Biomarkers: Response to Glatiramer Acetate predictable

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frodo
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Biomarkers: Response to Glatiramer Acetate predictable

Post by frodo » Sun Jul 22, 2018 10:26 am

It seems that a biomarker in blood predicts response to GA

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Phosphorylated SIRT1 as a biomarker of relapse and response to treatment with glatiramer acetate in multiple sclerosis

https://www.sciencedirect.com/science/a ... 0018302314

Highlights

• We investigated the role of p-SIRT1 and H3K9me3 as biomarkers in multiple sclerosis.
• P-SIRT1 was found to be a biomarker of disease activity.
• H3K9me3 was also found to be a biomarker of clinical activity.
• H3K9me3 was found to be a biomarker of response to glatiramer acetate treatment.

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