Search found 11847 matches

by jimmylegs
Sat Apr 20, 2019 1:45 pm
Forum: Drug Pipeline
Topic: 2019 murine study: Sob-AM2 for myelin repair
Replies: 0
Views: 3

2019 murine study: Sob-AM2 for myelin repair

Myelin repair stimulated by CNS-selective thyroid hormone action (2019) https://europepmc.org/abstract/MED/30996143 Abstract Oligodendrocyte processes wrap axons to form neuroprotective myelin sheaths, and damage to myelin in disorders, such as multiple sclerosis (MS), leads to neurodegeneration an...
by jimmylegs
Sat Apr 20, 2019 6:31 am
Forum: General Discussion
Topic: Would TiMS users benefit from a Health Promotion section?
Replies: 6
Views: 301

Re: Would TiMS users benefit from a Health Promotion section?

more votes pls! interesting: Lifestyle, medication and socio-demographic determinants of mental and physical health-related quality of life in people with multiple sclerosis (2016) https://bmcneurol.biomedcentral.com/articles/10.1186/s12883-016-0763-4 Abstract Background Health-related quality of li...
by jimmylegs
Fri Apr 19, 2019 3:22 pm
Forum: Natural Approach
Topic: uric acid
Replies: 159
Views: 35162

2013 review: hepatic/hyperammonemic encephalopathy

can't get all the pieces in one article so far, but this one at least links encephalopathy, ammonia and ms: Current pathogenetic aspects of hepatic encephalopathy and noncirrhotic hyperammonemic encephalopathy (2013) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545226/ "Hepatic encephalopathy is a ...
by jimmylegs
Fri Apr 19, 2019 12:32 pm
Forum: Natural Approach
Topic: uric acid
Replies: 159
Views: 35162

2017 case: urea cycle disorder and MS misdx

hmm interesting. Urea cycle disorder misdiagnosed as multiple sclerosis: a case report and review of the literature (2017) https://europepmc.org/articles/pmc5882056 "Urea cycle disorders are a group of inborn errors of metabolism caused by dysfunction of any of the six enzymes or two transport prote...
by jimmylegs
Fri Apr 19, 2019 10:21 am
Forum: Natural Approach
Topic: uric acid
Replies: 159
Views: 35162

2018 study: u-shaped uric acid and mortality

U‐Shaped Association Between Serum Uric Acid Levels With Cardiovascular and All‐Cause Mortality in the Elderly: The Role of Malnourishment (2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850189/ "...Over a median follow‐up of 5.8 years, there were 16 439 all‐cause and 3877 CVD‐related deaths. ...
by jimmylegs
Fri Apr 19, 2019 5:13 am
Forum: Natural Approach
Topic: uric acid
Replies: 159
Views: 35162

2018 study: serum UA in PwMS using DMT

Assessment of Serum Uric Acid Levels in Multiple Sclerosis during Disease-Modifying Treatment (2018) https://pdfs.semanticscholar.org/d6bd/2dbf5cd8fe8feea6c436bdd26e0d6294166a.pdf "Results: Serum UA levels of MS patients were significantly lower (4.2 ± 1.1 mg/dl) when compared with control group (4...
by jimmylegs
Fri Apr 19, 2019 4:49 am
Forum: Natural Approach
Topic: uric acid
Replies: 159
Views: 35162

1977 study: low zinc intake reduces serum ua

another one linking low zinc intake with reduced uric acid levels. Effect of Low Zinc Intake and Oral Contraceptive Agents on Nitrogen Utilization and Clinical Findings in Young Women (1977) FRANCES M. H https://bit.ly/2XrVYmg "In a previous paper we reported that serum, urine and fecal zinc levels ...
by jimmylegs
Wed Apr 17, 2019 7:01 am
Forum: Introductions
Topic: Hello
Replies: 282
Views: 23971

Re: Hello

way to go!!! (*) (*) (*) (*) (*)
by jimmylegs
Wed Apr 17, 2019 6:08 am
Forum: Undiagnosed
Topic: B12 question
Replies: 32
Views: 441

Re: B12 question

no probs, that's why we're here :D
by jimmylegs
Tue Apr 16, 2019 7:38 pm
Forum: Undiagnosed
Topic: B12 question
Replies: 32
Views: 441

Re: B12 question

it was a pain for sure and all along as i was getting sicker i thought i was actually doing the right thing diet-wise. like a chump. luckily you don't have to learn it all at once. a quality diet, a quality multi vit/min, some omega 3s and vit d3 (with mag of course) as needed would be a pretty well...
by jimmylegs
Tue Apr 16, 2019 12:00 pm
Forum: Undiagnosed
Topic: B12 question
Replies: 32
Views: 441

Re: B12 question

that is great that your network is helping out with the dietitian quest, hope there's success soon. as for supplements, i basically read alot. trial and error over time. in the earliest days i knew b12 wasn't doing the trick on its own any more, so i started branching out to b complex. at some point...
by jimmylegs
Tue Apr 16, 2019 4:24 am
Forum: Undiagnosed
Topic: B12 question
Replies: 32
Views: 441

Re: B12 question

when you eat anything you're likely eating microplastics Low levels of microplastics (MP) in wild mussels indicate that MP ingestion by humans is minimal compared to exposure via household fibres fallout during a meal (2018) https://www.sciencedirect.com/science/article/pii/S0269749117344445 breathi...
by jimmylegs
Mon Apr 15, 2019 6:23 pm
Forum: Undiagnosed
Topic: B12 question
Replies: 32
Views: 441

Re: B12 question

i did, but i REALLY enjoyed the half a veggie wrap i had with them. pretty bummed about reports they've since taken that off the menu :( but i will go back for some more oysters. they have a 'buck a shuck' special every afternoon at a place near here. in the meantime i just take a 50mg zinc pill mon...
by jimmylegs
Mon Apr 15, 2019 3:19 pm
Forum: Undiagnosed
Topic: B12 question
Replies: 32
Views: 441

Re: B12 question

ok sounds like a good plan. fwiw i don't know if your shellfish routine includes oysters, but for zinc they blow all other shellfish out of the figurative water. https://ndb.nal.usda.gov/ndb/nutrients/report?nutrient1=309&nutrient2=&nutrient3=&fg=15&max=25&subset=0&offset=0&sort=c&totCount=264&measu...
by jimmylegs
Mon Apr 15, 2019 8:18 am
Forum: General Discussion
Topic: Olfactory dysfunction
Replies: 1
Views: 33

Re: Olfactory dysfunction

Oral zinc aspartate treats experimental autoimmune encephalomyelitis (2014) https://link.springer.com/article/10.1007/s10534-014-9786-8 The essential trace element zinc plays a critical role in the regulation of immune homeostasis. Zinc deficiency or excess can cause severe impairment of the immune...