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TNF demyelination considered as MS

Last post by frodo « Wed Feb 24, 2021 2:05 am
Posted in MS Etiology and Pathogenesis

by frodo » Wed Feb 24, 2021 2:05 am » in MS Etiology and Pathogenesis

TNF-α blockers-associated multiple sclerosis

Conclusion

Our study confirmed that the exposure to TNFα blockers can be associated to a broad...

0 Replies

37 Views

Last post by frodo
Wed Feb 24, 2021 2:05 am
α1-3Gal

Last post by Petr75 « Tue Feb 23, 2021 12:11 am
Posted in General Discussion

by Petr75 » Tue Feb 23, 2021 12:11 am » in General Discussion

2021 Feb 5
Centre de Recherche en Transplantation et Immunologie UMR 1064, INSERM, Université de Nantes, Nantes, France; Institut de Transplantation...

0 Replies

44 Views

Last post by Petr75
Tue Feb 23, 2021 12:11 am
Audiovestibular

Last post by Petr75 « Mon Feb 22, 2021 12:54 pm
Posted in General Discussion

by Petr75 » Mon Feb 22, 2021 12:54 pm » in General Discussion

2021 Feb 5
Department of Speech and Hearing, School of Clinical Therapies, College of Medicine and Health, University College Cork, Cork, Ireland...

0 Replies

58 Views

Last post by Petr75
Mon Feb 22, 2021 12:54 pm
Sleep is your superpower

Last post by NHE « Sat Feb 20, 2021 12:22 am
Posted in Daily Life

by NHE » Sat Feb 20, 2021 12:22 am » in Daily Life

TED Talk: Sleep is Your Superpower - Matthew Walker, UC Berkeley

0 Replies

57 Views

Last post by NHE
Sat Feb 20, 2021 12:22 am
Physical activity improves brain health

Last post by NHE « Thu Feb 18, 2021 2:36 am
Posted in Exercise and Physical Therapy

by NHE » Thu Feb 18, 2021 2:36 am » in Exercise and Physical Therapy

Prospective Analysis of Leisure-Time Physical Activity in Midlife and Beyond and Brain Damage on MRI in Older Adults
Neurology. 2021 Feb...

0 Replies

65 Views

Last post by NHE
Thu Feb 18, 2021 2:36 am
Visual evoked potentials facilitate MS diagnosis

Last post by NHE « Thu Feb 18, 2021 2:19 am
Posted in General Discussion

by NHE » Thu Feb 18, 2021 2:19 am » in General Discussion

Optic Nerve Topography in Multiple Sclerosis Diagnosis: The Utility of Visual Evoked Potentials
Neurology. 2021 Jan 26;96(4):e482-e490....

0 Replies

72 Views

Last post by NHE
Thu Feb 18, 2021 2:19 am
TREM2

Last post by Petr75 « Mon Feb 15, 2021 1:21 pm
Posted in General Discussion

by Petr75 » Mon Feb 15, 2021 1:21 pm » in General Discussion

2021 Jan 27
Skylar J Ferrara, Priya Chaudhary,
TREM2 is thyroid hormone regulated making the TREM2 pathway druggable with ligands for thyroid...

0 Replies

79 Views

Last post by Petr75
Mon Feb 15, 2021 1:21 pm
COVID Vaccine and MS

Last post by David1949 « Sun Feb 14, 2021 10:16 am
Posted in General Discussion

by David1949 » Sun Feb 14, 2021 10:16 am » in General Discussion

According to the National MS society's website people with MS should get the COVID vaccine . Although there are a few noteworthy comments.

Source...

0 Replies

281 Views

Last post by David1949
Sun Feb 14, 2021 10:16 am
Natural Products for Neurocognitive Disorders

Last post by NHE « Sat Feb 13, 2021 7:08 am
Posted in Natural Approach

by NHE » Sat Feb 13, 2021 7:08 am » in Natural Approach

Free book chapter in Alzheimer’s Disease: Drug Discovery.

Natural Products for Neurocognitive Disorders

0 Replies

88 Views

Last post by NHE
Sat Feb 13, 2021 7:08 am
Mesenchymal stem cells in progressive MS

Last post by NHE « Wed Feb 10, 2021 2:06 pm
Posted in Stem Cells

by NHE » Wed Feb 10, 2021 2:06 pm » in Stem Cells

Beneficial effects of autologous mesenchymal stem cell transplantation in active progressive multiple sclerosis
Brain. 2020 Dec...

