Search found 61 matches

by MSbro
Fri Apr 29, 2016 6:48 am
Forum: General Discussion
Topic: New injectable multiple sclerosis drug given go-ahead
Replies: 1
Views: 833

Re: New injectable multiple sclerosis drug given go-ahead

A once-monthly injection for multiple sclerosis from Biogen and AbbVie has been recommended for approval by European regulators, paving the way for its launch in the coming months...Read more - http://www.ms-uk.org/MSnews Hmmm..another monoclonal antibody...sure hope this drug doesn't have half the...
by MSbro
Wed Apr 27, 2016 7:32 am
Forum: MS Etiology and Pathogenesis
Topic: MS: A Functional Disorder
Replies: 13
Views: 2118

Re: MS: A Functional Disorder

Another thought that occurred to me. People with MS are known to have an elevated ACE level (more typically associated in people with sarcoidosis). The high ACE level is indicator of a problem with the renin-angiotensin system which regulates fluid movement within the body (this is my low level und...
by MSbro
Tue Apr 26, 2016 8:42 am
Forum: MS Etiology and Pathogenesis
Topic: MS: A Functional Disorder
Replies: 13
Views: 2118

Re: MS: A Functional Disorder

Vesta, I hear what you are saying and I am VERY happy that the treatment you are using works for you. But because MS appears to be so complex someone else trying this may not get any benefit at all. And I realize that peer reviewed studies are expensive and time consuming but how else can one scient...
by MSbro
Tue Apr 26, 2016 6:16 am
Forum: MS Etiology and Pathogenesis
Topic: MS: A Functional Disorder
Replies: 13
Views: 2118

Re: MS: A Functional Disorder

All of your points are well presented but until anyone can "prove" any of the many current possible theories as to the cause of MS, then we will continue to have many different opinions on this truly complex disease. Treatments that work for some patients do absolutely nothing for the next one and v...
by MSbro
Sat Apr 23, 2016 4:58 am
Forum: Ocrevus (Ocrelizumab)
Topic: ‘No evidence of disease activity’ for Ocrelizab patients
Replies: 2
Views: 2688

Re: ‘No evidence of disease activity’ for Ocrelizab patients

‘No evidence of disease activity’ for multiple sclerosis patients on Ocrelizumab Patients with multiple sclerosis (MS) taking Ocrelizumab are more likely to achieve no evidence of disease activity (NEDA) than those taking beta interferon, researchers from the pivotal OPERA I and OPERA II phase III ...
by MSbro
Tue Apr 05, 2016 5:54 am
Forum: General Discussion
Topic: Why should I take DMDs? Not being rhetorical (x-post MSWorld
Replies: 16
Views: 1854

Re: Why should I take DMDs? Not being rhetorical (x-post MSW

As one can read from all the responses so far, what can work for one person does nothing for the next. You can take a DMD and end up having all kinds of attacks or it may reduce the number. Despite all the advertising by the drug companies who make these medications it still has not been proven that...
by MSbro
Thu Feb 18, 2016 8:18 pm
Forum: General Discussion
Topic: Norwegian Supreme Court: MMR Vaccine caused MS
Replies: 11
Views: 1518

Re: Norwegian Supreme Court: MMR Vaccine caused MS

Yes, once the courts get involved in medical cases, anything is possible
by MSbro
Tue Dec 22, 2015 5:04 pm
Forum: Ocrevus (Ocrelizumab)
Topic: Roche drug ocrelizumab clears final hurdle
Replies: 5
Views: 3279

Re: Roche drug ocrelizumab clears final hurdle

Another monoclonal antibody drug that plays with the immune system. Wonder how many cases of PML this drug will end up giving to MS patients?
by MSbro
Mon Dec 21, 2015 6:48 am
Forum: General Discussion
Topic: Another clue in understanding multiple sclerosis?
Replies: 10
Views: 1342

Re: Another clue in understanding multiple sclerosis?

http://ccsviinms.blogspot.com/2015/06/pictures-worth-some-words.html the isnvd is looking at this. Kipnis is the keynote speaker in NYC next year. http://ccsviinms.blogspot.com/2015/12/moving-forward.html Getting there, cheer/Joan Thanks for the info, Cheer. Not very comforting to read that the doc...
by MSbro
Sun Dec 20, 2015 5:22 pm
Forum: General Discussion
Topic: Another clue in understanding multiple sclerosis?
Replies: 10
Views: 1342

Re: Another clue in understanding multiple sclerosis?

Cheer, It looks like a very big longshot trying to tie together all of these little bits of info from the MS mouse research. This kind of investigation can take years of work but then again, after decades and decades of MS research resulting in no cause or cure, what's another 10 years or so! Makes ...
by MSbro
Sun Dec 20, 2015 3:38 pm
Forum: General Discussion
Topic: Another clue in understanding multiple sclerosis?
Replies: 10
Views: 1342

Re: Another clue in understanding multiple sclerosis?

Hi. That might be a bit harsh. The reaction can be observed. Its a pity they defined the lymphatic system that way. Cheerleader did note some Israeli work that found the lymphatic system extended into the brain. That tipped 100 years of thinking on its head so little connections like this can be he...
by MSbro
Sun Dec 20, 2015 11:29 am
Forum: General Discussion
Topic: Another clue in understanding multiple sclerosis?
Replies: 10
Views: 1342

Re: Another clue in understanding multiple sclerosis?

Done on the mouse model of MS....which I've read really isn't human MS at all. So how accurate can this research be other than finding something different in mouse MS?
by MSbro
Thu Dec 17, 2015 6:21 am
Forum: General Discussion
Topic: Research suggests MS could be triggered by brain cell death
Replies: 2
Views: 941

Re: Research suggests MS could be triggered by brain cell de

I read something a while ago about Prineas and Barnett's work. They did an autopsy on a young lady who died quite quickly after a severe MS attack which severely affected her lungs. The autopsy was done almost immediately after death and they found no evidence of immune system activity at all which ...
by MSbro
Sun Nov 29, 2015 5:48 am
Forum: General Discussion
Topic: Detecting scientific fraud
Replies: 1
Views: 866

Re: Detecting scientific fraud

Stanford researchers uncover patterns in how scientists lie about their data When scientists falsify data, they try to cover it up by writing differently in their published works. A pair of Stanford researchers have devised a way of identifying these written clues. http://news.stanford.edu/news/201...
by MSbro
Thu Nov 26, 2015 7:16 am
Forum: General Discussion
Topic: Throbbing
Replies: 14
Views: 1033

Re: Throbbing

Yes I do have MS, and I am at my wits end lol I wake up with this feeling and go to bed with it! I don't know if I should look into finding another doctor to look into it?!? Or what road to take! If possible see if you can locate a Pain Clinic that operates in your area and get referred to it. Thes...