DrSclafani answers some questions

A forum to discuss Chronic Cerebrospinal Venous Insufficiency and its relationship to Multiple Sclerosis.
User avatar
drsclafani
Family Elder
Posts: 3181
Joined: Fri Mar 12, 2010 3:00 pm
Location: Brooklyn, New York
Contact:

Re: DrSclafani answers some questions

Post by drsclafani » Mon Dec 12, 2011 4:41 pm

munchkin wrote:Dr. S

Thank you for your work with IVUS, what an amazing reduction in vein injury.

Based on the reduction of trauma to the vein using IVUS have you been able to recommend parameters on sizing of balloons based on the corresponding vein size?
Will this information help establish a set of guidelines for treatment protocols?
munchkin, that is the goal of the paper. balloon selection will be based upon the circumference of the vein above and below the point of stenosis.
Salvatore JA Sclafani MD
Patient contact: ccsviliberation@gmail.com

User avatar
drsclafani
Family Elder
Posts: 3181
Joined: Fri Mar 12, 2010 3:00 pm
Location: Brooklyn, New York
Contact:

Re: DrSclafani answers some questions

Post by drsclafani » Mon Dec 12, 2011 6:23 pm

mo_en wrote:May i add (ask) that muscles of the neck and upper back with reduced flexibility due to venous outflow obstructions put more strain on neck veins and thus worsen the outflow problem itself (?).
its possible.

we need other clinical specialties to do this work with us!
Salvatore JA Sclafani MD
Patient contact: ccsviliberation@gmail.com

User avatar
drsclafani
Family Elder
Posts: 3181
Joined: Fri Mar 12, 2010 3:00 pm
Location: Brooklyn, New York
Contact:

Re: DrSclafani answers some questions

Post by drsclafani » Mon Dec 12, 2011 6:26 pm

Cece wrote:What a great weekend this would be for a case report! :-D
Or is there nothing new under the sun to show us?
(I understand too if time is short and duties long.)

Cece
great case today. Will share tomorrow

S
Salvatore JA Sclafani MD
Patient contact: ccsviliberation@gmail.com

User avatar
NZer1
Family Elder
Posts: 1624
Joined: Thu Feb 18, 2010 3:00 pm
Location: Rotorua New Zealand

Re: DrSclafani answers some questions

Post by NZer1 » Mon Dec 12, 2011 9:18 pm

drsclafani wrote:
mo_en wrote:May i add (ask) that muscles of the neck and upper back with reduced flexibility due to venous outflow obstructions put more strain on neck veins and thus worsen the outflow problem itself (?).
its possible.

we need other clinical specialties to do this work with us!
Dr. S,
I gather that you have some insight on the muscle issues in the neck and upper back. IMO this a common complaint in MS and other diseases.

Can you give more info, food for thought as this in itself must be part of a cycle effect where it effects posture and then compounds flow issues and nerve conduction issues. Some thing I have personally experienced and hear of in my MS community.

Thanks, Nigel

Cece
Family Elder
Posts: 9331
Joined: Mon Jan 04, 2010 3:00 pm
Contact:

Re: DrSclafani answers some questions

Post by Cece » Tue Dec 13, 2011 7:33 am

drsclafani wrote:Cece
great case today. Will share tomorrow

S
That is happy news. :)

User avatar
drsclafani
Family Elder
Posts: 3181
Joined: Fri Mar 12, 2010 3:00 pm
Location: Brooklyn, New York
Contact:

Re: DrSclafani answers some questions

Post by drsclafani » Tue Dec 13, 2011 7:44 am

pelopidas wrote:I had a terrible chronic neck pain and occipital headache (in the back of my head) for the past 7-8 years.
MRI showed some mildly prolapsed cervical disk, so i thought i would live with it forever. I was having physiotherapy and i was taking pain killers almost every second day.
Then, 6 months ago (6/10/2011) i had my angioplasty procedure.
One month later i was talking to Dr Sclafani about the great improvements i already had. I mentioned that my neck pain was unexpectedly disappeared. He replied only "Ah, it was the spasm!"