0 Replies

215 Views

Last post by NHE
Wed Feb 10, 2021 2:06 pm
The lancet: More about the previous two epitopes

Last post by frodo « Mon Feb 08, 2021 11:02 am
Posted in MS Etiology and Pathogenesis

by frodo » Mon Feb 08, 2021 11:02 am » in MS Etiology and Pathogenesis

Serum markers of multiple sclerosis - a new approach

Optic neuritis (ON) typically manifests with the classical triad of subacute unilateral...

0 Replies

109 Views

Last post by frodo
Mon Feb 08, 2021 11:02 am
Biomarkers: Two epitopes predict ON evolution to MS

Last post by frodo « Mon Feb 08, 2021 10:55 am
Posted in MS Etiology and Pathogenesis

by frodo » Mon Feb 08, 2021 10:55 am » in MS Etiology and Pathogenesis

You can see what a epitope is at wikipedia:

Identification of two highly antigenic epitope markers predicting multiple sclerosis in optic neuritis...

0 Replies

130 Views

Last post by frodo
Mon Feb 08, 2021 10:55 am
plasmablast: 100% specificity

Last post by frodo « Mon Feb 08, 2021 10:51 am
Posted in MS Etiology and Pathogenesis

by frodo » Mon Feb 08, 2021 10:51 am » in MS Etiology and Pathogenesis

Plasmablast ( immature blood cells ) reported to have 36% sensivity and 100% specificity compared to other neurological diseases.

Summary...

0 Replies

95 Views

Last post by frodo
Mon Feb 08, 2021 10:51 am
Apolipoprotein D

Last post by Petr75 « Sun Feb 07, 2021 11:19 am
Posted in General Discussion

by Petr75 » Sun Feb 07, 2021 11:19 am » in General Discussion

2021 Jan 27
Department of Morphology and Cell Biology, University of Oviedo, Spain
Neuroprotective Effect of Apolipoprotein D in Cuprizone-Induced...

0 Replies

120 Views

Last post by Petr75
Sun Feb 07, 2021 11:19 am
Dural sinuses

Last post by Petr75 « Wed Feb 03, 2021 12:42 pm
Posted in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

by Petr75 » Wed Feb 03, 2021 12:42 pm » in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

2021 Jan 18
Center for Brain Immunology and Glia (BIG), Washington University in St. Louis, USA
Functional characterization of the dural sinuses as...

0 Replies

154 Views

Last post by Petr75
Wed Feb 03, 2021 12:42 pm
A unified view of multiple sclerosis

Last post by frodo « Sat Jan 30, 2021 3:48 am
Posted in MS Etiology and Pathogenesis

by frodo » Sat Jan 30, 2021 3:48 am » in MS Etiology and Pathogenesis

A unified view of multiple sclerosis

Abstract

The clinical course of multiple sclerosis (MS)is highly variable. To establish a standardized...

0 Replies

539 Views

Last post by frodo
Sat Jan 30, 2021 3:48 am
Dietary carotenoids reduce risk of Alzheimer's Disease

Last post by NHE « Fri Jan 29, 2021 5:05 am
Posted in Diet

by NHE » Fri Jan 29, 2021 5:05 am » in Diet

Dietary carotenoids related to risk of incident Alzheimer dementia (AD) and brain AD neuropathology: a community-based cohort of older adults
The...

0 Replies

369 Views

Last post by NHE
Fri Jan 29, 2021 5:05 am
Biomarkers: Two new ones related to EBV

Last post by frodo « Tue Jan 26, 2021 12:56 pm
Posted in MS Etiology and Pathogenesis

by frodo » Tue Jan 26, 2021 12:56 pm » in MS Etiology and Pathogenesis

Identification of two highly antigenic epitope markers predicting multiple sclerosis in optic neuritis patients

0 Replies

277 Views

Last post by frodo
Tue Jan 26, 2021 12:56 pm
Heparanome

Last post by Petr75 « Sat Jan 23, 2021 2:46 am
Posted in General Discussion

by Petr75 » Sat Jan 23, 2021 2:46 am » in General Discussion

2021 Jan 15
Department of Pharmacology and Toxicology, Jacob's School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA...

0 Replies

257 Views

Last post by Petr75
Sat Jan 23, 2021 2:46 am
Nature: MRI can show biological heterogeneity

Last post by frodo « Fri Jan 22, 2021 10:59 pm
Posted in MS Etiology and Pathogenesis

by frodo » Fri Jan 22, 2021 10:59 pm » in MS Etiology and Pathogenesis

Quantitative MRI phenotypes capture biological heterogeneity in multiple sclerosis patients

Abstract

Magnetization transfer ratio (MTR) and...

