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Levetiracetam

Last post by Petr75 « Tue Jul 07, 2020 11:24 am
Posted in General Discussion

by Petr75 » Tue Jul 07, 2020 11:24 am » in General Discussion

2020 Jun 17
Rehabilitation Unit, Mons. L. Novarese Hospital, Moncrivello, Vercelli, Italy
Efficacy of Levetiracetam on Upper Limb Movement in...

0 Replies

9 Views

Last post by Petr75
Tue Jul 07, 2020 11:24 am
PI 3-kinase Delta

Last post by Petr75 « Tue Jul 07, 2020 11:15 am
Posted in General Discussion

by Petr75 » Tue Jul 07, 2020 11:15 am » in General Discussion

2020 Jun 17
John Van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK
PI 3-kinase Delta...

0 Replies

7 Views

Last post by Petr75
Tue Jul 07, 2020 11:15 am
NLRP3

Last post by Petr75 « Mon Jul 06, 2020 8:07 am
Posted in General Discussion

by Petr75 » Mon Jul 06, 2020 8:07 am » in General Discussion

2020 Jun 13
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno...

0 Replies

15 Views

Last post by Petr75
Mon Jul 06, 2020 8:07 am
Aquatic Therapy

Last post by Petr75 « Sun Jul 05, 2020 10:23 pm
Posted in General Discussion

by Petr75 » Sun Jul 05, 2020 10:23 pm » in General Discussion

2020 Jun 14.
University of Washington School of Medicine
Aquatic Therapy in Contemporary Neurorehabilitation: An Update

Abstract

Aquatic...

0 Replies

14 Views

Last post by Petr75
Sun Jul 05, 2020 10:23 pm
Pentraxin 3

Last post by Petr75 « Sun Jul 05, 2020 1:25 am
Posted in General Discussion

by Petr75 » Sun Jul 05, 2020 1:25 am » in General Discussion

2020 Jun 10
Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, 81 Meishan Road, Hefei, Anhui, Anhui...

0 Replies

28 Views

Last post by Petr75
Sun Jul 05, 2020 1:25 am
Lipids, Lymphocytes, and Vitamin D

Last post by Petr75 « Sat Jul 04, 2020 10:17 pm
Posted in General Discussion

by Petr75 » Sat Jul 04, 2020 10:17 pm » in General Discussion

2020
Department of Biochemistry, College of Agricultural and Life Sciences, University of Wisconsin-Madison
Multiple Sclerosis: Lipids, Lymphocytes,...

0 Replies

22 Views

Last post by Petr75
Sat Jul 04, 2020 10:17 pm
MicroRNA miR-22

Last post by Petr75 « Sat Jul 04, 2020 5:40 am
Posted in General Discussion

by Petr75 » Sat Jul 04, 2020 5:40 am » in General Discussion

2020 Jun 9
Shanghai Institute of Rheumatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, China
The MicroRNA miR-22 Represses...

0 Replies

23 Views

Last post by Petr75
Sat Jul 04, 2020 5:40 am
Formin-like 1

Last post by Petr75 « Fri Jul 03, 2020 12:01 pm
Posted in General Discussion

by Petr75 » Fri Jul 03, 2020 12:01 pm » in General Discussion

2020 Jun 8
Department of Biomedical Research, National Jewish Health, Denver
Formin-like 1 Mediates Effector T Cell Trafficking to Inflammatory...

0 Replies

18 Views

Last post by Petr75
Fri Jul 03, 2020 12:01 pm
Diroximel fumarate phase III study

Last post by NHE « Wed Jul 01, 2020 6:18 am
Posted in Vumerity (diroximel fumarate)

by NHE » Wed Jul 01, 2020 6:18 am » in Vumerity (diroximel fumarate)

Diroximel Fumarate Demonstrates an Improved Gastrointestinal Tolerability Profile Compared With Dimethyl Fumarate in Patients With...

