I have never really experienced spasticity. I have had considerable stiffness during my last attack. I am not worried about symptoms increasing initially, I will deal with that as it comes.
My question is, will starting straight away at 4.5 mg make the treatment less effective for some reason or is it just jumping on to a rougher ride rather than accelerating up? Anyone out there have good/bad experiences taking this dose. I am male, 22 years old RRMS, main symptoms currently numbness and tingling in hands some "Hug" that comes and goes.
I have heard someone say it is better to start off at 4.5 mg rather than work your way up, and others say start at 2 mg. Some don't do so well at 4.5 mg but say they do great at 3 mg. Problem with LDN is that a lot of people have opinions, but few (if anyone) really know what the best dosages are.
I don't know how 4.5 mg was derived. Seems that the dosage should be related to weight, and why not 4 mg or 5 mg? I guess a doctor somewhere decided that 4.5 mg was the ideal dosage, but I don't think there were any scientific studies to show what the ideal dosage for MS patients actually is.
If you have 4.5 mg pills, I guess give it a try and see what happens. Let us know. I started off at 2 mg and am working up slowly, getting to 3 mg. No problems so far that I can tell, but some dreams are a bit more vivid and interesting than normal. No nightmares, just wierd things.
Best of Luck!!!!!!
I have been taking LDN for just under two years.
Why do you think that the few drug trials of LDN have not been a shining success? Did the drug dose meet the needs of the patient or did the patient meet the needs of the drug trials?
What you should have done is order LDN in LIQUID form. One uses a graduated dropper. Start at 1mg and gradually ramp up by 0.5 ml increments over a period of many weeks or even months. You keep increasing, hopfully feeling better and better until you start feeling worse again ... then fall back to the dose where you felt best. When, and only when, you are stable on that established dose do you fork out your hard-earned money on LDN capsules of a fixed dose.
I am totally freaked out by this... what studies? Do you have any links? I just started LDN (have been on it for 5 days) and have stopped taking tecfidera, so no longer on MS drugs. Super worried maybe I'm being foolish?
Also, I took 1.5mg first night. Then the next night I took 3mg and now I'm taking 4.5mg. I have absolutely NO side effects or reaction to taking LDN, which is why the dosage was increased so quickly. Is this unusual to not have any side effects? As it does not affect my sleep at all, nothing!... which is great. I use skip's pharmacy (who are really good) so i know I'm not getting a "bad batch".
There have been a few studies of LDN on MS and all have shown positive results so maybe Supaguy can explain his post a bit more?LillyMS wrote: I just started LDN (have been on it for 5 days) and have stopped taking tecfidera, so no longer on MS drugs. Super worried maybe I'm being foolish?
That being said i personally would NOT rely on LDN as my primary treatment for MS. The studies that have been done don't focus on the items i would be most interested in such as disease progression and lesion load. While they do touch on this the primary purpose was on quality of life scores. I would love to be on Tec but my insurance does not cover it so I stick myself with Copaxone every night. I also incorporate diet, exercise and supplements to my regimen. They say one of the best ways to know if your dose is too high is joint pain. I don't have side effects to many meds, LDN being no exemption to this rule so i wouldn't be too concerned about the lack of side effects.
I strongly suggest you read the links below if you are concerned.
http://www.tccompound.com/editor/user_i ... l-0309.pdf
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Many people quit taking it because they don't feel any benefits and it could be just because their dosage was slightly too high. Skips are very helpful to assist anyone with this drug.
Take Care All
On LDN since Sept. 2012 with better quality of life.
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