I found what he meant:

Image
this is the anatomy and the vessels of the sternocleidomastoid muscle (only the arteries here, the veins were of no importance until recently)

Image
almost 90% of this pair of muscles has venous outflow through the jugulars
Maybe the spasm was some symptom of venous congestion of the muscles.
I am relieved of the neck pain and i can turn and flex my head so easily now.
I hope that this will last forever and so will all my other improvements.
Maybe other people have experienced the same thing.
Muscles have veins, too!

Thank you again Dr Sclafani (and this one is a special 6 months post-op thank you)!
-and thank you Cece for the image uploading advice!
glad you are a poster child for ccsvi. you are a lucky one. not everyone has such great responses. but it could not happen to a nicer woman.

a hint on sharing images on TIMS: dont use URL, use Image. This command will push the image directly into your email. your audience will not have to press on the link. see your image by my technique. They show directly in the post.

very interesting hypothesis regarding reduction of neck pain.what about this consideration: patients with MS often havfe very large condylar emissary veins that connect to the veins in the posterior neck. Could relieving the resistance in the IJV, reduce flow through the emissary vein and thus reduce venous congestion in the neck muscles?


Sal
Salvatore JA Sclafani MD
Patient contact: ccsviliberation@gmail.com

User avatar
drsclafani
Family Elder
Posts: 3181
Joined: Fri Mar 12, 2010 3:00 pm
Location: Brooklyn, New York
Contact:

Re: DrSclafani answers some questions

Post by drsclafani » Tue Dec 13, 2011 8:47 am

Cece wrote:
drsclafani wrote:Cece
great case today. Will share tomorrow

S
That is happy news. :)
Here you go, Cece. A very interesting case indeed. Not completely resolved yet, but very illustrative of some of the complexity of CCSVI management.

The patient is a 59 year old Canadian Caucasian female diagnosed initially with relapsing remitting multiple sclerosis in 1971. She was treated by steroids for very infrequent relapses over the first 25-30 years but there was gradual deterioration of function and she appears to have regressed to the secondary progressive form of the disease 6-8 years ago. Her initial symptoms were numbness and fatigue, but she has gradually developed and currently exhibits severe weakness in both lower extremities, spotty numbness in both legs and both arms with varying degrees of loss of light touch and sharp/dull discrimination, with intact positional sense and stereognosis. She uses a scooter primarily because of severe imbalance (Rhomberg's test is grossy abnormal) and to a less degree because of weakness. She has MS hugs predominantly in the extremities, has heat intolerance, and spasms in her legs. She has urinary urgency and frequent nocturia.
In October 2010 she underwent (with another IR) venography and angioplasty. Bilateral internal jugular venoplasty was performed with excellent flow on the right and poor outflow on the left after venoplasty. While unclear, it appears that left jugular stenting was performed because of this poor outflow. Azygography was interpreted as normal.
She had fairly early and increasing improvements in fatigue, numbness and tingling and motor weakness and she greatly improved her activities and her exercising. However imbalance persisted.
In the past two months she has regressed and many of her symptoms are returning and she sought consultation with me.
My examination was pertinent for grossly positive Rhomberg sign, severe weakness in both lower extremities (left worse than right), patchy numbness and insensitivity to light and sharp touch, , inability to walk, and a mottled erythema in both lower extremities.
Venography was performed via a left saphenous approach. I will show representative images and then follow with more detail:

RIGHT INTERNAL JUGULAR VENOGRAM:
Image

LEFT INTERNAL JUGULAR VENOGRAM:
Image

AZYGOUS VENOGRAPHY:
Image

LEFT RENAL VENOGRAPHY:
Image

Any questions?
Salvatore JA Sclafani MD
Patient contact: ccsviliberation@gmail.com

Cece
Family Elder
Posts: 9331
Joined: Mon Jan 04, 2010 3:00 pm
Contact:

Re: DrSclafani answers some questions

Post by Cece » Tue Dec 13, 2011 10:38 am

drsclafani wrote: LEFT INTERNAL JUGULAR VENOGRAM:
Image
That just hurts to see. But you were able to get the catheter through it.