0 Replies

26 Views

Last post by NHE
Wed Jul 01, 2020 6:18 am
FDA approves generic fingolimod

Last post by NHE « Tue Jun 30, 2020 8:35 am
Posted in Gilenya

by NHE » Tue Jun 30, 2020 8:35 am » in Gilenya

FDA Approves Generic Versions of Gilenya
December 6, 2019

On December 5, 2019, the United States Food and Drug Administration (FDA) announced...

0 Replies

29 Views

Last post by NHE
Tue Jun 30, 2020 8:35 am
Bafiertam offers a lower dosage vs. Tecfidera

Last post by NHE « Tue Jun 30, 2020 8:26 am
Posted in Bafiertam (monomethyl fumarate)

by NHE » Tue Jun 30, 2020 8:26 am » in Bafiertam (monomethyl fumarate)

A lower dose of Bafiertam as compared to Tecfidera may lead to fewer GI side effects, but this has yet to be clinically evaluated.

Bafiertam is...

0 Replies

22 Views

Last post by NHE
Tue Jun 30, 2020 8:26 am
Vumerity may have less GI side effects.

Last post by NHE « Tue Jun 30, 2020 8:07 am
Posted in Vumerity (diroximel fumarate)

by NHE » Tue Jun 30, 2020 8:07 am » in Vumerity (diroximel fumarate)

There may be less gastrointestinal symptoms with Vumerity as compared to Tecfidera.

The early findings, on gastrointestinal treatment-emergent...

0 Replies

26 Views

Last post by NHE
Tue Jun 30, 2020 8:07 am
New treatment forums, Vumerity and Bafiertam

Last post by NHE « Tue Jun 30, 2020 5:57 am
Posted in General Discussion

by NHE » Tue Jun 30, 2020 5:57 am » in General Discussion

Vumerity:

Bafiertam:

Both drugs are analogs of Tecfidera.

0 Replies

55 Views

Last post by NHE
Tue Jun 30, 2020 5:57 am
Bafiertam prescribing information

Last post by NHE « Tue Jun 30, 2020 5:46 am
Posted in Bafiertam (monomethyl fumarate)

by NHE » Tue Jun 30, 2020 5:46 am » in Bafiertam (monomethyl fumarate)

Bafiertam prescribing information.

More info at

0 Replies

18 Views

Last post by NHE
Tue Jun 30, 2020 5:46 am
Vumerity prescribing information

Last post by NHE « Tue Jun 30, 2020 5:28 am
Posted in Vumerity (diroximel fumarate)

by NHE » Tue Jun 30, 2020 5:28 am » in Vumerity (diroximel fumarate)

Vumerity prescribing information.

More info at

0 Replies

18 Views

Last post by NHE
Tue Jun 30, 2020 5:28 am
Two new FDA approvals. Vumerity and Bafiertam. Tecfidera bioequivalents.

Last post by frodo « Tue Jun 30, 2020 3:02 am
Posted in Tecfidera (BG-12, dimethyl fumarate)

by frodo » Tue Jun 30, 2020 3:02 am » in Tecfidera (BG-12, dimethyl fumarate)

Two new FDA approvals. Both are bioequivalents to Dymethyl fumarate / Tecfidera.

Diroximel fumerate (Vumerity). Approved by the FDA in October of...

0 Replies

25 Views

Last post by frodo
Tue Jun 30, 2020 3:02 am
Highly active MS and specific treatment

Last post by frodo « Tue Jun 30, 2020 12:37 am
Posted in MS Etiology and Pathogenesis

by frodo » Tue Jun 30, 2020 12:37 am » in MS Etiology and Pathogenesis

It is not an official but regulatory agencies considered the highly active MS (HAMS) separated from the rest in their approval processes for...

