Search found 985 matches

by Leonard
Thu Apr 04, 2019 11:41 pm
Forum: General Discussion
Topic: A new concept for MS and other autoimmune diseases
Replies: 890
Views: 197168

Re: A new concept for MS and other autoimmune diseases

Autoimmunity and our society Our cells have very small deviations, called Single Nucleotide Polymorphisms (SNPs) which have always been considered to be irrelevant. But they are not, they are very important as they are gatekeepers that signal whether a cell is virally infected by a herpes virus. SNP...
by Leonard
Thu Apr 04, 2019 11:36 pm
Forum: General Discussion
Topic: A new concept for MS and other autoimmune diseases
Replies: 890
Views: 197168

Re: A new concept for MS and other autoimmune diseases

Elliot, Vesta, thank you. I agree with you that we must take care of ourselves. That is what I try to do as well. But besides what we do in our own private sphere, public intervention and funding would seem logical because there is not a patentable molecule involved here, the underlying thinking (se...
by Leonard
Sun Feb 10, 2019 5:54 am
Forum: General Discussion
Topic: A new concept for MS and other autoimmune diseases
Replies: 890
Views: 197168

Re: A new concept and treatment options for MS

On the Internet we find a mountain of medical publications, often in the open literature. Most of these publications consider the problem "in their own domain" resulting in an incomplete picture. But if we bring it all together, we can see a huge breakthrough on the horizon built on a series of inte...
by Leonard
Sun Feb 10, 2019 5:42 am
Forum: General Discussion
Topic: A new concept for MS and other autoimmune diseases
Replies: 890
Views: 197168

Re: A new concept and treatment options for MS

We have seen that the oxidative stress cycle originates from a herpes viral infection. As the following article suggests, it may now well be that herpes viral spreading is facilitated by oxidative stress. That is bad because it would be a further stimulous for the vicious cycle, a sort of self-perpe...
by Leonard
Fri Feb 08, 2019 5:39 am
Forum: General Discussion
Topic: A new concept for MS and other autoimmune diseases
Replies: 890
Views: 197168

Re: A new concept and treatment options for MS

https://www.ncbi.nlm.nih.gov/pubmed/29457866 on Epigenetic effects of metformin: From molecular mechanisms to clinical implications If we assume for a moment that all autoimmune diseases originate from the same underlying mechanism (i.e. B cells that cross react with viral epitopes after epigenetic ...
by Leonard
Mon Feb 04, 2019 5:57 am
Forum: General Discussion
Topic: A new concept for MS and other autoimmune diseases
Replies: 890
Views: 197168

Re: A new concept and treatment options for MS

From the other thread on MTA and MS https://www.thisisms.com/forum/viewtopic.php?f=1&t=3628 and in particular https://www.thisisms.com/forum/viewtopic.php?f=1&t=3628#p256597 If the methylation cycle is restored (normally should be done by restoring the gut function but here is it is done by oral adm...
by Leonard
Mon Feb 04, 2019 5:50 am
Forum: General Discussion
Topic: MTA and MS
Replies: 5
Views: 1878

Re: MTA and MS

If the methylation cycle is restored (normally should be done by restoring the gut function but here is it is done by oral administration), cellular expression will be down and the autoimmune reaction will come to a halt. I don't exclude the possibility that some remyelination may occur at that poin...
by Leonard
Sun Feb 03, 2019 1:04 am
Forum: General Discussion
Topic: A new concept for MS and other autoimmune diseases
Replies: 890
Views: 197168

Re: A new concept and treatment options for MS

http://www.neurology.org/content/61/10/1373/F2.large.jpg? http://www.neurology.org/content/61/10/1373/F2.expansion.html Note the overall trend in the figure! ---- The virus infection and spreading was there all the time. Normally the virus is latent and the immune system is tolerant. The microbiome...
by Leonard
Sun Feb 03, 2019 12:59 am
Forum: General Discussion
Topic: Atorvastatin
Replies: 12
Views: 350

Re: Atorvastatin

Leo: Virus - maybe, but the problem would already be found, I guess ------------------------------------------------------------------ What changes over time with MS? I do not know. no one knows exactly today. Just theories, stencils .. but the virus does not fit me. But sure, everything is possibl...
by Leonard
Sat Feb 02, 2019 12:10 am
Forum: General Discussion
Topic: Atorvastatin
Replies: 12
Views: 350

Re: Atorvastatin

Petr,

of course statins have an effect on progression.

see also viewtopic.php?f=1&t=15188&p=256582#p256581

Leo
by Leonard
Sat Feb 02, 2019 12:03 am
Forum: General Discussion
Topic: A new concept for MS and other autoimmune diseases
Replies: 890
Views: 197168

Re: A new concept and treatment options for MS

We have seen what autoimmune diseases are, and we understand the specific case of MS. We have also seen that the power of the system prevents change. Our main question is now: how do we get change? What can we contribute? How do we help to initiate change? Please share any views you may have with me.
by Leonard
Sat Feb 02, 2019 12:00 am
Forum: General Discussion
Topic: A new concept for MS and other autoimmune diseases
Replies: 890
Views: 197168

Re: A new concept and treatment options for MS

https://www.thisisms.com/forum/viewtopic.php?f=1&t=30717 on Atorvastatin For sure, statins have an effect on the fat metabolism. See also step 7 of https://www.thisisms.com/forum/general-discussion-f1/topic15188-825.html#p251748 I remember an earlier study on the effect of statins that was reported ...
by Leonard
Wed Jan 30, 2019 1:26 am
Forum: General Discussion
Topic: A new concept for MS and other autoimmune diseases
Replies: 890
Views: 197168

Re: A new concept and treatment options for MS

I guess this depends on who you ask... This already shows the first problem i.e. that it is not clear how to define "the experts" or who is an expert... I know experts who know for sure that herpes causes MS. Google may help you find some of these experts. You may also find some names further back i...
by Leonard
Tue Jan 29, 2019 6:12 am
Forum: General Discussion
Topic: A new concept for MS and other autoimmune diseases
Replies: 890
Views: 197168

The Power of the System

The Power of the System We know now what causes autoimmune diseases. We know to a certain level of detail what is MS and what causes it. Now that the technicalities of the diseases are known, we can work towards more effective therapies. But this requires change, change of the system. Furthermore, t...
by Leonard
Mon Jan 21, 2019 12:59 am
Forum: General Discussion
Topic: Prevalence of asthma in multiple sclerosis
Replies: 2
Views: 172

Re: Prevalence of asthma in multiple sclerosis

Hi Petr,

See viewtopic.php?f=1&t=15188&p=256485#p256485 for an explanation of the comorbidity.

best, Leo