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Yes, for 2 years now. It's great for me. Within 2 days, it took away painful spasticity I had in my right leg for over a year. Improves fatigue, but not balance.

MS HISTORY Male/Female: F Age: 37 Date & type of neurological diagnosis: SPMS and I may have had it since pre-teen. Don't recall ever having a relapse. Diagnosed Feb 2008. Lesion locations, number: Many, spine and brain, both sides. MS treatments: Never took DMDs. Take 4-AP, wheat-free/dairy-fre...

I'm so much worse in the mornings, that is the only time I have to use a cane. Every day. My stenosis is in my left jugular only.

I'm in Canada, have PPMS, and I've been on 4-AP for 9 months. I walk to work, the same route every day, so I'm able to notice differences immediately. The first day I took 4-AP, I had a splitting headache. The second day I took it, I was racing to make lights, rather than looking for a chance to sto...