0 Replies

43 Views

Last post by frodo
Tue Jun 30, 2020 12:37 am
Cortical Grey Matter Hypoxia in MS

Last post by frodo « Tue Jun 30, 2020 12:05 am
Posted in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

by frodo » Tue Jun 30, 2020 12:05 am » in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

Investigating the Relationship Between Cortical Grey Matter Hypoxia and Disability in Multiple Sclerosis

Abstract

Multiple sclerosis (MS) is a...

0 Replies

44 Views

Last post by frodo
Tue Jun 30, 2020 12:05 am
Hippotherapy

Last post by Petr75 « Mon Jun 29, 2020 11:06 am
Posted in General Discussion

by Petr75 » Mon Jun 29, 2020 11:06 am » in General Discussion

2020 May 26
Laboratory of Human Motion Analysis, Faculty of Physical Education, University of Brasilia, Brazil
Effect of Hippotherapy on Walking...

0 Replies

28 Views

Last post by Petr75
Mon Jun 29, 2020 11:06 am
Microglia are the culprits for slowly expanding lesions

Last post by frodo « Mon Jun 29, 2020 12:17 am
Posted in MS Etiology and Pathogenesis

by frodo » Mon Jun 29, 2020 12:17 am » in MS Etiology and Pathogenesis

Slowly expanding lesions are suspected to be the cause of the MS progressive phase. Microglia and macrophages are cells that look similar and were...

0 Replies

24 Views

Last post by frodo
Mon Jun 29, 2020 12:17 am
biomarkers review 2020 and more fingers pointing to EBV

Last post by frodo « Mon Jun 29, 2020 12:11 am
Posted in MS Etiology and Pathogenesis

by frodo » Mon Jun 29, 2020 12:11 am » in MS Etiology and Pathogenesis

Molecular Biomarkers in the Cerebrospinal Fluid in Multiple Sclerosis

Multiple sclerosis (MS) is a chronic autoimmune disease affecting the spinal...

0 Replies

25 Views

Last post by frodo
Mon Jun 29, 2020 12:11 am
DCLK1

Last post by Petr75 « Sat Jun 27, 2020 11:30 am
Posted in General Discussion

by Petr75 » Sat Jun 27, 2020 11:30 am » in General Discussion

2020 May 22
Atatürk University, Faculty of Medicine, Department of Neurology, Erzurum, Turkey
DCLK-1 LEVEL IN MULTIPLE SCLEROSIS PATIENTS AND ITS...

0 Replies

30 Views

Last post by Petr75
Sat Jun 27, 2020 11:30 am
Three new genetic variants of MS

Last post by frodo « Thu Jun 25, 2020 1:33 am
Posted in MS Etiology and Pathogenesis

by frodo » Thu Jun 25, 2020 1:33 am » in MS Etiology and Pathogenesis

Neurological phenotypes in patients with NLRP3-, MEFV-, and TNFRSF1A low-penetrance variants

Background

Neurological manifestations and the...

0 Replies

37 Views

Last post by frodo
Thu Jun 25, 2020 1:33 am
The lancet. Open call for using NFL in diagnosis and monitoring

Last post by frodo « Thu Jun 25, 2020 1:26 am
Posted in MS Etiology and Pathogenesis

by frodo » Thu Jun 25, 2020 1:26 am » in MS Etiology and Pathogenesis

Neurofilament light in blood. What more is needed for clinical implementation?

Cerebrospinalfluid (CSF) neurofilament light (NfL) is the best...

0 Replies

25 Views

Last post by frodo
Thu Jun 25, 2020 1:26 am
Thesis: The endothelial angiopoietin-Tie signaling pathway

Last post by frodo « Tue Jun 23, 2020 8:57 am
Posted in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

by frodo » Tue Jun 23, 2020 8:57 am » in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

A new link between MS and the vascular system and angiogenesis

Overall, this thesis provides insight into the function of Tie1 and Ang2. Our...

