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by jimmylegs
Tue Oct 27, 2020 12:35 pm
Forum: General Discussion
Topic: MS: Where Will We Be in 2020?
Replies: 0
Views: 46

MS: Where Will We Be in 2020?

ha i don't think i'd seen this one before Multiple Sclerosis: Where Will We Be in 2020? (2011) fft https://onlinelibrary.wiley.com/doi/full/10.1002/msj.20242 The past decade has seen a surge of research interest in multiple sclerosis and an accelerated expansion of investigative efforts into multipl...
by jimmylegs
Thu Oct 22, 2020 11:22 am
Forum: General Discussion
Topic: science 'by TiMS' ;)
Replies: 6
Views: 1389

Re: science 'by TiMS' ;)

Chapter 5 Work package 2a: practices and platforms for sharing experiences of multiple sclerosis patient experience online – interviews, participant observation and content analysis fft https://www.ncbi.nlm.nih.gov/books/NBK401194/ "... Conclusions: online PEx is an integral part of the MS health i...
by jimmylegs
Wed Oct 21, 2020 4:59 am
Forum: Natural Approach
Topic: all things vitamin E
Replies: 19
Views: 14382

Synthetic vitE & myelin genes

i'm haven't done a deep dive to get a better understanding of the potential implications but for now, found this: Synthetic α-Tocopherol, Compared with Natural α-Tocopherol, Downregulates Myelin Genes in Cerebella of Adolescent Ttpa-null Mice https://academic.oup.com/jn/article-abstract/150/5/1031/5...
by jimmylegs
Sat Oct 17, 2020 8:22 am
Forum: General Discussion
Topic: Was a Vaccine at the Origin of my MS?
Replies: 1
Views: 207

Re: Was a Vaccine at the Origin of my MS?

i can't read all the above today. personal short answer, anecdotally maybe it was a factor. statistically, nope. long answer (from my perspective): yes i had a travel vaccine in the weeks preceding my dx. yes my immune system was literally starved and i would say very vulnerable the time. could the ...
by jimmylegs
Tue Oct 13, 2020 2:24 pm
Forum: Natural Approach
Topic: all things vitamin E
Replies: 19
Views: 14382

Re: all things vitamin E

Severe but reversible neuropathy and encephalopathy due to vitamin E deficiency (2017) https://ora.ox.ac.uk/objects/uuid:1213eb7e-65cb-428c-82f9-a8df5603550e "...Severe subacute adult-onset rapidly disabling neuropathy due to vitamin E deficiency is not to our knowledge reported. " i feel like if i...
by jimmylegs
Tue Oct 13, 2020 4:21 am
Forum: Natural Approach
Topic: all things vitamin E
Replies: 19
Views: 14382

Re: all things vitamin E

reminds me of figure one in this article i had found the other day, but haven't looked at too closely yet: Natural forms of vitamin E: metabolism, antioxidant and anti-inflammatory activities and the role in disease prevention and therapy (2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120831/ ...
by jimmylegs
Sun Oct 11, 2020 4:11 pm
Forum: Natural Approach
Topic: all things vitamin E
Replies: 19
Views: 14382

Re: all things vitamin E

ah ha Many tocopherols, one vitamin E (2018) https://www.sciencedirect.com/science/article/abs/pii/S0098299717300419 "Four tocopherols are available in nature and are absorbed with the diet, but only one RRR-α-tocopherol satisfies the criteria of being a vitamin. ... The calculation of the Daily Ref...
by jimmylegs
Sun Oct 11, 2020 10:25 am
Forum: Natural Approach
Topic: all things vitamin E
Replies: 19
Views: 14382

Re: all things vitamin E

this 2012 article confused me for a while...! Vitamin E in ataxia and neurodegenerative diseases: A review (2012) https://www.scirp.org/pdf/wjns20120400006_46258016.pdf ":2. PHYSIOLOGY Vitamin E is an essential fat-soluble Vitamin. Recently, the National Academy of Sciences defined Vitamin E as the ...
by jimmylegs
Mon Oct 05, 2020 2:34 pm
Forum: Natural Approach
Topic: all things vitamin E
Replies: 19
Views: 14382

Re: all things vitamin E

gonna take a closer look at this one, too Gamma-Tocopherol – An Underestimated Vitamin? (2004) https://www.researchgate.net/profile/Ibrahim_Elmadfa/publication/8452393_Gamma-Tocopherol_-_An_Underestimated_Vitamin/links/5aafda52458515ecebea0d23/Gamma-Tocopherol-An-Underestimated-Vitamin.pdf i am inte...
by jimmylegs
Mon Oct 05, 2020 10:50 am
Forum: General Discussion
Topic: No one knows what's wrong with me.
Replies: 75
Views: 2717

Re: No one knows what's wrong with me.

Recent Advances in the Understanding of Vestibular Migraine (2016) https://www.hindawi.com/journals/bn/2016/1801845/ lots of info there, and one paragraph on Nonpharmacological treatment options for VM notes: "...One retrospective study showed that 14% of 38 patients enrolled reported improvement i...
by jimmylegs
Mon Oct 05, 2020 10:21 am
Forum: General Discussion
Topic: No one knows what's wrong with me.
Replies: 75
Views: 2717

Re: No one knows what's wrong with me.

aha results are in! okay that converts to 0.98 mmol/l which is not above normal per se (although it may be from your local lab's perspective), but is definitely in the upper part of the normal range, and therefore less likely to be associated with deficiency symptoms even though the level is normal....
by jimmylegs
Mon Oct 05, 2020 8:05 am
Forum: Natural Approach
Topic: all things vitamin E
Replies: 19
Views: 14382

Re: all things vitamin E

revisiting INO and vit E Acquired Binocular Horizontal Diplopia (1999) https://www.mayoclinicproceedings.org/article/S0025-6196(11)64815-5/fulltext "... INO, the One-and-a-Half Syndrome, and Vitamin E Deficiency.—Clinically, INO is characterized by adduction weakness on the side of a lesion of the m...
by jimmylegs
Mon Oct 05, 2020 4:50 am
Forum: Regimens
Topic: bloodwork monitoring
Replies: 15
Views: 3435

Re: bloodwork monitoring

great to hear from you j, hope u are well all things considered.
i am not quite out of the woods yet over here. what a year!
it has been very nice to be able to help a family friend noticeably, while i puzzle out my own dtls :D
by jimmylegs
Fri Oct 02, 2020 7:58 am
Forum: General Discussion
Topic: No one knows what's wrong with me.
Replies: 75
Views: 2717

Re: No one knows what's wrong with me.

yeah, that was a long one lol :S nice bit of news re your appointment, for sure.

i look forward to seeing your magnesium result, if you can share when it comes through :)
by jimmylegs
Fri Oct 02, 2020 6:37 am
Forum: General Discussion
Topic: No one knows what's wrong with me.
Replies: 75
Views: 2717

Re: No one knows what's wrong with me.

hi again :) more progress! a couple of thoughts: She also kept saying everything wrong with me was to do with my alcohol consumption. it would be great to have some evidence of alcohol-induced nutrient depletion if applicable in your case, so that at very least in the best case scenario you could ru...

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