"It's important to measure what matters most, not make what can most easily be measured matter."
Robert McNamara
Search found 6066 matches
- Wed Mar 27, 2024 8:34 pm
- Forum: Daily Life
- Topic: Quote of the day
- Replies: 23
- Views: 19649
- Wed Mar 27, 2024 6:55 pm
- Forum: Natural Approach
- Topic: Curcumin nanoparticles in neurological disease
- Replies: 1
- Views: 43
Curcumin nanoparticles in neurological disease
Curcumin-loaded nanoparticles: a novel therapeutic strategy in treatment of central nervous system disorders Int J Nanomedicine. 2019 Jun 17:14:4449-4460. Curcumin as a hydrophobic polyphenol is extracted from the rhizome of Curcuma longa. Curcumin is widely used as a dietary spice and a topical me...
- Wed Mar 27, 2024 5:33 am
- Forum: General Discussion
- Topic: The NERVGEN-291 miracle!
- Replies: 10
- Views: 2085
Re: The NERVGEN-291 miracle!
https://stockhouse.com/opinion/independent-reports/2024/03/20/can-nervgen-keep-lid-on-explosive-news Thanks for the article. I agree with the author that it's likely a good sign that NervGen will be offering NVG-291 to patients on the placebo arm in an open label extension. They probably wouldn't e...
- Thu Mar 21, 2024 5:36 pm
- Forum: General Discussion
- Topic: Racial differences in MS pregnancy
- Replies: 0
- Views: 282
Racial differences in MS pregnancy
Disparities by Race in Pregnancy Care and Clinical Outcomes in Women With Multiple Sclerosis: A Diverse Multicenter Cohort Neurology. 2024 Feb 27;102(4):e208100. Background and objectives : Racial disparities exist in both neurologic and obstetric populations, underscoring the importance of evaluat...
- Thu Mar 14, 2024 9:22 pm
- Forum: General Discussion
- Topic: DMD Adverse Events
- Replies: 1
- Views: 413
DMD Adverse Events
Adverse Events Associated With Disease-Modifying Drugs for Multiple Sclerosis: A Multiregional Population-Based Study Neurology. 2024 Feb 13;102(3):e208006. Background and objectives: It is not possible to fully establish the safety of a disease-modifying drug (DMD) for multiple sclerosis (MS) from...
- Tue Mar 12, 2024 12:23 am
- Forum: General Discussion
- Topic: Micro & nanoplatics in arterial plaques
- Replies: 0
- Views: 293
Micro & nanoplatics in arterial plaques
A recent report discovered a surprising amount of micro and nanoplastics in bottled water. https://www.npr.org/2024/01/10/1223730333/bottled-water-plastic-microplastic-nanoplastic-study Now we learn that these plastics are not inert and can also be found to accumulate in the vascular system contribu...
- Sun Mar 10, 2024 11:53 pm
- Forum: Diet
- Topic: Neuroprotective effects of berries
- Replies: 0
- Views: 1145
Neuroprotective effects of berries
Neuroprotective effects of berry fruits on neurodegenerative diseases Neural Regen Res. 2014 Aug 15;9(16):1557-66. Recent clinical research has demonstrated that berry fruits can prevent age-related neurodegenerative diseases and improve motor and cognitive functions. The berry fruits are also capa...
- Fri Mar 08, 2024 8:03 pm
- Forum: General Discussion
- Topic: Saccharomyces boulardii probiotic
- Replies: 8
- Views: 896
Re: Saccharomyces boulardii probiotic
This is the Saccharomyces boulardii probiotic I just ordered and received. 200 billion CFU , priced right at $24 - an exceptional value. https://www.amazon.com/dp/B0CLKF5NWP Some of the reviews aren't so good. I bought these to make fermented probiotic apple juice. After 48 hours there is zero ferm...
- Fri Mar 08, 2024 7:00 am
- Forum: General Discussion
- Topic: Saccharomyces boulardii probiotic
- Replies: 8
- Views: 896
Re: Saccharomyces boulardii probiotic
Keep in mind while billions of anything sounds like a lot, the population of bacteria in the gut is in the multiple trillions . Just for clarity, Saccharomyces boulardii is a yeast. The study posted used a S. boulardii supplement with just 1010 CFUs. In addition, I read a paper some time ago that s...
- Thu Mar 07, 2024 9:37 pm
- Forum: Diet
- Topic: Fasting & Neurodegenerative Disease
- Replies: 0
- Views: 500
Fasting & Neurodegenerative Disease
Perspective: The Impact of Fasting and Caloric Restriction on Neurodegenerative Diseases in Humans Adv Nutr. 2024 Mar 1:100197. Neurodegenerative diseases (ND) are characterized by the progressive functional and structural denaturation of neurons in the central and peripheral nervous systems. Despi...
- Thu Mar 07, 2024 9:14 pm
- Forum: General Discussion
- Topic: Saccharomyces boulardii probiotic
- Replies: 8
- Views: 896
- Mon Mar 04, 2024 9:17 am
- Forum: General Discussion
- Topic: RE: CLEMASTINE FUMARATE RESTORES MYELIN IN M.S
- Replies: 7
- Views: 1768
Re: Clemastine Trial Halted Following Increased Disability Accumulation in PPMS!
More info... https://www.neurologylive.com/view/clemastine-arm-trap-ms-trial-halted-following-increased-disability-accumulation-progressive-ms In the trial, investigators halted the clemastine arm because of 3 participants who increased in disability 5-times faster than compared with 18-month “basel...
- Sun Mar 03, 2024 11:39 am
- Forum: General Discussion
- Topic: Coronavirus (COVID-19) Research
- Replies: 185
- Views: 70418
Re: Coronavirus (COVID-19) Research
Study Reveals Side Effects of COVID-19 Vaccines COVID-19 vaccines produce some very serious side effects such as Guillain Barré syndrome, but for the most part these are rare. Terry Graedon - February 29, 2024 https://www.peoplespharmacy.com/articles/study-reveals-side-effects-of-covid-19-vaccines ...
- Sun Feb 25, 2024 4:50 am
- Forum: Drug Pipeline
- Topic: Summary of the pipeline
- Replies: 437
- Views: 216757
Re: AICAR
This is from 2019. What Athletes Should Know About AICAR and Other Prohibited AMP Activated Protein Kinase Activators Education, Spirit of Sport / November 14, 2019 https://www.usada.org/spirit-of-sport/education/aicar-and-other-prohibited-amp-activated-protein-kinase-activators/ In recent years, AI...
- Sun Feb 25, 2024 3:55 am
- Forum: Drug Pipeline
- Topic: Summary of the pipeline
- Replies: 437
- Views: 216757
Frexalimab phase 2 trial
Inhibition of CD40L with Frexalimab in Multiple Sclerosis N Engl J Med. 2024 Feb 15;390(7):589-600. Background : The CD40-CD40L costimulatory pathway regulates adaptive and innate immune responses and has been implicated in the pathogenesis of multiple sclerosis. Frexalimab is a second-generation a...