Search found 1747 matches
- Wed Mar 06, 2024 7:35 am
- Forum: General Discussion
- Topic: An interesting paper about EBV and MS
- Replies: 0
- Views: 728
An interesting paper about EBV and MS
Ineffective control of Epstein–Barr virus infection is seen in MS https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10883233/ The cause of multiple sclerosis (MS) is not known. Incidence and prevalence rates differ in the various regions of the world. Migration studies have shown that age at migration h...
- Wed Mar 06, 2024 7:30 am
- Forum: MS Etiology and Pathogenesis
- Topic: Plasmapheresis and Immunoadsorption: How it works
- Replies: 0
- Views: 1091
Plasmapheresis and Immunoadsorption: How it works
Miniaturized Adsorbers in Exploring the Cellular and Molecular Effects of Blood Purification https://www.mdpi.com/1422-0067/25/5/2590 Abstract Immunoadsorption (IA) has proven to be clinically effective in the treatment of steroid-refractory multiple sclerosis (MS) relapses, but its mechanism of ac...
- Tue Mar 05, 2024 12:41 pm
- Forum: MS Etiology and Pathogenesis
- Topic: Ineffective control of Epstein–Barr virus infection is seen in MS
- Replies: 1
- Views: 370
Ineffective control of Epstein–Barr virus infection is seen in MS
Ineffective control of Epstein–Barr virus infection is seen in MS https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10883233/ The cause of multiple sclerosis (MS) is not known. Incidence and prevalence rates differ in the various regions of the world. Migration studies have shown that age at migration h...
- Tue Mar 05, 2024 1:26 am
- Forum: MS Etiology and Pathogenesis
- Topic: 14 urine metabolites associated with PMS
- Replies: 0
- Views: 532
14 urine metabolites associated with PMS
Potential Metabolite Biomarkers of Multiple Sclerosis from Multiple Biofluids https://pubs.acs.org/doi/abs/10.1021/acschemneuro.3c00678# Abstract Multiple sclerosis (MS) is a chronic and progressive neurological disorder without a cure, but early intervention can slow disease progression and improv...
- Thu Feb 01, 2024 4:57 am
- Forum: MS Etiology and Pathogenesis
- Topic: Soluble factors in CSF
- Replies: 1
- Views: 1327
Again "soluble factors"
White matter paramagnetic rim and non-rim lesions share a periventricular gradient in multiple sclerosis https://journals.sagepub.com/doi/abs/10.1177/13524585231224681 Background : Paramagnetic rim white matter (WM) lesions (PRL) are thought to be a main driver of non-relapsing multiple sclerosis (M...
- Thu Feb 01, 2024 4:55 am
- Forum: MS Etiology and Pathogenesis
- Topic: Ibudilast reduces smouldering lesions
- Replies: 0
- Views: 847
Ibudilast reduces smouldering lesions
Slowly enlarging lesions (SEL) or "smouldering" lesions are thought to be the physiological substract of MS progression. Ibudilast reduces slowly enlarging lesions in progressive multiple sclerosis https://journals.sagepub.com/doi/abs/10.1177/13524585231224702 Background : Ibudilast has sh...
- Wed Jan 17, 2024 10:36 am
- Forum: MS Etiology and Pathogenesis
- Topic: Antivirals in MS: Tenofovir
- Replies: 4
- Views: 3142
The Answer Lies in the Details
In the Era of Antiviral Trials for MS, the Answer Lies in the Details https://www.msard-journal.com/article/S2211-0348(24)00023-3/fulltext Abstract After a seminal epidemiological study linked infection with the Epstein-Barr virus (EBV) to multiple sclerosis (MS), there is a consensus that EBV is t...
- Wed Jan 17, 2024 10:34 am
- Forum: MS Etiology and Pathogenesis
- Topic: Antivirals in MS: Tenofovir
- Replies: 4
- Views: 3142
second report
Radiologic and clinical stability in an HIV-negative MS patient after tenofovir: an updated case report https://www.sciencedirect.com/science/article/abs/pii/S2211034823008957 Introduction In 2018, members of our team published an interesting case of a patient with newly diagnosed aggressive relaps...
- Wed Jan 17, 2024 10:32 am
- Forum: MS Etiology and Pathogenesis
- Topic: Antivirals in MS: Tenofovir
- Replies: 4
- Views: 3142
Antivirals in MS: Tenofovir
Long-term MRI and clinical stability in an HIV-positive patient with multiple sclerosis on tenofovir: a case report https://www.sciencedirect.com/science/article/abs/pii/S2211034823008969 Introduction The Epstein-Barr virus (EBV) is the likely leading cause of multiple sclerosis (MS). (Bjornevik et...
- Sun Jan 14, 2024 11:51 pm
- Forum: Chronic Cerebrospinal Venous Insufficiency (CCSVI)
- Topic: obstruction of the glymphatic system
- Replies: 2
- Views: 1576
obstruction of the glymphatic system
The dilated veins surrounding the cord in multiple sclerosis suggest elevated pressure and obstruction of the glymphatic system https://www.sciencedirect.com/science/article/pii/S1053811924000120 Highlights • There is dilatation of the bridging veins traversing the subarachnoid space surrounding bot...
- Tue Jan 09, 2024 11:48 am
- Forum: MS Etiology and Pathogenesis
- Topic: Microglia in MS. Review
- Replies: 1
- Views: 1752
- Tue Nov 21, 2023 3:42 am
- Forum: MS Etiology and Pathogenesis
- Topic: T1-dark-rim as a sign for smouldering inflammation
- Replies: 2
- Views: 3137
MRI as a biomarker of the smouldering component of multiple sclerosis: time to wake up
MRI as a biomarker of the smouldering component of multiple sclerosis: time to wake up
This comment refers to the article available at https://doi.org/10.1007/s00330-023-10173-6.
This comment refers to the article available at https://doi.org/10.1007/s00330-023-10173-6.
- Tue Nov 21, 2023 3:41 am
- Forum: MS Etiology and Pathogenesis
- Topic: T1-dark-rim as a sign for smouldering inflammation
- Replies: 2
- Views: 3137
Magnetization transfer and diffusion tensor imaging
Longitudinal analysis of new multiple sclerosis lesions with magnetization transfer and diffusion tensor imaging https://link.springer.com/article/10.1007/s00330-023-10173-6 Abstract Objective The potential of magnetization transfer imaging (MTI) and diffusion tensor imaging (DTI) for the detection ...
- Tue Nov 21, 2023 3:38 am
- Forum: MS Etiology and Pathogenesis
- Topic: T1-dark-rim as a sign for smouldering inflammation
- Replies: 2
- Views: 3137
T1-dark-rim as a sign for smouldering inflammation
The T1-dark-rim: A novel imaging sign for detecting smoldering inflammation in multiple sclerosis https://www.researchsquare.com/article/rs-3582841/v1 Abstract Objectives : Paramagnetic rim lesions (PRLs), usually identified in susceptibility-weighted imaging (SWI), are a promising prognostic bioma...
- Sun Nov 19, 2023 8:02 am
- Forum: MS Etiology and Pathogenesis
- Topic: Seroreactivity 10 years befores MS onset
- Replies: 0
- Views: 2328
Seroreactivity 10 years befores MS onset
Seroreactivity against lytic, latent and possible cross-reactive EBV antigens appears on average 10 years before MS induced preclinical neuroaxonal damage https://jnnp.bmj.com/content/early/2023/10/06/jnnp-2023-331868.abstract Abstract Background Multiple sclerosis (MS) and presymptomatic axonal inj...