what we know about MS as of 2017

A forum to discuss research on the origins of MS and its development.
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what we know about MS as of 2017

Post by frodo » Sun Aug 13, 2017 1:22 pm

This is a copy of another post of Leonard. I copy and paste here to have all the references in this subforum

Source: http://www.thisisms.com/forum/general-d ... 8-825.html
The causes and very mechanisms underlying MS are set out in the Skeleton and synopsis under the links:

http://www.thisisms.com/forum/general-d ... ml#p248066
http://www.thisisms.com/forum/general-d ... ml#p245692
[and there may be some further useful ideas in here: http://www.mshackathon.nl/wp-content/up ... ressed.pdf ]

The ACTRIMS Feb 2017 Florida Forum covers exactly the same ingredients and would seem to confirm the thinking. See:
https://multiplesclerosisnewstoday.com/ ... o-florida/
The focus ... will be environmental factors, genetics, and epigenetics in MS susceptibility and clinical course. Presenters will disclose recent advances on the relationship between MS susceptibility and diet; the effects of sex chromosomes, hormones, and puberty on the risk of MS and the clinical course of the disease; reveal emerging data on the role of the microbiome in MS development; review controversies regarding the role of viruses in MS; convey state-of-the-art data on genetic and epigenetic factors as risk factors and disease modulators in MS; and other MS-related topics of interest. unquote
http://www.actrims.org/forum2017/index. ... -abstracts
http://www.actrims.org/forum2017/index. ... t-a-glance

The therapeutic options mentioned under the first link above flow directly from a basic understanding of the disease.

The work by GeNeuro and ATARA Bio are commercially driven. Companies try to find “access points” in the complex cascade, for medication to halt the disease and, to create new shareholder value:
https://www.geneuro.com/data/documents/ ... y-2017.pdf
http://files.shareholder.com/downloads/ ... e_2017.pdf
Or raise profit as here turning one mab into the other: http://www.wheelchairkamikaze.com/2017/ ... l?spref=fb

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