0 Replies

249 Views

Last post by frodo
Fri Jan 22, 2021 10:59 pm
Ibudilast for PPMS better than for SPMS

Last post by frodo « Fri Jan 22, 2021 10:52 pm
Posted in MS Etiology and Pathogenesis

by frodo » Fri Jan 22, 2021 10:52 pm » in MS Etiology and Pathogenesis

Response to ibudilast treatment according to progressive multiple sclerosis disease phenotype

Discussion

The impetus to study ibudilast in...

0 Replies

214 Views

Last post by frodo
Fri Jan 22, 2021 10:52 pm
Nasolacrimal transition time

Last post by Petr75 « Tue Jan 19, 2021 12:23 am
Posted in General Discussion

by Petr75 » Tue Jan 19, 2021 12:23 am » in General Discussion

2021 Jan 16
Department of Otolaryngology, Yozgat Bozok University School of Medicine, Yozgat, Turkey
Nasolacrimal transition time in patients with...

0 Replies

270 Views

Last post by Petr75
Tue Jan 19, 2021 12:23 am
PEGylation

Last post by Petr75 « Sat Jan 16, 2021 9:40 am
Posted in General Discussion

by Petr75 » Sat Jan 16, 2021 9:40 am » in General Discussion

2021 Jan 12
Department of Materials Science and Engineering, Drexel University, Philadelphia, USA
PEGylation enables subcutaneously administered...

0 Replies

259 Views

Last post by Petr75
Sat Jan 16, 2021 9:40 am
Vitamin D3's anti-inflammatory effect via IL-27 & TGF-B1

Last post by NHE « Thu Jan 14, 2021 2:09 am
Posted in Natural Approach

by NHE » Thu Jan 14, 2021 2:09 am » in Natural Approach

The impact of vitamin D3 intake on inflammatory markers in multiple sclerosis patients and their first-degree relatives

Background & aims: In our...

0 Replies

243 Views

Last post by NHE
Thu Jan 14, 2021 2:09 am
Covid 19 vaccine research

Last post by shadowfax « Wed Jan 13, 2021 12:43 pm
Posted in General Discussion

by shadowfax » Wed Jan 13, 2021 12:43 pm » in General Discussion

Seems Pfizer and its covid 19 vaccine partner Biontech have developed a varient of the vaccine that stops MS

0 Replies

295 Views

Last post by shadowfax
Wed Jan 13, 2021 12:43 pm
serum biomarkers: Phospholipids

Last post by frodo « Wed Jan 13, 2021 5:31 am
Posted in MS Etiology and Pathogenesis

by frodo » Wed Jan 13, 2021 5:31 am » in MS Etiology and Pathogenesis

Serum phospholipidomics reveals altered lipid profile and promising biomarkers in multiple sclerosis

Conclusion

From this study, we can...

0 Replies

233 Views

Last post by frodo
Wed Jan 13, 2021 5:31 am
Western lifestyle: Possible link to antibiotics consumption

Last post by frodo « Tue Jan 12, 2021 10:40 am
Posted in MS Etiology and Pathogenesis

by frodo » Tue Jan 12, 2021 10:40 am » in MS Etiology and Pathogenesis

Holistic solution to an old mystery : the global role of antibiotic consumption patterns in the spread of certain non-contagious diseases in EU...

0 Replies

258 Views

Last post by frodo
Tue Jan 12, 2021 10:40 am
Obstructive Malformations of the Internal Jugular Vein

Last post by frodo « Tue Jan 12, 2021 9:27 am
Posted in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

by frodo » Tue Jan 12, 2021 9:27 am » in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

Obstructive Malformations of the Internal Jugular Vein

Abstract

Obstructive malformations of the internal jugular veins represent a relatively...

0 Replies

306 Views

Last post by frodo
Tue Jan 12, 2021 9:27 am
New medical entity overlapping with MS: DAF

Last post by frodo « Tue Jan 12, 2021 9:05 am
Posted in MS Etiology and Pathogenesis

by frodo » Tue Jan 12, 2021 9:05 am » in MS Etiology and Pathogenesis

After NMO and anti-MOG, and following the non-autoimmune models of MS, it seems that there is a new entity entering the scene:

Demyelination with...

