Search found 287 matches

by finn
Mon Aug 17, 2009 7:51 am
Forum: General Discussion
Topic: Inflammation vs. neurodegeneration
Replies: 313
Views: 63872

Lyon wrote:...and Finn from the grave!
"The rumors of my death have been greatly exaggerated".

It's great that dignan's posts have kept this thread alive. Now at least it's clear that Prineas et al are questioning both autoimmunity and Lucchinetti's theory. Interesting.

-finn
by finn
Mon May 12, 2008 8:00 am
Forum: General Discussion
Topic: Inflammation vs. neurodegeneration
Replies: 313
Views: 63872

dignan, thanks for sharing the abstract with the rest of us. I found its subject very interesting. By coincidence, a dear friend of mine sent me the full article of the same study few days ago, and thus gave me a good reason to visit this thread again. I think this abstract sounds interesting, altho...
by finn
Sat Jan 05, 2008 1:32 am
Forum: General Discussion
Topic: Inflammation vs. neurodegeneration
Replies: 313
Views: 63872

Sharon, thank you for making my day :-)

It is really great to see this old thread getting bumped up again, and I appreciate your feedback very much.

Thanks for sharing Dr Cohen's presentation, too. It was good.

Be well.

-finn
by finn
Mon Dec 24, 2007 4:54 am
Forum: General Discussion
Topic: May I just say …
Replies: 12
Views: 2787

Merry Christmas everybody!

-finn

btw, as you all probably know, original Father Christmasses come from Finland:
Rare Exports I, Rare Exports II
by finn
Tue Oct 23, 2007 5:22 am
Forum: General Discussion
Topic: ECTRIMS 2007 Notes
Replies: 9
Views: 2739

Thank you and Hollie for great report, Art. I hope you don't mind that parts of it will be soon translated and posted on a Finnish MS board.

-finn
by finn
Fri Sep 28, 2007 11:38 pm
Forum: General Discussion
Topic: Sad news
Replies: 78
Views: 15109

I'm so sorry for your loss, Harry.

-finn
by finn
Sun Sep 16, 2007 8:18 am
Forum: General Discussion
Topic: Position re minocycline trials
Replies: 11
Views: 3167

This is good news! Thanks for sharing it, Ian. Actually, it gives me an excuse to show this impressive graph illustrating the lack of relapses in the previous Canadian minocycline trial (a triangle means a relapse). During the last 18 months none of the patients had any relapses: http://img181.image...
by finn
Sat Aug 18, 2007 7:59 am
Forum: General Discussion
Topic: How Chronic Stress Worsens Neurodegenerative Disease Course
Replies: 8
Views: 2751

Dom, like the study behind Frank's link shows, it is stressful for both mice and men to face an unknown and aggressive male. But what comes to interferon-gamma, there might be a difference between the two species. Back in the 80s researchers were able to cure EAE mice with interferon-gamma, but in h...
by finn
Sat Aug 04, 2007 11:10 pm
Forum: Drug Pipeline
Topic: Revimmune
Replies: 43
Views: 11445

Bob,
Lyon wrote:...if...might...
Boy, it was a long post. Have you concidered running for politics?

Btw, maybe instead of "plasticity" it might be better to use the term "regenerative potential" more often in your hypothesis. Or did I get it wrong?

-finn
by finn
Sat Aug 04, 2007 7:54 am
Forum: Drug Pipeline
Topic: Revimmune
Replies: 43
Views: 11445

Bob, I like to think that I would agree with bromley and Raven in that the risk of ITP and Grave's disease are acceptable risks when compared to the other treatments currently offered. Yes. It is wise to compare possible risks vs. benefits of a drug treatment. Like Dr. Agnell said in an interview: ...
by finn
Fri Aug 03, 2007 3:47 am
Forum: Drug Pipeline
Topic: Revimmune
Replies: 43
Views: 11445

Bob, That's one of the reasons I'm cautiously optomistic about Campath. Something which is supposed to be alleviating the total immune system should alleviate all the autoimmune diseases and NEVER increase the risk of another autoimmune disease. In case you didn't know, in 2005 the Campath trial wa...
by finn
Fri Aug 03, 2007 3:44 am
Forum: General Discussion
Topic: MS risk genes identified
Replies: 31
Views: 6406

Frank wrote:Did they maybe just go after genes that would fit the autoimmune hypothesis.
Good question, Frank. IMO, the study setting seems to have been biased towards autoimmune theory. In any case, I personally don't think this study will make that much difference.

-finn
by finn
Fri Jul 27, 2007 4:35 am
Forum: Drug Pipeline
Topic: Research news
Replies: 6
Views: 2831

Ian, thanks!

Bob, I agree.

-finn
by finn
Tue Jul 24, 2007 11:09 pm
Forum: General Discussion
Topic: Inflammation vs. neurodegeneration
Replies: 313
Views: 63872

Bob,

Since I got you confused, I must have used the phrase the wrong way. What I meant was that
  • when there is inflammation, there is also neurodegeneration.
  • there can be neurodegeneration without inflammation.
I hope this clarifies the way I see it.

-finn
by finn
Tue Jul 24, 2007 11:06 pm
Forum: General Discussion
Topic: Reaching the "tipping point"
Replies: 12
Views: 2973

Dom,

I'm glad I could be of help. I always enjoy reading your posts, but to tell you the truth, the line spacing was a bit disturbing.

-finn