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When I stoppeed due to the withdrawl from the market I had a major flareup and am still not recovered to where i was at that time. there is research on the "rebound effect" http://ms.about.com/b/2011/02/09/the-ty ... effect.htm
http://www.news-medical.net/news/2007/09/13/29789.aspx

I have been on tysabri since the first phase 2 trial and have stayed on as much as was available. my biggest fear is stopping it. klkm