I have not seen many renal venograms yet, so cannot say for sure, but is that nutcracker syndrome?

User avatar
elliberato
Family Member
Posts: 82
Joined: Wed Aug 04, 2010 2:00 pm
Contact:

Re: DrSclafani answers some questions

Post by elliberato » Tue Dec 13, 2011 10:47 am

can she walk or has she seen any improvements since your procedure?

User avatar
bestadmom
Family Elder
Posts: 722
Joined: Mon May 18, 2009 2:00 pm
Location: CT
Contact:

Re: DrSclafani answers some questions

Post by bestadmom » Tue Dec 13, 2011 10:51 am

Can you post the azygous IVUS images, pls?

User avatar
drsclafani
Family Elder
Posts: 3181
Joined: Fri Mar 12, 2010 3:00 pm
Location: Brooklyn, New York
Contact:

Re: DrSclafani answers some questions

Post by drsclafani » Tue Dec 13, 2011 11:13 am

elliberato wrote:can she walk or has she seen any improvements since your procedure?
eliberato:
The procedure was concluded and she was discharged yesterday around 1:30 pm. Your expectations are too high.

Let's ask and answer some questions and let this case unfold. The story is just begun.
Salvatore JA Sclafani MD
Patient contact: ccsviliberation@gmail.com

User avatar
drsclafani
Family Elder
Posts: 3181
Joined: Fri Mar 12, 2010 3:00 pm
Location: Brooklyn, New York
Contact:

Re: DrSclafani answers some questions

Post by drsclafani » Tue Dec 13, 2011 11:19 am

Cece wrote:
drsclafani wrote: LEFT INTERNAL JUGULAR VENOGRAM:
Image
That just hurts to see. But you were able to get the catheter through it.

I have not seen many renal venograms yet, so cannot say for sure, but is that nutcracker syndrome?
what do you think that i got through? What do you see in the jugular view?

the nutcracker syndrome requires venographic or CT evidence of obstruction, typically where the renal vein enters the inferior vena cava, collateral flow, symptoms. What do you see? Does the history have any symptoms of nutcracker?
Salvatore JA Sclafani MD
Patient contact: ccsviliberation@gmail.com

User avatar
drsclafani
Family Elder
Posts: 3181
Joined: Fri Mar 12, 2010 3:00 pm
Location: Brooklyn, New York
Contact:

Re: DrSclafani answers some questions

Post by drsclafani » Tue Dec 13, 2011 11:20 am

bestadmom wrote:Can you post the azygous IVUS images, pls?
What do you see on the venogram? I will show the IVUS of everything in good time.
Salvatore JA Sclafani MD
Patient contact: ccsviliberation@gmail.com

User avatar
bestadmom
Family Elder
Posts: 722
Joined: Mon May 18, 2009 2:00 pm
Location: CT
Contact:

Re: DrSclafani answers some questions

Post by bestadmom » Tue Dec 13, 2011 11:30 am

It looks like theres an obstruction at the arc of the azygous, just to the right of where it bulges.

User avatar
mo_en
Family Member
Posts: 48
Joined: Thu Dec 09, 2010 3:00 pm
Location: Patras, Greece

Re: DrSclafani answers some questions

Post by mo_en » Tue Dec 13, 2011 1:19 pm

The right internal jugular has a messy valvular area and a curious stenosis above it. Is it the external jugular receiving some dye?

The left internal must have severe intimal hyperplasia because of the stent around its upper side, leaving only a small channel for the catheter. The dye goes all around the other side to the right internal jugular which means that the confluence of sinuses is clear inside the head.

In the azygous view, is there a dye congestion/reverse flow in the lower branches or just an early picture?

Post Reply
  • Similar Topics
    Replies
    Views
    Last post