If autoimmunity were the only problem --

A forum to discuss Chronic Cerebrospinal Venous Insufficiency and its relationship to Multiple Sclerosis.
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1eye
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If autoimmunity were the only problem --

Post by 1eye » Mon Nov 19, 2012 9:30 am

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Re: If autoimmunity were the only problem --

Post by Cece » Mon Nov 19, 2012 9:36 am

if we were mice....

But it's encouraging, and did you see where it said that something similar but using people's own white blood cells was in phase I/II trials?

let me find it
The study's method is the same approach now being tested in multiple sclerosis patients in a phase I/II clinical trial -- with one key difference. The trial uses a patient's own white blood cells -- a costly and labor intensive procedure -- to deliver the antigen. The purpose of the new study was to see if nanoparticles could be as effective as the white blood cells as delivery vehicles. They were.

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Re: If autoimmunity were the only problem --

Post by 1eye » Mon Nov 19, 2012 10:38 am

Sounds like the Opexa trial, and it sounds like they don't need the Tcells. Remember that the Opexa method uses white cells that have been determined to 'remember' myelin.
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Re: If autoimmunity were the only problem --

Post by Cece » Mon Nov 19, 2012 11:48 am

The conditions of CCSVI could set off autoimmunity that continues even after CCSVI is treated. So treatments for autoimmunity would still be needed. It's good to see the research progress, however slowly. I'll look up Opexa, thanks.

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