This Is MS Multiple Sclerosis Knowledge & Support Community

Harryz, yes, I'll have to deal with it in my own way. We ALL have our crosses to bear, I suppose. As for SPMS or PPMS, I don't know the mechanism of disease but I think back to the 5-yr old girl with an aggressive form of MS. http://www.thisisms.com/modules.php?name=Forums&file=viewtopic&t=5...

Optimist I dunno why the link works on Braintalk and not here, but I suspect that the /...../ in the link were placeholders on Braintalk for the full link, while when I cut and pasted the link it was pasted at /...../. That's the only explanation I can think of. Harryz I think there was a misunderst...

Finn The posting times are weird, but I'm in not in the U.S. or Europe so my posts will appear to be at stange times relative to these areas. My guess is the interpretation of the data rests on its statistical significance. Freedman noticed a trend to higher relapse rates of the high natalizumab gro...

Finn Thanks for the tip on how to post links. I was aware that Dr. Freedman's comments were about the Natalizumab P2 trial, and indeed I quoted the P2 trial NEJM paper which contradicted Dr. Freedman's comments. Again, it 'appears' that Dr. Freedman is drawing a conclusion on data that were NOT stat...

Last post on this issue from me, just to set the record straight IMO, and I'll give you the last word. But let me say that, I'm sure that you (Harryz) have done a lot for this board and others, and will continue to do so. I am not in a contest with you, nor do I want to be. You and I have different ...

Finn, on the rebound effect I note that your 2nd citation suggesting this problem was published in MAY 2002 as conference coverage of the 2002 AAN Conference. Yet the Phase 2 trial was NOT published in a peer-reviewed journal until JANUARY 2003. The NJEM paper on the Phase 2 trial is at: http://cont...

Harryz Sorry about the link. I simply reposted that info from the Braintalk forum. I should have checked it. Perhaps the fact that I am using her as a reference by reading her posts and that she has the same doubts about Tysabari that I and many others have, is reason for Observer to cast doubt on h...

Finn Looks like you and I, and I'm sure Harryz, agree on one thing: the sooner they get the 2yr data out, the better! The companies say they'll get the data out at ASN in April, but I'd guess they will have it compiled sooner and perhaps release it. Lets hope so, as you state and I agree, there is t...

Harryz Since we are talking about the credibility of this poster and the snippet about 'privy to 2yr data', lets look at something she's posted on Braintalk. [For the record, I don't post there, but it does make an interesting read - seems much different in some ways from this forum.] I think we're ...

A poster on Braintalk forum has indicated that the webcast transcript is available now. Here is the webcast link - you can launch the multimedia presentation at the bottom of this link. I understand a transcript of the Q&A will be on-line next Monday. http://www.msleaders.org/ms-leaders...mplica...

Tysabri SEEMS to be indicated for any form of MS which has relapses, which means that SPMS and others might be viable candidates. Obviously ALL patients should check with their neurologists on this, but there has been a lot of, I believe, possibly wrong information posted that it is only for RRMS. P...

Harryz - more hearsay. An 'MS Professional' who is privy to something. That's simply wrong (on the Professional's part) to say things like that and NOT give details. "I've got a secret" How childish of this person on the Braintalk forum, and this person further claims that erroneious infor...

Here is the webcast link - you can launch the multimedia presentation at the bottom of this link. I understand a transcript of the Q&A will be on-line next Monday.

http://www.msleaders.org/ms-leaders/liv ... ations.asp

I have not yet listened to the presentation.

Harryz

Lets just hope they get the 2 yr data out quickly. Whatever it says, I'm sure we'll find something to disagree about.

You obviously have NOT read the links, as none are from Company press releases. Or is there some grand conspiracy between Biogen Idec and The North County Times of San Diego? Good grief! Why are you equating a MS doc, who is speaking to an audience of MS professionals and gave his opinion about Tysa...