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DIM wrote: ↑Sun May 19, 2024 1:19 pm 20 mg/kg/d is too much ALA and costs a lot.
They don't mention what type of ALA they use.

Unless a paper specifies R-Lipoic Acid or Na-R-Lipoate, I think it's safe to assume that Alpha Lipoic Acid refers to racemic R/S-Lipoic Acid.

The dual face of microglia (M1/M2) as a potential target in the protective effect of nutraceuticals against neurodegenerative diseases Front Aging. 2023 Sep 6:4:1231706. The pathophysiology of different neurodegenerative illnesses is significantly influenced by the polarization regulation of microg...

Remyelinating activities of Carvedilol or alpha lipoic acid in the Cuprizone-Induced rat model of demyelination Int Immunopharmacol. 2023 May:118:110125. Multiple sclerosis (MS) is a complex and multifactorial neurodegenerative disease with unknown etiology, MS is featured by multifocal demyelinate...

DIM wrote: ↑Sun May 12, 2024 8:48 pm https://neurosciencenews.com/myelin-rep ... ogy-26027/

https://www.cell.com/cell/abstract/S009 ... 24)00400-8

Healthy Lifestyle and Cognition in Older Adults With Common Neuropathologies of Dementia JAMA Neurol. 2024 Mar 1;81(3):233-239. Importance : A healthy lifestyle is associated with better cognitive functioning in older adults, but whether this association is independent of the accumulation of dement...

Diet, Pace of Biological Aging, and Risk of Dementia in the Framingham Heart Study Ann Neurol. 2024 Feb 26. Objective : People who eat healthier diets are less likely to develop dementia, but the biological mechanism of this protection is not well understood. We tested the hypothesis that healthy d...

Prediction of disease activity and treatment failure in relapsing-remitting MS patients initiating daily oral DMTs Mult Scler. 2024 Mar 29:13524585241240653. Background : Limited data exist regarding treatment response prediction to oral disease-modifying therapies (DMTs) in multiple sclerosis (MS)...

Thanks NHE this is interesting. I used to take LDN many years ago! I could use some chronic pain relief all these years later. Not the same reason that I was taking it back then of course. Yes, I'm looking into it for the neuropathy in my feet. It feels like they were rubbed with nettle leaf and th...

Low Dose Naltrexone (LDN) Provides Surprising Pain Relief What do you know about low dose naltrexone (LDN) for pain? This very old drug might help some people with osteoarthritis and other conditions. Joe Graedon - April 29, 2024 https://www.peoplespharmacy.com/articles/low-dose-naltrexone-ldn-prov...

Gut Microbiota Linked to Stroke Severity The composition of the gut microbiota influences the likelihood of severe strokes. A healthy digestive ecology also reduces the risk of AD. Terry Graedon - April 25, 2024 https://www.peoplespharmacy.com/articles/gut-microbiota-linked-to-stroke-severity We ha...

"Sometimes time is not a healer Sometimes time is a silver fool Sometimes time is the true deceiver It’s taken me some time And I give you some time Sometimes time is not a healer Sometimes time is my greatest foe Sometimes time shows a true believer Sometimes, not all the time Sometimes I don’...

Why Don’t Vitamin D Supplements Work as Expected? Vitamin D supplements are extremely popular. Millions swallow little golden pills daily. But why are clinical trials producing such disappointing results? https://www.peoplespharmacy.com/articles/why-dont-vitamin-d-supplements-work-as-expected If yo...

Contrary to the video presentation, I had a different experience with lemon juice. The video claims that lemon juice will help dissolve a kidney stone. However, many years ago I had a kidney stone and found similar information on the net. I bought a bagful of lemons. I drank a glass of fresh squeeze...

People considering liraglutide may wish to read the prescribing information. This drug can have serious side effects including thyroid cancer and pancreatitis. https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/022341lbl.pdf • Thyroid C-cell tumors in animals: Human relevance unknown. Counsel...

Coca-Cola has become engrained in the culture of rural Mexico. In small towns like San Cristóbal roughly half the population has diabetes. Death from diabetes is common. The cause, Coca-Cola. The average person drinks 2L/day. This is 222 lb of sugar per year! https://www.youtube.com/watch?v=hqnUohxX...