T Reg cells

If it's on your mind and it has to do with multiple sclerosis in any way, post it here.
Post Reply
User avatar
bromley
Family Elder
Posts: 1888
Joined: Fri Sep 10, 2004 2:00 pm

T Reg cells

Post by bromley » Mon Oct 09, 2006 1:08 pm

I know it's EAE, but I think we'll be hearing a lot more about T Reg cells in the future.

http://www.msif.org/en/research/researc ... expan.html

User avatar
Shayk
Family Elder
Posts: 785
Joined: Fri Feb 06, 2004 3:00 pm
Contact:

T Reg Cells and Estrogen

Post by Shayk » Mon Oct 09, 2006 6:20 pm

Hi Ian

I think estrogen might be something they're looking at re: T Reg Cells.

Here's a dry abstract on the topic.
Estrogen (E2)-induced immunomodulation involves dual effects on antigen-presenting cells (APC) and CD4(+)CD25(+) regulatory T cells (Treg) but not a direct effect on effector T cells.
That study builds on earlier research--Cutting edge: estrogen drives expansion of the CD4+CD25+ regulatory T cell compartment.

I hope we hear more about estrogen. :wink: I'm fearful it's going to go undercover rapidly since they they're still trying to find funding for the Phase II estriol trial (with Copaxone no less). :(

Sharon

Post Reply
  • Similar Topics
    Replies
    Views
    Last post