try it again, but do what I said about clicking the free download. It is not a program you are downloading, but rather the PDF file that someone put out there to be shared. I think it's a lot like the photo sharing sites. Give it one more try, I guarantee you will like the document if you want some "light" reading.

Lyon · Family Elder Joined: May 04, 2006 Posts: 5345

Hi Chris,
No one can tell you not to worry, but I think you are in good hands. It may be a hell of an inconvenience, but if ANYTHING is a concern to JH when it's time for your treatment, they won't risk problems and you'll have to reschedule. I'm sure that would drive you nuts, but it's better than accepting unneccary risk.

You, or someone had mentioned that over 250 people have been treated so far. I'm sure at this point they're getting a pretty good system down.

Thanks Lew,
Now that I've done it, I'm glad you explained. I would never have realized there was a file there to be downloaded.

It's from 2006, the latest HDC paper from Stony Brook I'm aware of. I'd already read it.

I've always found this one interesting. I wrote the researcher about 6 months ago to ask if the lady still was showing no signs of progression, but never got a response http://www.msu.edu/~lyonro/hdcold.pdf

Of course cyclophosphamide has been around for many years, but to my awareness this accidental overdose is the first time that high dose cyclophosophamide ALONE was found to stop the MS disease process.

Bob

chrishasms · Family Elder Joined: Sep 15, 2006 Posts: 1117

Yes I agree with you Bob. I'm in great hands!

I'm done being worried. I'm the only one on either side I can tell thats worried lol!

If someone told me I had cancer I would do chemo so why not this right?

I just wish they would have done some more men in the prelim, but hey here I am!

Lyon · Family Elder Joined: May 04, 2006 Posts: 5345

chrishasms · Family Elder Joined: Sep 15, 2006 Posts: 1117

If you go to the site, and look at the pdf, it shows the breakdown of the original 13.

One of the 13 quit. I have a hell of a time reading all this stuff. It gets jumbled now so if I miss it sorry. Hopefully that goes away as well.

12 of the 13 chosen were woman. The 13 was a woman. 6 of the 13 were RRMS. The rest were SPMS.

The data directly shows a correlation between age, and disease duration. The people with RRMS (activity on MRI) showed the best EDSS improvements while only one of the SPMS showed any. Also it made me happy to see that a good deal of the people were only reporting at 6 or 12 months, not even the full 24 months.

Right now I hear a bell going off too. Sucks I agree but explains the protocol for sure.

So from what I can tell, I got nothing to loose but my life. Razz

I'm being over dramatic lol

Lyon · Family Elder Joined: May 04, 2006 Posts: 5345

Jamie · Family Elder Joined: Jan 08, 2008 Posts: 596

I for one had not read this.

It's a great summing up.

Two weeks to go!

sandonpoint · Family Member Joined: Feb 23, 2008 Posts: 26

Just read the other pdf about the patient in brazil, interesting.

Just a question about this statement towards the end of the article

"We predict that this form of therapy may induce long-term remission in approximately 40% of MS patients, at signiﬁcant enhancement of quality of life compared with any other form of presently available treatment"

Where did they pluck 40% from ?

Cheers

Sandon

chrishasms · Family Elder Joined: Sep 15, 2006 Posts: 1117

If you look at the PDF I think it's because it's improving EDSS in 40% of the patients in the trial. Mostly, the people with RRMS.

I think there idea of remission is showing a clinical improvement just as in Cancer remission, well, you feel better ad show clinical improvement as well. If you are damaged beyond repair that may not be remission.

I think and I say this with a big huge capitalized, I THINK if you have RRMS, and no permanent damage, this is going to be a huge, huge, huge, treatment.

Wow Jamie, 18 days to treatment lol