Are there any vaso-constricting characteristics of this drug? and how long did it take to get this trial up and running?For example, we know that levels of a protein called TNF-alpha are elevated in active MS and that drugs that block TNF-alpha are helpful in rheumatoid arthritis. However, drugs to block TNF-alpha actually made MS worse in clinical trials.
further down..Are CCSVI and MS related?
Many people hope that CCSVI will prove to be the cause of MS but, at present, this idea is
not supported by fact. Furthermore, it does not seem likely that MS causes CCSVI.
?? contradictory and confusing??If proven, the association between MS and CCSVI may actually be explained by MS causing CCSVI. The Inflammatory proteins related to MS travel through the major veins draining the brain, and may cause the veins to simply show changes consistent with inflammatory cell contact. In the Buffalo study, a higher frequency of CCSVI was seen in MS patients with more severe disease; this is most consistent with MS causing CCSVI.