0 Replies

228 Views

Last post by frodo
Tue Jan 12, 2021 9:05 am
help us too walk no drugs or cutting head

Last post by Weneedhope « Tue Jan 12, 2021 4:56 am
Posted in General Discussion

by Weneedhope » Tue Jan 12, 2021 4:56 am » in General Discussion

hi all i found this

its look help walk ez

i hope it just the start this year thank you

0 Replies

262 Views

Last post by Weneedhope
Tue Jan 12, 2021 4:56 am
Hydroxychloroquine and Indapamide

Last post by Petr75 « Fri Jan 08, 2021 12:08 pm
Posted in General Discussion

by Petr75 » Fri Jan 08, 2021 12:08 pm » in General Discussion

2021 Jan 6
Hotchkiss Brain Institute and Department of Clinical Neurosciences, University of Calgary, Canada
Combination of Hydroxychloroquine and...

0 Replies

271 Views

Last post by Petr75
Fri Jan 08, 2021 12:08 pm
Sanjay Gupta: Build a Better Brain at Any Age

Last post by NHE « Thu Jan 07, 2021 3:49 am
Posted in Reading Nook

by NHE » Thu Jan 07, 2021 3:49 am » in Reading Nook

Dr. Sanjay Gupta is interviewed by Terry Gross on NPR's Fresh Air regarding his new book Keep Sharp: Build A Better Brain At Any Age.

0 Replies

268 Views

Last post by NHE
Thu Jan 07, 2021 3:49 am
Administration of CD4 + CD25 high CD127 - FoxP3 + Regulatory T Cells

Last post by Petr75 « Wed Jan 06, 2021 12:02 pm
Posted in Drug Pipeline

by Petr75 » Wed Jan 06, 2021 12:02 pm » in Drug Pipeline

2021 Jan 5
Department of Neurology, Medical University of Gdańsk, Gdańsk, Poland
Administration of CD4 + CD25 high CD127 - FoxP3 + Regulatory T...

0 Replies

298 Views

Last post by Petr75
Wed Jan 06, 2021 12:02 pm
Trauma

Last post by Petr75 « Wed Jan 06, 2021 9:30 am
Posted in General Discussion

by Petr75 » Wed Jan 06, 2021 9:30 am » in General Discussion

2021 Jan 4
University of Illinois at Urbana-Champaign Department of Comparative Biosciences, US
Early-life-trauma triggers interferon-β resistance...

0 Replies

220 Views

Last post by Petr75
Wed Jan 06, 2021 9:30 am
subtyping RRMS

Last post by frodo « Tue Jan 05, 2021 3:00 pm
Posted in MS Etiology and Pathogenesis

by frodo » Tue Jan 05, 2021 3:00 pm » in MS Etiology and Pathogenesis

Subtyping relapsing–remitting multiple sclerosis using structural MRI

Abstract
Background and purpose

Subtyping relapsing–remitting multiple...

0 Replies

185 Views

Last post by frodo
Tue Jan 05, 2021 3:00 pm
Curcumin increases BDNF and lowers COX2 in vivo

Last post by NHE « Tue Jan 05, 2021 4:58 am
Posted in Natural Approach

by NHE » Tue Jan 05, 2021 4:58 am » in Natural Approach

Curcumin Alters Neural Plasticity and Viability of Intact Hippocampal Circuits and Attenuates Behavioral Despair and COX-2 Expression in Chronically...

0 Replies

187 Views

Last post by NHE
Tue Jan 05, 2021 4:58 am
Hypoxia

Last post by Petr75 « Tue Dec 29, 2020 12:08 am
Posted in General Discussion

by Petr75 » Tue Dec 29, 2020 12:08 am » in General Discussion

2020 Dec 22
San Diego Biomedical Research Institute, US
Hypoxia in multiple sclerosis; is it the chicken or the egg?

Abstract

Over the past 50...

0 Replies

271 Views

Last post by Petr75
Tue Dec 29, 2020 12:08 am
Headaches

Last post by Petr75 « Sat Dec 26, 2020 4:01 am
Posted in General Discussion

by Petr75 » Sat Dec 26, 2020 4:01 am » in General Discussion

2020 Dec 8
Department of Neurology, The First Affiliated Hospital of Anhui Medical University, Hefei, China
The epidemiology of primary headaches in...

0 Replies

218 Views

Last post by Petr75
Sat Dec 26, 2020 4:01 am
Nicotinamide adenine dinucleotide (NAD + )

Last post by Petr75 « Sat Dec 26, 2020 1:36 am
Posted in General Discussion

by Petr75 » Sat Dec 26, 2020 1:36 am » in General Discussion

2020 Dec 4
Department of Neurology, The Second Hospital of Hebei Medical University, Shijiazhuang, China; Second Department of Neurology, Children's...

