Search found 11999 matches

by jimmylegs
Sun Jan 19, 2020 6:43 am
Forum: Natural Approach
Topic: all things magnesium
Replies: 228
Views: 42239

Re: all things magnesium

Severe hypermagnesemia induced by magnesium oxide ingestion: a case series (2019) fft: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361089/ Abstract Hypermagnesemia is generally considered an exceptional iatrogenic condition usually caused by magnesium-containing cathartics. In particular, this co...
by jimmylegs
Wed Jan 15, 2020 4:33 pm
Forum: Introductions
Topic: Hello
Replies: 292
Views: 29493

Re: Hello

hope you're feeling better! how's the rest of your regular maintenance regimen going, other than the rebif and the current cough syrup, pain killers and vinegar?
by jimmylegs
Wed Dec 11, 2019 5:34 pm
Forum: Natural Approach
Topic: zinc and MS
Replies: 79
Views: 32117

Re: zinc and MS

interesting title encounter: Zinc deficiency and its repletion following liver transplantation in humans. https://www.ncbi.nlm.nih.gov/pubmed/8826662 (related older topic i have yet to reread in detail https://www.thisisms.com/forum/viewtopic.php?t=6906) stream-of-consciousness follow-up search titl...
by jimmylegs
Tue Dec 03, 2019 9:41 am
Forum: Natural Approach
Topic: all things vitamin D
Replies: 1061
Views: 118653

Re: all things vitamin D

The Latest Evidence from Vitamin D Intervention Trials for Skeletal and Non-skeletal Outcomes (2019) https://link.springer.com/article/10.1007/s00223-019-00616-y Vitamin D has long been considered a central part of the treatment paradigm for osteoporosis. Initial studies in high-risk populations wi...
by jimmylegs
Mon Nov 25, 2019 3:17 pm
Forum: Friends and Family
Topic: no more-there's nothing left
Replies: 13
Views: 3531

Re: no more-there's nothing left

yep and everyone is free to complain about the results of self care inaction or or celebrate benefits of due diligence as applicable.
have at it :)
by jimmylegs
Sat Nov 23, 2019 8:16 am
Forum: Friends and Family
Topic: no more-there's nothing left
Replies: 13
Views: 3531

Re: no more-there's nothing left

pop quiz:

select one.

a fundamental requirement of life on earth:
a) surgery
b) antibiotics
c) essential nutrition

related reading:

Essential chemistry for biochemists
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869253/

enjoy :)
by jimmylegs
Mon Nov 18, 2019 4:40 pm
Forum: Friends and Family
Topic: no more-there's nothing left
Replies: 13
Views: 3531

Re: no more-there's nothing left

so short answer 'no'? ;)
by jimmylegs
Sat Nov 09, 2019 10:45 am
Forum: Natural Approach
Topic: zinc and MS
Replies: 79
Views: 32117

Re: zinc and MS

not ms, but Amyloid plaques arise from zinc-enriched cortical layers in APP/PS1 transgenic mice and are paradoxically enlarged with dietary zinc deficiency (2007) https://www.sciencedirect.com/science/article/abs/pii/S0306452207011608 The ZnT3 zinc transporter is uniquely expressed in cortical gluta...
by jimmylegs
Sat Nov 09, 2019 10:17 am
Forum: Natural Approach
Topic: zinc and MS
Replies: 79
Views: 32117

Re: zinc and MS

parked for future review/study Zinc transporter 3 (ZnT3) and vesicular zinc in central nervous system function (2017) https://www.ncbi.nlm.nih.gov/pubmed/28624432 Zinc transporter 3 (ZnT3) is the sole mechanism responsible for concentrating zinc ions within synaptic vesicles in a subset of the brain...
by jimmylegs
Sat Nov 09, 2019 7:51 am
Forum: Natural Approach
Topic: zinc and MS
Replies: 79
Views: 32117

Re: zinc and MS

Zinc transporter 3 (ZnT3) gene deletion reduces spinal cord white matter damage and motor deficits in a murine MOG-induced multiple sclerosis model (2016) https://www.sciencedirect.com/science/article/pii/S0969996116301589 The present study aimed to evaluate the role of zinc transporter 3 (ZnT3) on...
by jimmylegs
Sat Nov 09, 2019 4:22 am
Forum: Natural Approach
Topic: zinc and MS
Replies: 79
Views: 32117

Re: zinc and MS

i'm so irritated reading posts from a year ago. note to self. again. do not give your health second priority. i should have pushed for the specifics i needed sooner and more often. The emerging role of serum zinc in motor disability and radiological findings in patients with multiple sclerosis (2019...
by jimmylegs
Tue Oct 29, 2019 10:26 am
Forum: Natural Approach
Topic: all things vitamin D
Replies: 1061
Views: 118653

2020: proposed paradigm shift

Randomized clinical trials of oral vitamin D supplementation in need of a paradigm change: The vitamin D autacoid paradigm (2020) https://www.sciencedirect.com/science/article/pii/S0306987719309715 Epidemiological studies highlight the negative correlation between vitamin D levels and the incidence...
by jimmylegs
Mon Oct 28, 2019 3:37 pm
Forum: Daily Life
Topic: icky lab results
Replies: 0
Views: 758

icky lab results

welp i've been feeling a bit on the crap side and some of the answers are coming in now. the main news so far is low normal serum magnesium. looks like some regimen juggling is in order! update: high normal ferritin and copper with low normal zinc. see this is why you need data not guesswork. i was ...
by jimmylegs
Mon Oct 28, 2019 5:44 am
Forum: Natural Approach
Topic: UVB for MS Spasticity
Replies: 0
Views: 292

UVB for MS Spasticity

Spasticity is modifiable through phototherapy in patients with relapsing remitting multiple sclerosis: A randomized controlled study (2016) http://www.kamj.eg.net/article.asp?issn=1687-4625;year=2016;volume=22;issue=3;spage=81;epage=90;aulast=Essa Background Multiple sclerosis (MS) is an inflammato...
by jimmylegs
Sun Oct 27, 2019 8:55 am
Forum: Natural Approach
Topic: RCT UVB phototherapy for CIS
Replies: 0
Views: 249

RCT UVB phototherapy for CIS

A randomised, controlled clinical trial of narrowband UVB phototherapy for clinically isolated syndrome: The PhoCIS study (2018) https://journals.sagepub.com/doi/pdf/10.1177/2055217318773112 Abstract Background: The natural history of multiple sclerosis (MS) typically presents with the clinically i...