Search found 1002 matches

by Leonard
Fri Oct 18, 2019 2:17 am
Forum: General Discussion
Topic: A new concept for MS and other autoimmune diseases
Replies: 897
Views: 203871

Re: A new concept for MS and other autoimmune diseases

Copied from the other thread on genetic and environmental risk factors on https://www.thisisms.com/forum/viewtopic.php?f=1&t=31202 In my case, the left Internal Jugular Vein (IJV) is dominant. Which is strange. Normally they should be equal. So why is that? Because the right IJV was blocked, a birth...
by Leonard
Fri Oct 18, 2019 1:45 am
Forum: General Discussion
Topic: Environmental and genetic risk factors
Replies: 4
Views: 99

Re: Environmental and genetic risk factors

.. cards were dealt before birth, still later it was just a bad game.. Correct. In my case, the left Internal Jugular Vein (IJV) is dominant. Which is strange. Normally they should be equal. So why is that? Because the right IJV was blocked, a birth defect. During the foetal phase, the left IJV gre...
by Leonard
Sun Oct 13, 2019 10:36 pm
Forum: General Discussion
Topic: Environmental and genetic risk factors
Replies: 4
Views: 99

Re: Environmental and genetic risk factors

This nitty gritty stuff only adds to the confusion. We should begin at a higher abstraction level.
by Leonard
Sat Sep 28, 2019 12:27 am
Forum: General Discussion
Topic: A new concept for MS and other autoimmune diseases
Replies: 897
Views: 203871

Re: A new concept for MS and other autoimmune diseases

From the other thread on Why Don't We Have a Vaccine Against Autoimmune Diseases? 2019 Roseman University College of Medicine, Las Vegas Why Don't We Have a Vaccine Against Autoimmune Diseases? - A Review. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640150/ Abstract This review examines some of th...
by Leonard
Sat Sep 28, 2019 12:12 am
Forum: General Discussion
Topic: Why Don't We Have a Vaccine Against Autoimmune Diseases?
Replies: 1
Views: 101

Re: Why Don't We Have a Vaccine Against Autoimmune Diseases?

https://pdfs.semanticscholar.org/0e4f/fc1ed59fb399399547b68488b9f90be44f6f.pdf Vaccination and Autoimmunity—‘Vaccinosis’: A Dangerous Liaison? quote The question of a connection between vaccination and autoimmune illness (or phenomena) is surrounded by controversy. A heated debate is going on regard...
by Leonard
Mon Sep 23, 2019 1:03 am
Forum: General Discussion
Topic: A new concept for MS and other autoimmune diseases
Replies: 897
Views: 203871

Re: A new concept for MS and other autoimmune diseases

Besides the medical technical aspects, we have encountered here many times the systemic aspects of the problem. As regards the latter, we may feel encouraged by this article where we learn that ever more prominent doctors speak out against the medical establishment and that it is starting to look li...
by Leonard
Mon Sep 23, 2019 12:10 am
Forum: General Discussion
Topic: A new concept for MS and other autoimmune diseases
Replies: 897
Views: 203871

Re: A new concept for MS and other autoimmune diseases

2019 Jul 16 Department of Pathology, Division of Microbiology and Immunology, University of Utah School of Medicine, Salt Lake City The microbiota protects from viral-induced neurologic damage through microglia-intrinsic TLR signaling https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6634972/ Abstract S...
by Leonard
Mon Sep 23, 2019 12:06 am
Forum: General Discussion
Topic: Focus on the gut-brain axis
Replies: 42
Views: 3389

Re: Focus on the gut-brain axis

2019 Jul 16 Department of Pathology, Division of Microbiology and Immunology, University of Utah School of Medicine, Salt Lake City The microbiota protects from viral-induced neurologic damage through microglia-intrinsic TLR signaling https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6634972/ Abstract S...
by Leonard
Sun Sep 01, 2019 11:20 pm
Forum: General Discussion
Topic: A new concept for MS and other autoimmune diseases
Replies: 897
Views: 203871

Re: A new concept for MS and other autoimmune diseases

The mystery of autoimmune diseases revealed Taking control of autoimmunity: a scourge of our modern age Autoimmune diseases—such as multiple sclerosis (MS), lupus, Crohn’s disease, type 1 diabetes, and rheumatoid arthritis—cause the body to destroy itself. Recent studies suggest that the mechanisms...
by Leonard
Tue May 28, 2019 8:58 am
Forum: General Discussion
Topic: A new concept for MS and other autoimmune diseases
Replies: 897
Views: 203871

We need a paradigm change

The medical sector does not know what is or what causes MS. But it's even worse than that. In fact, they don't know what is autoimmunity, what causes autoimmune diseases. But I am sure some day the health paradigm will change. If we look back at the old (= our current) health paradigm in say 2030, w...
by Leonard
Tue May 28, 2019 8:53 am
Forum: General Discussion
Topic: A new concept for MS and other autoimmune diseases
Replies: 897
Views: 203871

Re: A new concept for MS and other autoimmune diseases

The iNOS Activity During an Immune Response Controls the CNS Pathology in Experimental Autoimmune Encephalomyelitis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458273/ from https://www.thisisms.com/forum/viewtopic.php?f=1&t=30982 My view: iNOS is the result of a physiological trauma induced by T c...
by Leonard
Tue May 28, 2019 8:26 am
Forum: General Discussion
Topic: MS is a Clinically Defined Disease
Replies: 2
Views: 300

Re: MS is a Clinically Defined Disease

Vesta, You are right: the medical sector does not know what is or what causes MS. But it is a lot worse than that. In fact, they ain’t got a clue what is autoimmunity, what causes autoimmune diseases. If, at some point in the future we look back at 2019, we will look at it in a way that people looke...
by Leonard
Sun May 26, 2019 7:25 am
Forum: General Discussion
Topic: iNOS
Replies: 1
Views: 143

Re: iNOS

Thank you Petr

iNOS is the result of a physiological trauma induced by T cells (inflammation).
Highly localised oxidative stress results from EBV B cell cross reaction (progression).

The full story is here: viewtopic.php?f=1&t=15188&start=885#p257234
by Leonard
Wed May 22, 2019 1:09 am
Forum: General Discussion
Topic: Epstein-Barr Virus and miRNAs
Replies: 2
Views: 249

Re: Epstein-Barr Virus and miRNAs

Thank you Petr for this link. The herpes virus causes MS, EBV is a herpes strain. The recognition of the virus at cellular level is done by SNPs. And likely via SNPs the miRNA is involved in B cell transformation. The SNPs function within the miRNA and within miRNA targets. As such, SNPs modulate mi...
by Leonard
Wed May 08, 2019 4:05 am
Forum: General Discussion
Topic: Different minerals
Replies: 2
Views: 148

Re: Different minerals

A short of minerals could derail anti-oxidant working, but then only in the progressive phase. And one would need to be clearly deficient as well to see an effect. The oxidative stress cycle only starts gradually after the inflammatory cycle(s). But here they look more to the onset and thus inflamma...