0 Replies

197 Views

Last post by Petr75
Sat Dec 26, 2020 1:36 am
Small extracellular vesicles

Last post by Petr75 « Sat Dec 26, 2020 1:25 am
Posted in General Discussion

by Petr75 » Sat Dec 26, 2020 1:25 am » in General Discussion

2020 Dec 4
Department of Immunology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Intranasal administration of...

0 Replies

168 Views

Last post by Petr75
Sat Dec 26, 2020 1:25 am
Serotonin

Last post by Petr75 « Thu Dec 24, 2020 12:28 pm
Posted in General Discussion

by Petr75 » Thu Dec 24, 2020 12:28 pm » in General Discussion

2020 Nov 2
Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, US
Multiple Sclerosis and Serotonin:...

0 Replies

191 Views

Last post by Petr75
Thu Dec 24, 2020 12:28 pm
A, D & vaccination

Last post by jimmylegs « Wed Dec 23, 2020 3:43 pm
Posted in Natural Approach

by jimmylegs » Wed Dec 23, 2020 3:43 pm » in Natural Approach

not ms, just interesting

Baseline Serum Vitamin A and D Levels Determine Benefit of Oral Vitamin A&D Supplements to Humoral Immune Responses...

0 Replies

159 Views

Last post by jimmylegs
Wed Dec 23, 2020 3:43 pm
venous diameter changes in MS

Last post by frodo « Tue Dec 22, 2020 12:37 pm
Posted in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

by frodo » Tue Dec 22, 2020 12:37 pm » in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

Venous Diameter Changes in Chronic Active Multiple Sclerosis Lesions

CONCLUSION
Our findings demonstrate venous narrowing in chronic active and...

0 Replies

161 Views

Last post by frodo
Tue Dec 22, 2020 12:37 pm
vascular problems in MS retina

Last post by frodo « Tue Dec 22, 2020 12:34 pm
Posted in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

by frodo » Tue Dec 22, 2020 12:34 pm » in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

Angiography with optical coherence tomography as a biomarker in multiple sclerosis

Conclusions

MS produces a decrease in retinal vascularization...

0 Replies

158 Views

Last post by frodo
Tue Dec 22, 2020 12:34 pm
Lipid profile

Last post by Petr75 « Tue Dec 22, 2020 5:17 am
Posted in General Discussion

by Petr75 » Tue Dec 22, 2020 5:17 am » in General Discussion

2020 Dec
Laboratorio de Neuroinmunoendocrinología, Departamento de Investigación Biomédica, Facultad de Medicina, Universidad Autónoma de Querétaro,...

0 Replies

209 Views

Last post by Petr75
Tue Dec 22, 2020 5:17 am
Prenatal Stress

Last post by Petr75 « Tue Dec 22, 2020 3:25 am
Posted in General Discussion

by Petr75 » Tue Dec 22, 2020 3:25 am » in General Discussion

2020 Dec 1
Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
Prenatal Stress Impairs Spinal Cord...

0 Replies

188 Views

Last post by Petr75
Tue Dec 22, 2020 3:25 am
Foot Drop rehabilitation

Last post by Petr75 « Tue Dec 22, 2020 1:03 am
Posted in Exercise and Physical Therapy

by Petr75 » Tue Dec 22, 2020 1:03 am » in Exercise and Physical Therapy

2020 Nov 28
College of Information Technology, United Arab Emirates University , Al Ain, UAE
Trends and Technologies in Rehabilitation of Foot Drop:...

0 Replies

148 Views

Last post by Petr75
Tue Dec 22, 2020 1:03 am
Herpes simplex virus

Last post by Petr75 « Tue Dec 22, 2020 12:07 am
Posted in MS Etiology and Pathogenesis

by Petr75 » Tue Dec 22, 2020 12:07 am » in MS Etiology and Pathogenesis

2020 Nov 19
Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China
Positive...

0 Replies

156 Views

Last post by Petr75
Tue Dec 22, 2020 12:07 am
zinc and infection

Last post by jimmylegs « Sun Dec 20, 2020 10:41 am
Posted in Natural Approach

by jimmylegs » Sun Dec 20, 2020 10:41 am » in Natural Approach

noted this one with interest, having endured candida infection as a kid followed by later lab-documented zinc deficiency, w associated consequences...

0 Replies

257 Views

Last post by jimmylegs
Sun Dec 20, 2020 10:41 am
Tolerogenic nanoparticles

Last post by Petr75 « Tue Dec 15, 2020 11:15 am
Posted in General Discussion

by Petr75 » Tue Dec 15, 2020 11:15 am » in General Discussion

2020 Nov 25
Department of Pathology, Boston University School of Medicine, Boston
Tolerogenic nanoparticles suppress central nervous system...

0 Replies

217 Views

Last post by Petr75
Tue Dec 15, 2020 11:15 am

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