Search found 5063 matches

by NHE
Thu May 23, 2019 6:47 am
Forum: Mavenclad (Cladribine)
Topic: cladribine / leustatin / mavenclad
Replies: 25
Views: 1820

Re: cladribine / leustatin / mavenclad

Hey I just got an email ad for Mavenclad (cladribine) and its apparently approved, but my doctor friend says never take a new treatment in the first 25 years. Give them time to debug. Well, the prescribing information has a black box warning about an increased risk of cancer. Caution seems to be th...
by NHE
Wed May 22, 2019 3:24 am
Forum: Chronic Cerebrospinal Venous Insufficiency (CCSVI)
Topic: Cerebral blood-flow clinical trial
Replies: 2
Views: 107

Re: Cerebral blood-flow clinical trial

Bosentan, interesting! https://en.wikipedia.org/wiki/Bosentan I would try it if it were available. You may wish to read some prior discussion on Bosentan. https://www.thisisms.com/forum/viewtopic.php?p=257125#p257125 I'm currently taking PQQ as well as ginkgo to try to help cerebral blood flow.
by NHE
Mon May 20, 2019 12:03 pm
Forum: General Discussion
Topic: Remyelination
Replies: 5
Views: 278

Re: Remyelination

2019 Apr 18 Bethune Institute of Epigenetic Medicine, The First Hospital, Jilin University, China Small Molecules with Big Promises for Curing Demyelinating Diseases https://www.ncbi.nlm.nih.gov/pubmed/31002801 Here's the abstract of the paper that letter discusses. Diverse Chemical Scaffolds Enhan...
by NHE
Sat May 18, 2019 11:14 am
Forum: General Discussion
Topic: Optic Neuritis & Corrective Lenses
Replies: 1
Views: 37

Re: Optic Neuritis & Corrective Lenses

So, I've had nearsightedness since I was little. It's pretty significant, but since my first attack that started last month, I developed optic neuritis. The steroids didn't completely eradicate it, though I can see much better in that eye now. My question is this: can you still get corrective lense...
by NHE
Tue May 14, 2019 11:51 pm
Forum: Undiagnosed
Topic: Diagnosed with CIS today, more tests to come - things to know/ask?
Replies: 48
Views: 1024

Re: Diagnosed with CIS today, more tests to come - things to know/ask?

In terms of actually exercising, when would you say it's safe to try doing something like bike riding again? Is it too dangerous to attempt with any tremor at all, or might it actually help overall by stimulating a lot of the leg muscles? Do you have access to a stationary exercise bike? If so, it ...
by NHE
Mon May 13, 2019 10:30 am
Forum: Coimbra High-Dose Vitamin D Protocol
Topic: Dr. Coimbra Protocol
Replies: 235
Views: 20693

Re: Dr. Coimbra Protocol

ElliotB wrote:
Mon May 13, 2019 10:17 am
Have you ever tried splitting you daily dose into two, talking half in the morning and the other half in the evening?
Taking D3 at night can interfere with your sleep since it's been found to reduce melatonin production.

viewtopic.php?p=254498#p254498
by NHE
Mon May 13, 2019 12:29 am
Forum: General Discussion
Topic: Immune tolerance
Replies: 1
Views: 87

Re: Immune tolerance

Petr75 wrote:
Sun May 12, 2019 8:06 am
Immune tolerance in multiple sclerosis and neuromyelitis optica with peptide-loaded tolerogenic dendritic cells in a phase 1b trial.
Free full text.

https://www.pnas.org/content/pnas/116/17/8463.full.pdf
by NHE
Sat May 11, 2019 8:35 pm
Forum: General Discussion
Topic: Aubagio
Replies: 2
Views: 72

Re: Aubagio

Hello all. I would first like to say how grateful I am that this site and all of you people exist and are here for me. I just recently stopped taking a Aubagio. I recently adopted the diet and exercise plan from Matt Embry at mshope.com. I am very curious to know If anyone knows about this medicati...
by NHE
Sat May 11, 2019 7:32 pm
Forum: Undiagnosed
Topic: Diagnosed with CIS today, more tests to come - things to know/ask?
Replies: 48
Views: 1024

Re: Diagnosed with CIS today, more tests to come - things to know/ask?

The Tecfidera is also has a similar problem. It was derived from observations that a topical psoriasis cream made of dimethyl fumarate seemed to lessen MS symptoms . That led to an oral drug called BG12, then a drug called Fumaderm, then onto Tecfidera. They just don't know how it works. The thinki...
by NHE
Sat May 11, 2019 7:08 pm
Forum: Undiagnosed
Topic: Diagnosed with CIS today, more tests to come - things to know/ask?
Replies: 48
Views: 1024

Re: Diagnosed with CIS today, more tests to come - things to know/ask?

I've tried melatonin in the past, and it tends to cause stomach upset for me, but I'll try it again with no other options. I'd rather not go back on sleeping pills, as I never felt that they gave me very restful sleep, and I was one of the people with the rare adverse effect of hallucinations while...
by NHE
Thu May 09, 2019 11:12 pm
Forum: Chronic Cerebrospinal Venous Insufficiency (CCSVI)
Topic: Dayton Interventional Radiology
Replies: 6
Views: 145

Re: Dayton Interventional Radiology

I think one thing that Dr. Sclafani's discussion has demonstrated is that use of intravascular ultrasound (IVUS) is critical for successful treatment. It helps to determine an accurate size of the vein thereby avoiding over stretching and damaging the vein and also helps avoid under treatment minimi...
by NHE
Thu May 09, 2019 2:27 am
Forum: Undiagnosed
Topic: Diagnosed with CIS today, more tests to come - things to know/ask?
Replies: 48
Views: 1024

Re: Diagnosed with CIS today, more tests to come - things to know/ask?

Update: Had my brain MRI this afternoon, and the neurologist called tonight to let me know that there were a lot of lesions on it. Some were brand new and lit up, but he didn't know how old the non-lit ones were, just that they're newer than 4 years, since my brain MRI in 2015 was clean. He can't d...
by NHE
Wed May 08, 2019 8:11 pm
Forum: Introductions
Topic: Hello! New member with a question
Replies: 12
Views: 326

Re: Hello! New member with a question

BigDaddy wrote:
Wed May 08, 2019 3:50 am
Is CBD oil any good?
CDB oil is fine. The quality of the product will vary with the manufacturer. The CDB industry is still in its infancy. One reputable source though is CW Hemp. https://www.charlottesweb.com/ There are likely others as well.
by NHE
Wed May 08, 2019 12:01 am
Forum: Introductions
Topic: Hello! New member with a question
Replies: 12
Views: 326

Re: Hello! New member with a question

Interestingly enough, last night my wife gave me a massage with lavender oil. Be careful with lavender oil. It's been reported to activate estrogen receptors. I think it's best to just avoid it. Prepubertal gynecomastia and chronic lavender exposure: report of three cases. https://www.ncbi.nlm.nih....
by NHE
Tue May 07, 2019 11:32 pm
Forum: Undiagnosed
Topic: Optic neuritis
Replies: 15
Views: 213

Re: Optic neuritis

Thanks , some interesting reads for sure. Well one thing i know for certain is I prob do lack vitamin d ... Its only sunny and warm here for 3 months out of the year if we are lucky. Haha. I am relieved that my eye is mostly back to normal though.... I hope it doesnt happen again. Now it seems like...