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That's interesting - my dad's hands go numb though he has never received a specific diagnosis for it. I don't have it though my neuro did comment that my fingers were slightly purple. They've always been that colour so I didn't think much of it.

Cyclops

That's a very interesting piece of news. Nice one

I've been sleeping with the bed inclined for about a month. I feel far more rested when I wake in the mornings. After a couple of weeks I started having sort of flashbacks - remembering things I hadn't thought about in years. It was quite intense for a few days. It was only afterwards that I thought...

#1 and #2 for me. I remember as a child doing handstands and my face would be bright red and everyone else would be fine. I get that bubble thing in my neck - it just lasts a second, a bit like a muscle spasm. Not sure what the bubble feeling might actually be - I doubt very much it's actually bubbl...

Jamie,

Great news that Mel is doing so well - long may it continue.

You mentioned Dr D is off to Liverpool - any idea who he's off to see? It would be great if we had some British docs on board.

Cyclops

I was diagnosed with MS whilst abroad (expensive). When I got back to the UK the NHS paid for all my treatment abroad without question. I spent 15 mins with a UK neuro to confirm diagnosis and was then offered either interferon or copaxone. I chose copaxone and the first batch was delivered to my ho...

That's right. All meds are free now but there was no charge for MS drugs anyway as they are for long term conditions. It will be interesting to see what happens if L is able to get the treatment here. Normally the NHS will only pay for approved treatments and the drawback there is they are not too q...

Sicko is out-of-date. The £6.65 charge for medice has been scrapped in Scotland and I think its its in the process of being scrapped in England too!

That's excellent news. Hopefully you will be the first of many to get the procedure.

Cyclops

From the ECTRIMS website: Cyclops A Phase I/II dose-escalation trial of oral vitamin D3 with calcium supplementation in patients with multiple sclerosis J. M. Burton1; S. Kimball2; R. Vieth2; A. Bar-Or3; H. Dosch4; L. Thibault5; S. Kilborn5; C. D'Souza6; R. Cheung4; M. Ursell7; P. O'Connor1 1. St. M...

I found this on the ECTRIMS website. Not sure if it has already been posted: Cyclops Clinical effect of the neuroprotectant MN-166 in relapsing multiple sclerosis: year 2 data R. Gammans1; F. Barkhof2; J. Drulovic3 1. Development, MediciNova, San Diego, CA, USA. 2. VUMC, Amsterdam, Netherlands. 3. I...

...and this one: Immunoablation with high-dose cyclophosphamide for refractory multiple sclerosis S. Tilwalli1; R. Balabanov1; D. Stefoski1; G. Katsamakis1; M. Ko1; J. Shammo1; S. Gregory1 1. Neurology, Rush University Medical Center, Chicago, IL, USA. High-dose cyclophosphamide (HD-CTX) has demonst...

I found this on the ECTRIMS website: An open-label study of high dose cyclophosphamide for moderate to severe refractory multiple sclerosis D. Callegaro1; S. L. Apóstolos-Pereira1; M. Scaff1; P. E. Marchiori1 1. Clinics Hospital, São Paulo, Brazil. Treatment-refractory clinically active multiple scl...

Maybe that's not such bad news. If the company finally closes maybe it will pave the way for someone else to take over the technology.

As a (sort of) scientist myself, I know that a failed experiement can be just as informative as a successful one.

Cyclops

Does anyone have details about the phase III trials? Specifically, will the protocol contain a placebo arm?

Cyclops