Sinusitus and MS
Sinusitus and MS
For the first time, I saw a post on a different thread from Lyndacarol considering a link between MS and Sinusitis. I was very interested as I have, like all of you, tried to find my own personal connection. Due to a facial accident years ago, I have gone through numerous surgeries and procedures to repair a completely screwed up sinus system. When I get MRI's my tech always tells me that the MS is one thing but the sinus issue is going to kill me. It has been impossible for me not to connect the two. I found this old study and have to wonder why there has not been more attention given to this. Any one else out there with more info?
Thank,
Lars
Multiple sclerosis and sinusitis
Sir,
A research project in general practice showed an association between multiple sclerosis and sinusitis.1 More and more evidence is accumulating to support a hypothesis that in multiple sclerosis the central nervous system is subjected to 'showers' of endotoxins from anaerobic commensal bacteria which grow in diseased mucosal tissue of the sphenoid and ethmoid sinuses. These endotoxins pass into the cerebrospinal fluid through bony defects which are frequently present in the sphenoid. From the cerebrospinal fluid these 'noxious substances' reach the tissues of the brain and cord via the Virchow-Robin spaces and demyelinating lesions arise.
A great barrier to discovering the cause of multiple sclerosis has been the lack of post-mortem material. When a patient with multiple sclerosis dies the general practitioner or consultant rarely asks for a post-mortem because they know the cause of death. We wonder if general practitioners could help our research by obtaining permission for us to examine the brain and cranial cavity of any of their patients who die with a diagnosis of multiple sclerosis. A complete autopsy would not be requested. We would be prepared to attend anywhere at any time.
GEORGE DICK
Waterland
Rowhook
Horsham
West Sussex RH12 3PX
DEREK GAY
Green Storthe
Coast Road
West Mersea, Colchester
Essex C05 8LS
Reference
1. Gay D, Dick G, Upton G. Multiple sclerosis associated with sinusitis: a case controlled study in general practice. Lancet 1986; 1: 815-819.
172 Journal of the Royal College of General Practitioners, April 1988
- cheerleader
- Family Elder
- Posts: 5360
- Joined: Mon Sep 10, 2007 2:00 pm
- Location: southern California
I was also interested in LyndaCarol's reference. Thanks for taking the ball and running with it. My husband has a severe deviated septum, nasal allergies, and a jolly red nose. He just went on a sneezing jag, sitting next to me, for several minutes. He's rarely sick, but his nose is never "well."
Here's a thread regarding nasal drug administration and the access of the blood brain barrier thru the sinus cavity. Might be of interest to you.
http://www.thisisms.com/ftopict-5080-nasal.html
There's certainly some sort of correlation. Let's put our noses together.
best,
AC
dx dual jugular vein stenosis (CCSVI) 4/09
http://ccsviinms.blogspot.com
- cheerleader
- Family Elder
- Posts: 5360
- Joined: Mon Sep 10, 2007 2:00 pm
- Location: southern California
Here's a product I was interested in checking out, might help stop paranasal sinus infections...."SinoFresh"
http://www.natlallergy.com/product.asp? ... 1203274545
AC
dx dual jugular vein stenosis (CCSVI) 4/09
http://ccsviinms.blogspot.com
Interesting stuff.
The sinus rinse kits are inexpensive, and are easy to use - I would recommend giving them a try.
Sharon
is the problem perhaps that we feel we have to categorize, and assign a label to health issues, regardless of whether there's a known specific cause?
- cheerleader
- Family Elder
- Posts: 5360
- Joined: Mon Sep 10, 2007 2:00 pm
- Location: southern California
Thanks for the neti pot reminder. Saw it on Oprah's show with Dr. Oz, made a mental note and promptly forgot!
Thanks for the Neilmed suggestion, too, Sharon.
Lars, I wonder what the MRI tech was referring to, as to your deadly sinuses? Can you tie your injury to your MS diagnosis?
And JL....it's just another thing to add to our long list of questions. I agree with you, MS is probably a label, an "umbrella" diagnosis for a process that begins with the breach of the blood brain barrier by some foreign agent, causes a hyper alert immune system's cells to attach to look-alike myelin and begin the process of axonal death in the CNS.
AC
dx dual jugular vein stenosis (CCSVI) 4/09
http://ccsviinms.blogspot.com
For me the titles and labels are unimportant, as long as I am one of the afflicted group I can never stop wondering what caused this. I think as ms'ers it is sort of our calling to be as "detective" as possible. No one knows as much about a (possibly mythical) common thread as we do. That said I must admit that this sinus connection is as much a personal hunch as anything else. Although, I was happy to see the article I posted as reinforcement. It's just that sooo many of those I meet have the same issue. My time line is as follows; Rodeo accident in 1977 full facial reconstruction (poorly done). Constant sinus infection for years. 1993; correct massively deviated septum, repair bone structure and clean sinus passage. Late 90's remove polyps, open sinuses. 2006; haven't taken a breath through my nose in years, can't smell a thing, breathing through my mouth is becoming an issue. Talk of throat cancer. Talk of Asthma. A scope shows incredible polyp growth in every conceivable area. MRI cites massive sinusitis first and nearly a dozen lesions due to MS, SECOND. Hard not to feel some connection. I would love to see further study.
Sorry for the long babble!
Take Care,
Lars
- lyndacarol
- Family Elder
- Posts: 3392
- Joined: Thu Dec 22, 2005 3:00 pm
- Contact:
American Academy of Otolaryngology
Specifically, http://www.entnet.org/healthinfo/sinus/ ... enoid2.cfm is very interesting with these sentences: "The sphenoid sinus is adjacent to the main nerve that is responsible for vision, the optic nerve. The main artery that goes to the brain, the carotid artery, travels along the wall of this sinus."
Does it seem like all roads are leading to the sphenoid? Optic neuritis, lesions in the brain??? And so many folks I know with MS report sinus infections, sinusitis, allergies, even one with CONSTANT throat-clearing tho she says she has no sinus problems!
A later thought: Could the statins and other anti-inflammatories actually be working on inflammation in the sinuses??
- TwistedHelix
- Family Elder
- Posts: 599
- Joined: Fri Mar 25, 2005 3:00 pm
- Location: Northamptonshire, England.
I've never had sinus problems as such, but my nose drips constantly , and so did my mother's, (hence the standing joke: " noses run in our family"), and I always had a sneaking suspicion that MS and our high tissue bills were linked,