Search found 5368 matches

by NHE
Sat Jul 11, 2020 9:30 pm
Forum: Ocrevus (Ocrelizumab)
Topic: Does anyone have an experience with Ocrevus that worsens progression?
Replies: 3
Views: 58

Re: Does anyone have an experience with Ocrevus that worsens progression?

motivation wrote:
Sat Jul 11, 2020 8:01 pm
Thank you so much I’m going to look into this. I feel worse off on Ocravus than I did before. Like wtf I thought this was supposed to be some game changer lifesaver. Nope!
This is a brain on PML. viewtopic.php?p=258324#p258324 You don't want this. Nobody does.
by NHE
Sat Jul 11, 2020 7:21 pm
Forum: General Discussion
Topic: TAOPATCH for MS
Replies: 9
Views: 200

Re: TAOPATCH for MS

I wasn't commenting on whether or not the device is actually helpful, just that the company's explanation seems fictitious. Here's an explanation of synaptic signal transduction that's a little closer to reality. I'm also not saying that light can't have a physiological effect. It can. Blue light c...
by NHE
Sat Jul 11, 2020 6:27 pm
Forum: General Discussion
Topic: TAOPATCH for MS
Replies: 9
Views: 200

Re: TAOPATCH for MS

From the Taopatch FAQ page, https://www.taopatch.co/faq ... Really? Neurons use photons to communicate? Why haven't any of my biology textbooks mentioned this? For example, Kandle and Schwartz, Principles of Neuroscience, 5th Edition. https://www.amazon.com/Principles-Neural-Science-Fifth-Kandel/dp...
by NHE
Fri Jul 10, 2020 3:28 am
Forum: Exercise and Physical Therapy
Topic: Exercise improves memory via GPLD1
Replies: 1
Views: 31

Exercise improves memory via GPLD1

An Enzyme That Increases With Exercise Can Improve Memory In Mice, And Maybe People July 9, 20204:42 PM ET https://www.npr.org/sections/health-shots/2020/07/09/889467347/an-enzyme-that-increases-with-exercise-can-improve-memory-in-mice-and-maybe-peop Scientists say they've identified an enzyme that...
by NHE
Thu Jul 09, 2020 4:58 pm
Forum: General Discussion
Topic: Nocebo and Lessebo Effects
Replies: 1
Views: 48

Re: Nocebo and Lessebo Effects

2020 University of Ottawa Brain and Mind Research Institute, Ottawa, ON, Canada; The Ottawa Hospital Research Institute, Ottawa, ON, Canada; Division of Neurology, Department of Medicine, The Ottawa Hospital Nocebo and Lessebo Effects https://pubmed.ncbi.nlm.nih.gov/32563285/ https://fastereft.com/...
by NHE
Thu Jul 09, 2020 3:19 am
Forum: Ocrevus (Ocrelizumab)
Topic: Does anyone have an experience with Ocrevus that worsens progression?
Replies: 3
Views: 58

Re: Does anyone have an experience with Ocrevus that worsens progression?

When I was on Abaugio I felt like things were stable in a sense. Sure I had foot drop. But I felt as though things were manageable. Now today with my 4th infusion of Ocravus, I feel like my right side is weaker and there’s more foot drop. Has anyone else experienced anything bad with this drug? Wha...
by NHE
Sun Jul 05, 2020 9:29 pm
Forum: Natural Approach
Topic: Nervonic acid used for treatment of demyelinating disorders
Replies: 10
Views: 5717

Re: Nervonic acid used for treatment of demyelinating disorders

Naturally Occurring Nervonic Acid Ester Improves Myelin Synthesis by Human Oligodendrocytes Cells. 2019 Jul 29;8(8):786 The dysfunction of oligodendrocytes (OLs) is regarded as one of the major causes of inefficient remyelination in multiple sclerosis, resulting gradually in disease progression. Ol...
by NHE
Sun Jul 05, 2020 6:58 am
Forum: Introductions
Topic: Newly Diagnosed Introduction
Replies: 2
Views: 106