0 Replies

32 Views

Last post by frodo
Tue Jun 23, 2020 8:57 am
Next DMTs to come

Last post by frodo « Tue Jun 23, 2020 8:52 am
Posted in Drug Pipeline

by frodo » Tue Jun 23, 2020 8:52 am » in Drug Pipeline

Ozanimod, laquinimod, BTK inhibitors (fenebrutinib, ibrutinib, and evobrutinib), Ibudilast, Lipoic acid and (maybe) Biotin.

Source:

Emerging...

0 Replies

42 Views

Last post by frodo
Tue Jun 23, 2020 8:52 am
Biotin treatment can turn PPMS into relapsing

Last post by frodo « Tue Jun 23, 2020 8:46 am
Posted in MS Etiology and Pathogenesis

by frodo » Tue Jun 23, 2020 8:46 am » in MS Etiology and Pathogenesis

There are contradicting reports on this topic. See for instance

Relapses During High-Dose Biotin Treatment in Progressive Multiple Sclerosis: a...

0 Replies

40 Views

Last post by frodo
Tue Jun 23, 2020 8:46 am
Automatic segmentation of different lesion types

Last post by frodo « Tue Jun 23, 2020 8:44 am
Posted in MS Etiology and Pathogenesis

by frodo » Tue Jun 23, 2020 8:44 am » in MS Etiology and Pathogenesis

Identification of Multiple Sclerosis lesion subtypes and their quantitative assessments with EDSS using neuroimaging

Abstract

It would be...

0 Replies

17 Views

Last post by frodo
Tue Jun 23, 2020 8:44 am
STIR Imaging of Intracranial Disease

Last post by frodo « Tue Jun 23, 2020 8:34 am
Posted in MS Etiology and Pathogenesis

by frodo » Tue Jun 23, 2020 8:34 am » in MS Etiology and Pathogenesis

Postcontrast STIR imaging offers additional information, not obtained with other sequences:

Postcontrast STIR Imaging of Intracranial Disease...

0 Replies

16 Views

Last post by frodo
Tue Jun 23, 2020 8:34 am
TAOPATCH

Last post by Samtina « Sun Jun 21, 2020 10:22 pm
Posted in General Discussion

by Samtina » Sun Jun 21, 2020 10:22 pm » in General Discussion

Has anyone here tried or of the Taopatch? My partner has been using 5hem for 8 days now. He is in a wheelchair for the past 12 years. He fights with...

0 Replies

207 Views

Last post by Samtina
Sun Jun 21, 2020 10:22 pm
FES device questions

Last post by Jaded « Sun Jun 21, 2020 5:37 am
Posted in General Discussion

by Jaded » Sun Jun 21, 2020 5:37 am » in General Discussion

Hi

So after many years of foot drop, I mentioned to my new neuro (thankfully a lovely lady who listens) that I was having walking problems. To be...

0 Replies

179 Views

Last post by Jaded
Sun Jun 21, 2020 5:37 am
Sleep

Last post by Petr75 « Sun Jun 21, 2020 1:23 am
Posted in General Discussion

by Petr75 » Sun Jun 21, 2020 1:23 am » in General Discussion

2020 May 18
Center of Affective, Stress and Sleep Disorders (ZASS), University of Basel, Psychiatric Clinic, Basel, Switzerland
Better Objective...

0 Replies

134 Views

Last post by Petr75
Sun Jun 21, 2020 1:23 am
Mg, Zn, Vit D and hypertension

Last post by jimmylegs « Sat Jun 20, 2020 8:27 am
Posted in Natural Approach

by jimmylegs » Sat Jun 20, 2020 8:27 am » in Natural Approach

OT re MS, but the regimen details looked interesting:

Increasing quality of life in pulmonary arterial hypertension: is there a role for nutrition?...

0 Replies

195 Views

Last post by jimmylegs
Sat Jun 20, 2020 8:27 am
Hyperbaric Oxygen Therapy

Last post by Petr75 « Sat Jun 20, 2020 2:24 am
Posted in General Discussion

by Petr75 » Sat Jun 20, 2020 2:24 am » in General Discussion

2020 Apr 29
Institute of Biomedical and Clinical Sciences, College of Medicine & Healthcare, University of Exeter, Exeter, UK; Royal Devon and Exeter...

