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Summary: The cause of MS is unknown but some infective agents are thought to play a contributory role. This review article discusses two of the possible candidates, Epstein Barr virus and Chlamydia pneumonia, and the evidence for each of them.
authors: Giovannoni G, Cutter GR, Lunemann J, Martin R, Munz C, Sriram S, Steiner I, Hammerschlag MR, Gaydos CA.
source: Lancet Neurol. 2006 Oct;5(10):887-94.
I have read the whole article and the piece by Giovannoni especially is very good.
Sarah _________________ An Itinerary in Light and Shadow
Completed Stratton/Wheldon antibiotic regime for aggressive secondary progressive MS in June 2007, after four years. Still slowly improving with no exacerbation since starting. EDSS was 7, now 2 or often less.
What I find interesting in this report, is that "Koch took more than a decade to convince his contemporaries that Mycobacterium tuberculosis was the cause of tuberculosis". Can't see the wood for the trees.
PS I subscribe to the Lancet so if anyone wants more information please PM me. There is fascinating stuff on EBV from Gavin Giovannoni and on Chlamydia pneumonia by Sriram at Vanderbilt. If only there were effective anti-viral drugs out there I'd be taking them too.
Joined: Jun 18, 2004 Posts: 1483 Location: Bedfordshire UK
Posted: Thu Nov 16, 2006 5:38 pm Post subject:
Quite, and it took twenty years for the h pylori and stomach ulcer link to be fully recognised. Even more trees.
Now why didn't you mention Hammerschlag's piece, Alex? _________________ An Itinerary in Light and Shadow
Completed Stratton/Wheldon antibiotic regime for aggressive secondary progressive MS in June 2007, after four years. Still slowly improving with no exacerbation since starting. EDSS was 7, now 2 or often less.
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