Re: Newly Diagnosed Introduction

Hi Mguncch, After much investigation into the different drug therapies, I have decided to take Tecfidera. I am concerned about how to manage side effects, as well as how to keep a daily routine of good nutrition and health. I look forward to any and all replies. Thank you all in advance! There have ...
by NHE
Sun Jul 05, 2020 6:45 am
Forum: Humor
Topic: Seven alternatives to evidence based medicine
Replies: 1
Views: 83

Re: Seven alternatives to evidence based medicine

Seven alternatives to evidence based medicine (1999) https://www.bmj.com/content/319/7225/1618 Don't forget homeopathy, e.g., oscillococcinum is duck liver diluted by 10 400 . A while back there was a segment on my local NPR station discussing homeopathy. A representative from Boiron was testifying...
by NHE
Fri Jul 03, 2020 3:58 am
Forum: General Discussion
Topic: Nur77
Replies: 1
Views: 55

Re: Nur77

Nur77 Serves as a Molecular Brake of the Metabolic Switch During T Cell Activation to Restrict Autoimmunity Proc Natl Acad Sci U S A. 2018 Aug 21;115(34):E8017-E8026. T cells critically depend on reprogramming of metabolic signatures to meet the bioenergetic demands during activation and clonal exp...
by NHE
Wed Jul 01, 2020 6:18 am
Forum: Vumerity (diroximel fumarate)
Topic: Diroximel fumarate phase III study
Replies: 0
Views: 26

Diroximel fumarate phase III study

Diroximel Fumarate Demonstrates an Improved Gastrointestinal Tolerability Profile Compared With Dimethyl Fumarate in Patients With Relapsing-Remitting Multiple Sclerosis: Results From the Randomized, Double-Blind, Phase III EVOLVE-MS-2 Study CNS Drugs. 2020 Feb;34(2):185-196. Background: Diroximel ...
by NHE
Tue Jun 30, 2020 8:35 am
Forum: Gilenya
Topic: FDA approves generic fingolimod
Replies: 0
Views: 35

FDA approves generic fingolimod

FDA Approves Generic Versions of Gilenya December 6, 2019 https://mymsaa.org/news/fda-approves-generic-gilenya/ On December 5, 2019, the United States Food and Drug Administration (FDA) announced that they had approved the applications from three separate pharmaceutical companies for the first gene...
by NHE
Tue Jun 30, 2020 8:26 am
Forum: Bafiertam (monomethyl fumarate)
Topic: Bafiertam offers a lower dosage vs. Tecfidera
Replies: 0
Views: 26

Bafiertam offers a lower dosage vs. Tecfidera

A lower dose of Bafiertam as compared to Tecfidera may lead to fewer GI side effects, but this has yet to be clinically evaluated. https://mymsaa.org/news/bafiertam-oral-capsules-approved-by-the-fda-for-relapsing-forms-of-ms/ Bafiertam is a “bioequivalent alternative” to Biogen’s Tecfidera® (dimethy...
by NHE
Tue Jun 30, 2020 8:07 am
Forum: Vumerity (diroximel fumarate)
Topic: Vumerity may have less GI side effects.
Replies: 0
Views: 37

Vumerity may have less GI side effects.

There may be less gastrointestinal symptoms with Vumerity as compared to Tecfidera. https://multiplesclerosisnewstoday.com/alks-8700-multiple-sclerosis/ The early findings, on gastrointestinal treatment-emergent adverse events (GI-TEAEs) in 696 participants, were published in the scientific journal ...
by NHE
Tue Jun 30, 2020 6:05 am
Forum: General Discussion
Topic: Two new FDA approvals. Vumerity and Bafiertam
Replies: 1
Views: 71

Re: Two new FDA approvals. Vumerity and Bafiertam

Thanks Frodo. I have established new forums for the two analogs of Tecfidera.

Vumerity: viewforum.php?f=64

Bafiertam: viewforum.php?f=65

Go to advanced search