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Focus on the gut-brain axis

Last post by Petr75 « Tue Jan 21, 2020 8:25 am
Posted in General Discussion
Replies: 61
by Petr75 » Sun Nov 04, 2018 12:14 pm » in General Discussion
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First post

2018 Oct 7
Department of Clinical Neurosciences, Cumming School of Medicine, University of Calgary, Canada
Focus on the gut-brain axis: Multiple...

Last post

2020 Jan 17
State Key Laboratory of Genetic Engineering and Collaborative Innovation Center for Genetics and Development, School of Life Sciences,...
61 Replies

5384 Views

Last post by Petr75
Tue Jan 21, 2020 8:25 am
Cannabinoid WIN-55,212-2

Last post by Petr75 « Tue Jan 21, 2020 8:05 am
Posted in Medical Marijuana

by Petr75 » Tue Jan 21, 2020 8:05 am » in Medical Marijuana

2020 Jan 17
Department of Psychiatry and Psychotherapy, University of Göttingen and Center Nanoscale Microscopy and Molecular Physiology of the Brain...

0 Replies

9 Views

Last post by Petr75
Tue Jan 21, 2020 8:05 am
Research in heterogeneity: New paper about patterns discrimination

Last post by frodo « Tue Jan 21, 2020 1:23 am
Posted in MS Etiology and Pathogenesis
Replies: 1
by frodo » Tue Jan 21, 2020 1:18 am » in MS Etiology and Pathogenesis

First post

New paper about discriminating the four pathological patterns:

The main idea is that there are four patterns of MS (one of them, IV very rare and...

Last post

Papers about tests for discriminating the patterns

- September 2019 : Multiplexed imaging of immune cells in staged multiple sclerosis lesions by...

1 Replies

22 Views

Last post by frodo
Tue Jan 21, 2020 1:23 am
icky lab results

Last post by jimmylegs « Mon Jan 20, 2020 1:00 pm
Posted in Daily Life
Replies: 3
by jimmylegs » Mon Oct 28, 2019 3:37 pm » in Daily Life

First post

welp i've been feeling a bit on the crap side and some of the answers are coming in now. the main news so far is low normal serum magnesium. looks...

Last post

great news from the lab :D way better zinc and ferritin status after corrective efforts in nov dec and early jan. improved zinc-copper ratio, with...

3 Replies

738 Views

Last post by jimmylegs
Mon Jan 20, 2020 1:00 pm
20% off at Vitacost.com

Last post by NHE « Mon Jan 20, 2020 9:49 am
Posted in Shopping

by NHE » Mon Jan 20, 2020 9:49 am » in Shopping

20% off at Vitacost.com

Save 20% off on all supplements, vitamins and herbs.

Use promo code: YOURHEALTH20
Expires 1/22/20 at 9 AM ET.

0 Replies

6 Views

Last post by NHE
Mon Jan 20, 2020 9:49 am
Biomarkers. Response to Fingolimod can be predicted.

Last post by frodo « Mon Jan 20, 2020 9:09 am
Posted in MS Etiology and Pathogenesis
Replies: 1
by frodo » Thu Apr 19, 2018 12:31 pm » in MS Etiology and Pathogenesis

First post

Predicting therapeutic response to fingolimod treatment in multiple sclerosis patients

Summary

Fingolimod, an orally active immunomodulatory...

Last post

Combinatorial allosteric modulation of agonist response in a self-interacting G-protein coupled receptor

The structural plasticity of G-protein...

1 Replies

753 Views

Last post by frodo
Mon Jan 20, 2020 9:09 am
Two new reports about EBV

Last post by frodo « Mon Jan 20, 2020 8:18 am
Posted in MS Etiology and Pathogenesis

by frodo » Mon Jan 20, 2020 8:18 am » in MS Etiology and Pathogenesis

The interaction of Multiple Sclerosis risk loci with Epstein-Barr virus phenotypes implicates the virus in pathogenesis

Conclusion

We believe...

0 Replies

15 Views

Last post by frodo
Mon Jan 20, 2020 8:18 am
Reports about the CSF toxicity

Last post by frodo « Mon Jan 20, 2020 4:40 am
Posted in MS Etiology and Pathogenesis
Replies: 2
by frodo » Sat Dec 30, 2017 4:25 am » in MS Etiology and Pathogenesis

First post

I am collecting here some of the studies about the CSF toxicity. One of the most interesting studies of the previous years was the possibility of...

