Search found 21 matches
- Wed Jan 09, 2019 9:11 am
- Forum: MS Etiology and Pathogenesis
- Topic: Myelocortical MS (MCMS)
- Replies: 6
- Views: 2555
Re: Thanks to MS-UK: New type of MS discovered
These are big news. First of all, because 12% of patients have damage in the WM without demyelination. So much for the autoimmune demyelination theories. Your statement is not scientifically supportable. This subset of patients may be able to re-myelinate white matter more efficiently. And AI demye...
- Wed Jan 09, 2019 8:57 am
- Forum: General Discussion
- Topic: New lesion despite being PPMS or SPMS
- Replies: 14
- Views: 3715
Re: New lesion despite being PPMS or SPMS
Try nicotinic acid, the B3 that makes you flush.
Most people it only takes 50mg, for me it takes 1000. Klenner said 750 was usually necessary for MS persons to flush back in the 70s.
It's completely safe, in fact it is the single most effective cholesterol medication ever.
Most people it only takes 50mg, for me it takes 1000. Klenner said 750 was usually necessary for MS persons to flush back in the 70s.
It's completely safe, in fact it is the single most effective cholesterol medication ever.
- Wed Jan 09, 2019 8:50 am
- Forum: MS Etiology and Pathogenesis
- Topic: Wolfson Institute of Preventive Medicine. EBV is MS cause.
- Replies: 1
- Views: 1164
Re: Wolfson Institute of Preventive Medicine. EBV is MS cause.
EBV and the Human Herpes Virus family activate the epigenetic pathway for the MS genetically prone. The EBV does not cause MS. An inflammatory cascade initiated by CD20+ B cells that recruits T cells to attack myelin, and creates multiple inflammatory cytokine and protein cascades that prevent corre...
- Wed Jan 09, 2019 8:44 am
- Forum: Ocrevus (Ocrelizumab)
- Topic: Ocrevus is a Wonder Drug for MS
- Replies: 9
- Views: 6449
Re: Ocrevus is a Wonder Drug for MS
"It is the ONLY THERAPY to ever do #5 and #6" Not true - there are now other safe therapies doing #5 and #6. Which clinically documented? Because you're statement is factually incorrect. Ocrevus is the ONLY treatment to stop progression and also recover LOST function, unless you are talki...
- Wed Jan 09, 2019 8:33 am
- Forum: Regimens
- Topic: to add to jimmyleg's info/thiamine B1
- Replies: 23
- Views: 14144
Re: to add to jimmyleg's info/thiamine B1
NAD+ reverses animal models of autoimmune diseases
https://www.prohealth.com/library/can-a ... very-86540
https://www.prohealth.com/library/can-a ... very-86540
- Wed Jan 09, 2019 8:29 am
- Forum: Regimens
- Topic: to add to jimmyleg's info/thiamine B1
- Replies: 23
- Views: 14144
Re:
Jimmy...What form of B1 are you taking? Oral? I'm taking benfotiamine at present and starting im injections today when it arrives. Yes klenner's info is dated but if one looks for the logic it's there I believe(albeit simplistic) I don't think they expected any "layman reasearch" in those...
Re: Ocrevus
Hi there. My husband was diagnosed with RRMS back in May, but now the doctor thinks he may have PPMS. He suggested that we look into Ocrevus. I have been reading about it a little and it sounds scary (could cause cancer, could lead to death), but it's the only MS drug out there that treats PPMS. An...
- Wed Nov 21, 2018 5:35 pm
- Forum: Drug Pipeline
- Topic: The Misfortune of MS Drugs
- Replies: 6
- Views: 4860
Re: The Misfortune of MS Drugs
Nicotinic acid in high doses
- Wed Nov 21, 2018 5:31 pm
- Forum: Ocrevus (Ocrelizumab)
- Topic: Ocrevus is a Wonder Drug for MS
- Replies: 9
- Views: 6449
Re: Ocrevus is a Wonder Drug for MS
but is it any better then rituximab? My doc wants me to go on rituximab and keep taking avonex as the insurance company wuill keep paying for both. Short answer = yes Long answer = 1. It is 100% human versus the human/mouse chimeric rituxan 2. It has a higher binding affinity for CD20 expressing b ...
- Wed Oct 31, 2018 4:54 am
- Forum: General Discussion
- Topic: Fed up PRMS looking for anything !!
- Replies: 14
- Views: 2471
Re: Fed up PRMS looking for anything !!
My own experience with only 1000 mg of nicotine acid because that's actually how much it takes me to flush now is that it completely removed my need to take Skelaxin for the pain and has also increased my stamina such that prior to diagnosis I could barely get out of my car and now I can mow my 2/3 ...
- Wed Oct 31, 2018 4:51 am
- Forum: General Discussion
- Topic: Fed up PRMS looking for anything !!
- Replies: 14
- Views: 2471
Re: Fed up PRMS looking for anything !!
All the clinical data shows that ocrevus takes 2 years to show any efficacy at stopping progression of the disease give it some time. Emerging data from some of the longer Trials of ocrevus have shown that it has actually helped some patients regain lost cognitive and physical function You could als...
- Wed Oct 31, 2018 4:48 am
- Forum: General Discussion
- Topic: Link Between Gut Flora and Multiple Sclerosis Discovered
- Replies: 19
- Views: 4020
Re: Link Between Gut Flora and Multiple Sclerosis Discovered
Of note memory B cells are actually implicated in Guillain-Barre syndrome which is another demyelinating disease
https://www.ncbi.nlm.nih.gov/m/pubmed/28284328/
Memory B cells in Guillain-Barré syndrome.
https://www.ncbi.nlm.nih.gov/m/pubmed/28284328/
Memory B cells in Guillain-Barré syndrome.
- Wed Oct 31, 2018 4:45 am
- Forum: General Discussion
- Topic: Link Between Gut Flora and Multiple Sclerosis Discovered
- Replies: 19
- Views: 4020
Re: Link Between Gut Flora and Multiple Sclerosis Discovered
It actually makes sense that in Ms part of the pathology is that B cells activate T-cells to become pathogenic because in some types of immunizations like tetanus for example the B cells Ferry the toxoid to the T cell to train the T-cell to recognize the toxoid as something to create an antigen agai...
- Wed Oct 31, 2018 4:42 am
- Forum: General Discussion
- Topic: Link Between Gut Flora and Multiple Sclerosis Discovered
- Replies: 19
- Views: 4020
Re: Link Between Gut Flora and Multiple Sclerosis Discovered
Actually, it is CD20 b cells that cause an inflammatory cascade initially, resulting in demyelination and abnormal re-myelination. New evidence has identified that B cells in persons with MS activate T-cells to become pathogenic so the result is many T cells are found in some of the larger lesions a...
- Wed Oct 31, 2018 4:33 am
- Forum: Ocrevus (Ocrelizumab)
- Topic: Second Infusion two weeks away, I feel like death? Any other
- Replies: 12
- Views: 7541
Re: Second Infusion two weeks away, I feel like death? Any o
@ anonymouse
Ocrevus has been clinically shown to stop progression, and in emerging data, after 4+ years it has been shown to actually help some patients recover LOST function, physical and cognitive.
Google it
Ocrevus has been clinically shown to stop progression, and in emerging data, after 4+ years it has been shown to actually help some patients recover LOST function, physical and cognitive.
Google it