0 Replies

138 Views

Last post by Petr75
Sat Jun 20, 2020 2:24 am
Article on CCSVI in Veins and Lymphatics 2020; Volume 9:9053

Last post by ThisIsMA « Fri Jun 19, 2020 12:13 pm
Posted in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

by ThisIsMA » Fri Jun 19, 2020 12:13 pm » in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

Here is a link to a new article in Veins and Lymphatics 2020; Volume 9:9053. If someone else has already posted this, my apologies. I couldn't find...

0 Replies

206 Views

Last post by ThisIsMA
Fri Jun 19, 2020 12:13 pm
Neuroplasticity

Last post by Petr75 « Fri Jun 19, 2020 11:40 am
Posted in General Discussion

by Petr75 » Fri Jun 19, 2020 11:40 am » in General Discussion

2020 May 6
ToNIC, Toulouse NeuroImaging Center, Université de Toulouse, Inserm, UPS, France
Neuroplasticity and Brain Reorganization Associated With...

0 Replies

142 Views

Last post by Petr75
Fri Jun 19, 2020 11:40 am
Sugar on the brain.

Last post by NHE « Wed Jun 17, 2020 2:08 am
Posted in Diet

by NHE » Wed Jun 17, 2020 2:08 am » in Diet

The People's Pharmacy discuss the effects of sugar aging and on the brain with Dr. Elissa Epel, Dr. David Perlmutter and Dr. Austin Perlmutter.

How...

0 Replies

208 Views

Last post by NHE
Wed Jun 17, 2020 2:08 am
CBD helps with anxiety

Last post by NHE « Wed Jun 17, 2020 12:45 am
Posted in Medical Marijuana

by NHE » Wed Jun 17, 2020 12:45 am » in Medical Marijuana

Cannabidiol in Anxiety and Sleep: A Large Case Series
The Permanente Journal. 2019; 23:18-041.

Context: Cannabidiol (CBD) is one of many...

0 Replies

191 Views

Last post by NHE
Wed Jun 17, 2020 12:45 am
prognosis based in a blood test

Last post by frodo « Tue Jun 16, 2020 2:33 am
Posted in MS Etiology and Pathogenesis

by frodo » Tue Jun 16, 2020 2:33 am » in MS Etiology and Pathogenesis

Clues to prognosis in multiple sclerosis found in the blood

Neurofilament light (NfL) and microRNAs (miRNAs) can help to predict the course that...

0 Replies

187 Views

Last post by frodo
Tue Jun 16, 2020 2:33 am
Hint for a new NMO variant confused into the MS spectrum

Last post by frodo « Thu Jun 11, 2020 5:46 am
Posted in MS Etiology and Pathogenesis

by frodo » Thu Jun 11, 2020 5:46 am » in MS Etiology and Pathogenesis

After classifying atypical cases in four groups, the classical MS, anti-AQP4 and anti-MOG groups appear, but a fourth group unclassifiable also...

0 Replies

110 Views

Last post by frodo
Thu Jun 11, 2020 5:46 am
biomarker for response to interferon beta-1b

Last post by frodo « Tue Jun 09, 2020 2:38 am
Posted in MS Etiology and Pathogenesis

by frodo » Tue Jun 09, 2020 2:38 am » in MS Etiology and Pathogenesis

A long-term follow-up study on biochemical and clinical biomarkers of response to interferon beta-1b treatment in relapsing-remitting multiple...

0 Replies

105 Views

Last post by frodo
Tue Jun 09, 2020 2:38 am
Comparison of DMTs: Alemtuzumab and NTZ better than others.

Last post by frodo « Tue Jun 09, 2020 2:32 am
Posted in General Discussion

by frodo » Tue Jun 09, 2020 2:32 am » in General Discussion

... reported on similar conclusions that DMF and FTY have similar effectiveness and out-perform injectable therapies; and alemtuzumab and NTZ are...