Last post

Epstein Barr virus nuclear antigen 1 (EBNA-1) peptides recognized by adult multiple sclerosis patient sera induce neurologic symptoms in a murine...

2 Replies

1082 Views

Last post by frodo
Mon Jan 20, 2020 4:40 am
Relationship between MS and type-1 diabetes

Last post by frodo « Mon Jan 20, 2020 4:25 am
Posted in MS Etiology and Pathogenesis
Replies: 2
by frodo » Mon Jan 13, 2020 12:52 am » in MS Etiology and Pathogenesis

First post

Type-1 diabetes is the most common diabetes in children and autoimmune. These people are three-times more prone to develop MS than the general...

Last post

Not always MS and type1 diabetes are related. But MS could be more than one disease, and maybe a subtype is related.

An ancestral retroviral...

2 Replies

50 Views

Last post by frodo
Mon Jan 20, 2020 4:25 am
Air pollution

Last post by Petr75 « Mon Jan 20, 2020 12:59 am
Posted in General Discussion
Replies: 2
by Petr75 » Fri May 10, 2019 11:18 am » in General Discussion

First post

2019 Apr 5
Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, China
Emerging role of air...

Last post

2020 Jan 18
Afyonkarahisar University of Health Sciences, Department of Neurology, Afyon, Turkey
Air pollution, a possible risk factor for multiple...

2 Replies

238 Views

Last post by Petr75
Mon Jan 20, 2020 12:59 am
Lassman review for 2019. Top four MS papers.

Last post by frodo « Mon Jan 20, 2020 12:51 am
Posted in MS Etiology and Pathogenesis

by frodo » Mon Jan 20, 2020 12:51 am » in MS Etiology and Pathogenesis

1. Neuronal vulnerability and multilineage diversity in multiple sclerosis (Schirmer et al 2019)

The study supports the importance of meningeal...

0 Replies

16 Views

Last post by frodo
Mon Jan 20, 2020 12:51 am
all things magnesium

Last post by jimmylegs « Sun Jan 19, 2020 6:43 am
Posted in Natural Approach
Replies: 228
by Shayk » Mon Mar 13, 2006 6:00 pm » in Natural Approach
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Hi all

I accidentally happened upon this bit of info and thought it was interesting. It definitely suggests that magnesium operates like a statin....

Last post

Severe hypermagnesemia induced by magnesium oxide ingestion: a case series (2019)
fft:

Abstract
Hypermagnesemia is generally considered an...
228 Replies

42171 Views

Last post by jimmylegs
Sun Jan 19, 2020 6:43 am
Thoracic cavity venous flow

Last post by violin « Sat Jan 18, 2020 7:50 pm
Posted in Chronic Cerebrospinal Venous Insufficiency (CCSVI)
Replies: 2
by Petr75 » Mon Oct 28, 2019 1:00 am » in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

First post

2019 Oct
T. Tucker Inc., Ottawa, Ontario, Canada
Fluid dynamics of thoracic cavity venous flow in multiple sclerosis.

Abstract
This paper...

Last post

This article is so important! Thank you. Who is the author, Tucker? He’s in Canada? Super important for the many Canadians with MS.
Maybe call it...

2 Replies

181 Views

Last post by violin
Sat Jan 18, 2020 7:50 pm
GHEE offers many health benefits...

Last post by ElliotB « Sat Jan 18, 2020 4:48 pm
Posted in General Discussion

by ElliotB » Sat Jan 18, 2020 4:48 pm » in General Discussion

I switched to ghee (a form of clarified butter) from regular oils a couple of years ago because of the numerous health benefits it offers. Aside from...

0 Replies

41 Views

Last post by ElliotB
Sat Jan 18, 2020 4:48 pm
Diet

Last post by Petr75 « Sat Jan 18, 2020 5:58 am
Posted in General Discussion
Replies: 16
by Petr75 » Wed Apr 17, 2019 9:57 am » in General Discussion
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All I found out now is here

Last post

2019 Dec 3
Section for Sport Science, Department of Public Health, Aarhus University, Aarhus, Denmark
Is diet associated with physical capacity and...
16 Replies

1154 Views

Last post by Petr75
Sat Jan 18, 2020 5:58 am
Riding Amtrak in a wheelchair? $25,000!!!

