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Posted: Wed Feb 27, 2008 4:16 pm Post subject: Leeches not worms
Lyon,
I've always regarded you as a parasite - sucking the life out of a once great MS website. Even Arron has thrown himself off the Golden Gate Bridge out of desperation. NHE has upped his dose of anti-depressants as his attempts to rein in your posts have failed. But you and your like may be of some use after all. Leeches may be a future weapon against MS.
I just read a story today on medicalnewstoday.com about proteins being the possible cause of Parkinson's disease. We already know that a protein is being blamed for Alzheimer's disease.
Maybe a treatable protein really is the cause of MS. How great would that be??
Joined: May 04, 2006 Posts: 3403 Location: Mid-Michigan
Posted: Wed Feb 27, 2008 9:59 pm Post subject: Re: Leeches not worms
bromley wrote:
Lyon,
I've always regarded you as a parasite - sucking the life out of a once great MS website.
Thank you Ian!....I'm something of a self professed expert on British culture and mannerisms and therefore I'm aware that it's very difficult for the British to give or receive compliments. That was an admirable first attempt to defy your British heritage and give me a compliment. With a little more practice you'll be singing me praises with the best of them!
Seriously, I haven't finished the entire article yet but I was (and am) absolutely unfamiliar with this particular situation. It's interesting that it seems the researchers are tying the effect in with the anti-clotting factor. When the leech accesses the blood it is also initiating an interaction with the immune system and it seems more logical that the noticed effect on the immune system is tied in with that.
Bob _________________ Wife diagnosed with MS in Feb. 2006 and is a participant in the Tovaxin IIb clinical trial.
Joined: Mar 26, 2005 Posts: 595 Location: Northamptonshire, England.
Posted: Sun Mar 02, 2008 10:05 am Post subject:
This definitely steers us back towards the, " MS as a vascular disease", theory. Fibrinogen, (a protein involved in blood clotting), has been identified previously as being involved in the MS process and I seem to recall we had some threads on the subject. Also the notion that these clotting proteins shoehorn open the tight junctions between endothelial cells and allow blood products into the brain sounds like a prime candidate for the cause of a leaky blood brain barrier.
Sounds as if good progress has been made toward stopping the harmful effects of these proteins without interfering with the clotting process itself:
Bob, if you gained your Ph.D. on British culture from American television you will be well aware that we all live in country mansions, have a butler, talk like the Queen or the Beatles, and have bowler hats surgically implanted at puberty.
I regret to inform you that this is only true of Ian. _________________ Dom
Joined: May 04, 2006 Posts: 3403 Location: Mid-Michigan
Posted: Sun Mar 02, 2008 11:31 am Post subject:
TwistedHelix wrote:
Bob, if you gained your Ph.D. on British culture from American television you will be well aware that we all live in country mansions, have a butler, talk like the Queen or the Beatles, and have bowler hats surgically implanted at puberty.
I regret to inform you that this is only true of Ian.
There you go again with that British modesty Dom!
Bob _________________ Wife diagnosed with MS in Feb. 2006 and is a participant in the Tovaxin IIb clinical trial.
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