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Joined: Nov 06, 2004 Posts: 356 Location: Ottawa, Ont. Canada
Posted: Tue Jun 10, 2008 4:04 pm Post subject:
the last sentence of the article suggests that it may decrease the pool of certain important cells so I am not sure it is a perfect drug but I am taking it anyway.. 80 mg every day of Lipitor... too bad
Posted: Wed Jun 11, 2008 4:31 am Post subject: Re: More statin research
carolew wrote:
the last sentence of the article suggests that it may decrease the pool of certain important cells so I am not sure it is a perfect drug but I am taking it anyway.. 80 mg every day of Lipitor... too bad
The abstract appears to be saying that the two statins tested induced parenchymal glial progenitor cells to differentiate into oligodendrocytes as opposed to other types of glial cells. This might be a good effect for MS patients as it would be hard to argue against having more oligodendrocytes available for remyelination (if that is indeed the correct interpretation).
"This one is so important as statins have been used in treating MS for "unexplained" reasons, usually attributed to their anti-inflammatory effect. Similarly, how much of the lowered risk in cardiac disease is due to the anti-bacterial effect of statins vs their cholesterol effect? Of course, denying cholesterol to Cpn inclusions also fights the Cpn (according to the science on delta-tocotreinols)." Jim Kepner
_________________ An Itinerary in Light and Shadow
Completed Stratton/Wheldon antibiotic regime for aggressive secondary progressive MS in June 2007, after four years. Still slowly improving with no exacerbation since starting. EDSS was 7, now 2 or often less.
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