Last post by NHE « Fri Jan 17, 2020 5:15 pm
Posted in Daily Life

by NHE » Fri Jan 17, 2020 5:15 pm » in Daily Life

Amtrak Asks Two People Who Use Wheelchairs To Pay $25,000 For A Ride

It costs just $16 to buy a one-way ticket on the Amtrak train from Chicago...

0 Replies

26 Views

Last post by NHE
Fri Jan 17, 2020 5:15 pm
personalized medicine for MS

Last post by frodo « Fri Jan 17, 2020 9:31 am
Posted in MS Etiology and Pathogenesis
Replies: 3
by frodo » Wed Nov 06, 2019 4:25 am » in MS Etiology and Pathogenesis

First post

Thanks to ms-uk for the review

New genetic markers may make prognosis clearer

The original paper:

Early complement genes are associated with...

Last post

Pre-treatment T-cell subsets associate with fingolimod treatment responsiveness in multiple sclerosis

Abstract

Biomarkers predicting fingolimod...

3 Replies

164 Views

Last post by frodo
Fri Jan 17, 2020 9:31 am
Tropospheric ozone

Last post by Petr75 « Fri Jan 17, 2020 8:05 am
Posted in General Discussion
Replies: 69
by Petr75 » Mon Jan 30, 2017 11:35 am » in General Discussion
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Hello friends, I ask for opinion ..

I dare theory
Ozone as a possible cause of MS

What's going on?
wiki

Possible clues:

New Guinea and MS...

Last post

2019 Nov
Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
Assessing Adverse Health Effects of Long-Term Exposure to Low Levels of...
69 Replies

7948 Views

Last post by Petr75
Fri Jan 17, 2020 8:05 am
A University of Regina researcher believes 3 proteins may be key to treating multiple sclerosis

Last post by frodo « Fri Jan 17, 2020 6:44 am
Posted in Drug Pipeline
Replies: 1
by 81Charger » Tue Oct 08, 2019 7:19 am » in Drug Pipeline

First post

Heidi Atter · CBC News · Posted: Oct 06, 2019 5:00 PM CT | Last Updated: October 6

Researcher Josef Buttigieg has always been interested in how...

Last post

This mouse with multiple sclerosis could not move its hind legs or tail and had only partial movements of its front legs before beginning treatment...

1 Replies

596 Views

Last post by frodo
Fri Jan 17, 2020 6:44 am
BMI

Last post by Petr75 « Fri Jan 17, 2020 3:51 am
Posted in General Discussion
Replies: 2
by Petr75 » Wed May 29, 2019 8:55 am » in General Discussion

First post

2019 Apr 21
Multiple Sclerosis Research Center; Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran
The relationship between...

Last post

2020 Jan 14
From the Preventive Neurology Unit (B.M.J., A.J.N., G.G., R.D.), Wolfson Institute of Preventive Medicine, Barts and Queen Mary...

2 Replies

188 Views

Last post by Petr75
Fri Jan 17, 2020 3:51 am
Safety vs. eficacy for some approved drugs

Last post by frodo « Fri Jan 17, 2020 3:08 am
Posted in General Discussion

by frodo » Fri Jan 17, 2020 3:08 am » in General Discussion

I have found this image very telling.

Watching this layout, I don't understand why not everybody is on Rituxan (nor why it is not approved)...

0 Replies

26 Views

Last post by frodo
Fri Jan 17, 2020 3:08 am
Review: Eficacy vs. safety for some approved drugs

Last post by frodo « Fri Jan 17, 2020 2:54 am
Posted in Drug Pipeline

by frodo » Fri Jan 17, 2020 2:54 am » in Drug Pipeline

I have found this image very interesting. Maybe you also will:

Source:

0 Replies

30 Views

Last post by frodo
Fri Jan 17, 2020 2:54 am
IGM+ MS could be different from normal MS

Last post by frodo « Fri Jan 17, 2020 2:42 am
Posted in MS Etiology and Pathogenesis
Replies: 1
by frodo » Thu Oct 31, 2019 11:35 am » in MS Etiology and Pathogenesis

First post

The oligoclonal bands in MS are IgG bands. There is a subset of patients with another immunoglobulin, IGM, that have a worse prognosis.

