Search found 710 matches: vascular

Searched query: +vascular

by Leonard
Sun Sep 01, 2019 11:20 pm
Forum: General Discussion
Topic: A new concept for MS and other autoimmune diseases
Replies: 893
Views: 202129

Re: A new concept for MS and other autoimmune diseases

... body the oxidative stress develops as a result of prior viral anchoring. Multiple sclerosis is a special case in the sense that, more than SNPs, vascular narrowings compromise the blood brain barrier and allow the viral loading, but the unfolding is the same. Parkinson’s is believed to be caused ...
by vesta
Sun Sep 01, 2019 12:21 am
Forum: General Discussion
Topic: I need a REAL MS Specialist
Replies: 5
Views: 256

Re: I need a REAL MS Specialist

... which has made alternatives available. As pwMS take charge of their health care, they are doing MUCH better. See Joan Beal’s latest post on the Vascular Connection. Dr Zamboni’s publication of his CCSVI theory Dec 2008 opened the door to enormous research on blood/fluid circulation in MS and ...
by vesta
Sun Aug 25, 2019 12:44 am
Forum: General Discussion
Topic: I need a REAL MS Specialist
Replies: 5
Views: 256

I need a REAL MS Specialist

... and when I rose to leave the old handicapping rigidity had returned. Did this recovery really happen ? And why ? I read recently on Dr Zamboni’s Vascular Connection Facebook page of a woman who woke after Venoplasty to find she no longer suffered from « drop-foot ».Renewed blood flow apparently ...
by vesta
Sun Jul 21, 2019 8:30 am
Forum: General Discussion
Topic: Status, not Science, rules MS treatment
Replies: 2
Views: 185

Status, not Science, rules MS treatment

... what MS is nor how to treat it. That doesn’t prevent their throwing DMVs at the hapless patient and being generally obnoxious in dismissing the vascular connection to MS. In my last past I mentioned Dr. Schelling’s history of the Vascular Connection in MS. On page 33 of his paper MULTIPLE SCLEROSIS : ...
by Petr75
Fri Jul 05, 2019 10:43 am
Forum: General Discussion
Topic: Pericytes
Replies: 0
Views: 108

Pericytes

... to myelin damage, during MS, this regenerative phenomenon decays in efficiency or even fails. CNS-resident pericytes (CNS-PCs) are essential for vascular homeostasis regulating blood-brain barrier (BBB) permeability and stability as well as endothelial cells (ECs) function during angiogenesis ...
by Leonard
Tue May 28, 2019 8:58 am
Forum: General Discussion
Topic: A new concept for MS and other autoimmune diseases
Replies: 893
Views: 202129

We need a paradigm change

... on autoimmunity and our society: https://www.thisisms.com/forum/viewtopic.php?f=1&t=15188&start=885#p257234 For most of us, MS is caused by vascular narrowings in the neck (CCSVI) which breaches the blood brain barrier and then allows for the viral entry. For other autoimmune diseases, cells ...
by Leonard
Tue May 28, 2019 8:26 am
Forum: General Discussion
Topic: MS is a Clinically Defined Disease
Replies: 2
Views: 262

Re: MS is a Clinically Defined Disease

... cells. The full picture is here: https://www.thisisms.com/forum/viewtopic.php?f=1&t=15188&start=885#p257234 For most of us, MS is caused by vascular narrowings in the neck (CCSVI) which breaches the blood brain barrier. For other autoimmune diseases, cells may permit viral infection because ...
by Petr75
Tue May 28, 2019 7:34 am
Forum: General Discussion
Topic: PECAM-1
Replies: 0
Views: 74

PECAM-1

... of the pathogenesis of multiple sclerosis (MS). Platelet endothelial cell adhesion molecule-1 (PECAM-1; CD31) is expressed on cells of the vascular compartment and regulates vascular integrity and immune cell trafficking. Involvement of PECAM-1 in MS pathogenesis has been suggested by the ...
by vesta
Tue May 28, 2019 7:01 am
Forum: General Discussion
Topic: MS is a Clinically Defined Disease
Replies: 2
Views: 262

MS is a Clinically Defined Disease

... Steps to MS Health) Emphasis should be placed on the obstruction of cerebro-spinal fluid What is missing in all official MS discussions is the vascular, fluid circulation obstruction issue which ends by damaging the Central Nervous System. When Dr Zamboni proposed the CCSVI theory the MS lobby ...
by Petr75
Sat May 25, 2019 5:17 am
Forum: General Discussion
Topic: Schwann cell
Replies: 0
Views: 95

Schwann cell

... transplantation in the demyelinated spinal cord. The data highlight for the first time that SC migrate preferentially along blood vessels in perivascular extracellular matrix (ECM), avoiding CNS myelin. We demonstrate in vitro and in vivo that this migration route occurs by virtue of a dual mode ...
by Petr75
Thu May 23, 2019 11:30 am
Forum: General Discussion
Topic: Aberrant oligodendroglial-vascular interactions
Replies: 2
Views: 193

Re: Aberrant oligodendroglial-vascular interactions

... Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences , University at Buffalo, State University of New York , Buffalo Vascular aspects of multiple sclerosis: emphasis on perfusion and cardiovascular comorbidities https://www.ncbi.nlm.nih.gov/pubmed/31003583 Abstract ...
by 1eye
Thu May 23, 2019 8:10 am
Forum: General Discussion
Topic: Aberrant oligodendroglial-vascular interactions
Replies: 2
Views: 193

Re: Aberrant oligodendroglial-vascular interactions

Could this be related to why treatment for CCSVI sometimes works for a while?
by Petr75
Sat May 18, 2019 11:38 am
Forum: General Discussion
Topic: Aberrant oligodendroglial-vascular interactions
Replies: 2
Views: 193

Aberrant oligodendroglial-vascular interactions

2019 May Department of Neurology, University of California at San Francisco, San Francisco Aberrant oligodendroglial-vascular interactions disrupt the blood-brain barrier, triggering CNS inflammation https://www.ncbi.nlm.nih.gov/pubmed/30988524 Abstract Disruption of the blood-brain ...
by jimmylegs
Tue May 07, 2019 7:51 am
Forum: General Discussion
Topic: 2007 Review: Reversible Cerebral Vasoconstriction Syndromes
Replies: 0
Views: 110

2007 Review: Reversible Cerebral Vasoconstriction Syndromes

... balanced by 2 opposing groups of observations. On the one hand, successful outcomes, including alleviation of symptoms and rapid reversibility of vascular abnormalities, have been reported with various methods of treatment, including calcium-channel blockers (38, 91); brief courses of glucocorticoids ...
by vesta
Tue May 07, 2019 2:40 am
Forum: General Discussion
Topic: Retinal Tissue Perfusion reduced by 42% in MS !!!
Replies: 4
Views: 287

Re: Retinal Tissue Perfusion reduced by 42% in MS !!!

... oral treatment for relapsing-remitting multiple sclerosis. The S1P-S1P receptor signaling system also plays important roles in maintenance of vascular integrity since it suppresses sprouting angiogenesis and regulates vascular permeability. Dysfunction of the S1P-S1P receptor signaling system ...