0 Replies

124 Views

Last post by frodo
Tue Jun 09, 2020 2:32 am
MSAA Assistance

Last post by NHE « Fri Jun 05, 2020 10:38 pm
Posted in Daily Life

by NHE » Fri Jun 05, 2020 10:38 pm » in Daily Life

The Multiple Sclerosis Association of America (MSAA) offers several assistance programs to help people with MS acquire basic assistance products like...

0 Replies

128 Views

Last post by NHE
Fri Jun 05, 2020 10:38 pm
Vegas CCSVI treatment healthcare providers

Last post by sin319 « Fri Jun 05, 2020 2:39 pm
Posted in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

by sin319 » Fri Jun 05, 2020 2:39 pm » in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

Hello all!

I was hoping one of you might know of a healthcare provider in or close to Las Vegas, NV who can perform CCSVI treatment?

Any help is...

0 Replies

124 Views

Last post by sin319
Fri Jun 05, 2020 2:39 pm
Vegas CCSVI healthcare providers

Last post by sin319 « Fri Jun 05, 2020 8:59 am
Posted in General Discussion

by sin319 » Fri Jun 05, 2020 8:59 am » in General Discussion

Hello all!

I was hoping one of you might know of a healthcare provider in or close to Las Vegas, NV who can perform CCSVI treatment?

Any help is...

0 Replies

114 Views

Last post by sin319
Fri Jun 05, 2020 8:59 am
CCSVI ten years later

Last post by frodo « Thu Jun 04, 2020 12:39 am
Posted in MS Etiology and Pathogenesis

by frodo » Thu Jun 04, 2020 12:39 am » in MS Etiology and Pathogenesis

Chronic cerebrospinal venous insufficiency, ten years after. New headlights on a venous disease that enriched the vascular world

Pdf available...

0 Replies

152 Views

Last post by frodo
Thu Jun 04, 2020 12:39 am
Fingolimod better than interferon beta and GA

Last post by frodo « Tue Jun 02, 2020 12:34 am
Posted in General Discussion

by frodo » Tue Jun 02, 2020 12:34 am » in General Discussion

Disability progression in relapse-free multiple sclerosis patients on fingolimod versus interferon-beta/glatiramer acetate

Abstract...

0 Replies

115 Views

Last post by frodo
Tue Jun 02, 2020 12:34 am
Four patterns of oligoclonal bands

Last post by frodo « Sat May 30, 2020 12:51 am
Posted in MS Etiology and Pathogenesis

by frodo » Sat May 30, 2020 12:51 am » in MS Etiology and Pathogenesis

Kappa Free Light Chains and IgG Combined in a Novel Algorithm for the Detection of Multiple Sclerosis

Abstract

Background :
It is well known...

0 Replies

125 Views

Last post by frodo
Sat May 30, 2020 12:51 am
increased risk of cardiovascular and cerebrovascular disease in MS

Last post by frodo « Fri May 29, 2020 6:31 am
Posted in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

by frodo » Fri May 29, 2020 6:31 am » in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

Evaluating the Risk of Macrovascular Events and Mortality Among People With Multiple Sclerosis in England

Abstract

Importance People with...

0 Replies

121 Views

Last post by frodo
Fri May 29, 2020 6:31 am
Biomarker: Antibodies in the patients’ cerebrospinal fluid are attracted to some peptides

Last post by frodo « Fri May 29, 2020 6:28 am
Posted in MS Etiology and Pathogenesis

by frodo » Fri May 29, 2020 6:28 am » in MS Etiology and Pathogenesis

Nanoimmunosensor based on atomic force spectroscopy to detect anti-myelin basic protein related to early-stage multiple sclerosis

Highlights

•...

0 Replies

111 Views

Last post by frodo
Fri May 29, 2020 6:28 am

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