This paper...

Last post

Immunoglobulin M oligoclonal bands: Biomarker of targetable inflammation in primary progressive multiple sclerosis

Objective

To identify a...

1 Replies

199 Views

Last post by frodo
Fri Jan 17, 2020 2:42 am
Bioness l300 for sale

Last post by Reddirtgal22 « Thu Jan 16, 2020 8:42 pm
Posted in Introductions

by Reddirtgal22 » Thu Jan 16, 2020 8:42 pm » in Introductions

Hi. I’m new to the forum/community.
My name is Tina Jones. I was diagnosed 20 years ago this month and I have a Bioness l300 in excellent working...

0 Replies

22 Views

Last post by Reddirtgal22
Thu Jan 16, 2020 8:42 pm
Hello

Last post by Zyklon « Thu Jan 16, 2020 10:57 am
Posted in Introductions
Replies: 292
by Zyklon » Tue Apr 18, 2017 3:03 pm » in Introductions
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Hello ThisIsMS,

Sorry for my English, not my mother tongue. I am a 33 years old man from Turkey.

Disclaimer: This is just my long story. Always...

Last post

My regimen is almost the same. Tests and yearly MRI in the next month.
292 Replies

29421 Views

Last post by Zyklon
Thu Jan 16, 2020 10:57 am
Nose-to-brain

Last post by Petr75 « Thu Jan 16, 2020 7:32 am
Posted in General Discussion

by Petr75 » Thu Jan 16, 2020 7:32 am » in General Discussion

2020 Jan 14
Laboratory of Pharmacology, Faculty of Pharmacy, University of Coimbra, Pólo das Ciências da Saúde, Portugal
Nose-to-brain Delivery of...

0 Replies

39 Views

Last post by Petr75
Thu Jan 16, 2020 7:32 am
MRI is clear but been having symptoms for months

Last post by Ilovecoffee « Wed Jan 15, 2020 9:55 pm
Posted in Undiagnosed
Replies: 5
by Ilovecoffee » Mon Jan 13, 2020 11:31 am » in Undiagnosed

First post

I wanted to know if it is possible to have a clear MRI and still have MS? Could it be something else? I’ve been dealing with symptoms on and off for...

Last post

Thanks, I will definitely ask for a copy of the report. Unfortunately, I won’t be able to speak with the doctor until my follow up appointment in a...

5 Replies

89 Views

Last post by Ilovecoffee
Wed Jan 15, 2020 9:55 pm
Cardiovascular diseases

Last post by Petr75 « Wed Jan 15, 2020 8:45 am
Posted in General Discussion

by Petr75 » Wed Jan 15, 2020 8:45 am » in General Discussion

2019
Moscow State University of Medicine and Dentistry named after A.I. Evdokimov, Moscow, Russia
Comorbid pathology of the cardiovascular system in...

0 Replies

37 Views

Last post by Petr75
Wed Jan 15, 2020 8:45 am
Ms artificially induced in humans

Last post by frodo « Wed Jan 15, 2020 4:15 am
Posted in MS Etiology and Pathogenesis
Replies: 1
by frodo » Wed Jan 15, 2020 4:09 am » in MS Etiology and Pathogenesis

First post

Sometimes some MS patients get a kind of artificially induced MS while they are treated for other conditions. There are several reports about it...

Last post

Well. Not the same but I have found a paper in which they describe the action of TNF in mice, similar to the previous auto-antibody.

TNFR2 limits...

1 Replies

38 Views

Last post by frodo
Wed Jan 15, 2020 4:15 am
Type 1 diabetes (T1D) and multiple sclerosis

Last post by frodo « Wed Jan 15, 2020 4:02 am
Posted in General Discussion
Replies: 1
by Petr75 » Thu Jan 09, 2020 4:23 am » in General Discussion

First post

2020 Jan 7
Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences, Tehran, Iran
Identification of...

Last post

It is interesting thay they recommend different drugs than for normal MS (azathioprine, melatonin, resveratrol, and geldanamycin). They sound safer...

1 Replies

66 Views

Last post by frodo
Wed Jan 15, 2020 4:02 am

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