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Ponesimod phase III trial vs. teriflunimide

Last post by NHE « Sun Apr 18, 2021 8:42 pm
Posted in Ponvory (ponesimod)

by NHE » Sun Apr 18, 2021 8:42 pm » in Ponvory (ponesimod)

Ponesimod Compared With Teriflunomide in Patients With Relapsing Multiple Sclerosis in the Active-Comparator Phase 3 OPTIMUM Study: A Randomized...

0 Replies

13 Views

Last post by NHE
Sun Apr 18, 2021 8:42 pm
Free Women's XXL cooling vest, no longer fits

Last post by savimavi « Sun Apr 18, 2021 6:52 am
Posted in Shopping

by savimavi » Sun Apr 18, 2021 6:52 am » in Shopping

I have a black women's size XXL cooling vest I no longer fit. I lost a lot of weight, and you don't feel the cooling unless it is snug. I have the...

0 Replies

21 Views

Last post by savimavi
Sun Apr 18, 2021 6:52 am
New treatment forum: Ponvory

Last post by NHE « Sun Apr 18, 2021 4:42 am
Posted in General Discussion

by NHE » Sun Apr 18, 2021 4:42 am » in General Discussion

Ponvory is an oral sphingosine 1-phosphate receptor modulator indicated for the
treatment of RRMS and active SPMS.

0 Replies

37 Views

Last post by NHE
Sun Apr 18, 2021 4:42 am
Therapeutic Potential of Ponesimod +/- Dimethyl Fumarate in EAE

Last post by NHE « Sun Apr 18, 2021 4:33 am
Posted in Ponvory (ponesimod)

by NHE » Sun Apr 18, 2021 4:33 am » in Ponvory (ponesimod)

Therapeutic Potential of Ponesimod Alone and in Combination with Dimethyl Fumarate in Experimental Models of Multiple Sclerosis
Innov Clin...

0 Replies

21 Views

Last post by NHE
Sun Apr 18, 2021 4:33 am
Ponesimod phase II trial

Last post by NHE « Sun Apr 18, 2021 3:57 am
Posted in Ponvory (ponesimod)

by NHE » Sun Apr 18, 2021 3:57 am » in Ponvory (ponesimod)

Oral ponesimod in relapsing-remitting multiple sclerosis: a randomised phase II trial
J Neurol Neurosurg Psychiatry. 2014 Nov;85(11):1198-208....

0 Replies

20 Views

Last post by NHE
Sun Apr 18, 2021 3:57 am
Ponvory prescribing information

Last post by NHE « Sun Apr 18, 2021 3:00 am
Posted in Ponvory (ponesimod)

by NHE » Sun Apr 18, 2021 3:00 am » in Ponvory (ponesimod)

Ponvory is a sphingosine 1-phosphate receptor modulator indicated for the
treatment of relapsing forms of multiple sclerosis (MS).

0 Replies

28 Views

Last post by NHE
Sun Apr 18, 2021 3:00 am
Immune Tolerance

Last post by Petr75 « Sat Apr 17, 2021 11:52 am
Posted in General Discussion

by Petr75 » Sat Apr 17, 2021 11:52 am » in General Discussion

2021 Mar 29
Department of Inflammation and Oncology, Amgen Research, Amgen Inc., South San Francisco, CA, United States
Emerging Therapeutics for...

0 Replies

26 Views

Last post by Petr75
Sat Apr 17, 2021 11:52 am
Review of neuroprotective therapies and remyelination strategies

Last post by DIM « Thu Apr 15, 2021 11:36 am
Posted in General Discussion

by DIM » Thu Apr 15, 2021 11:36 am » in General Discussion

0 Replies

67 Views

Last post by DIM
Thu Apr 15, 2021 11:36 am
what is your serum ferritin level telling you?

Last post by jimmylegs « Thu Apr 15, 2021 3:54 am
Posted in Natural Approach

by jimmylegs » Thu Apr 15, 2021 3:54 am » in Natural Approach

if you're going to work with minerals, make sure you're clear on what's really happening :)

Ferritin Is a Marker of Inflammation rather than Iron...

0 Replies

50 Views

Last post by jimmylegs
Thu Apr 15, 2021 3:54 am
Sex differences in MS

Last post by Scott1 « Tue Apr 13, 2021 5:42 pm
Posted in General Discussion

by Scott1 » Tue Apr 13, 2021 5:42 pm » in General Discussion

Finally! A really great scientist having a rant.

0 Replies

92 Views

Last post by Scott1
Tue Apr 13, 2021 5:42 pm
Rhythmic

Last post by Petr75 « Tue Apr 13, 2021 4:01 am
Posted in General Discussion

by Petr75 » Tue Apr 13, 2021 4:01 am » in General Discussion

2021 Apr 5
REVAL Rehabilitation Research Center, Faculty of Rehabilitation Sciences, Hasselt University, Hasselt, Belgium
Rhythmic interlimb...

0 Replies

66 Views

Last post by Petr75
Tue Apr 13, 2021 4:01 am
MCT oil helps mild cognitive impairment

Last post by NHE « Sat Apr 10, 2021 3:22 pm
Posted in Natural Approach

by NHE » Sat Apr 10, 2021 3:22 pm » in Natural Approach

Pilot feasibility and safety study examining the effect of medium chain triglyceride supplementation in subjects with mild cognitive impairment: A...

0 Replies

64 Views

Last post by NHE
Sat Apr 10, 2021 3:22 pm
IndeeLift

Last post by NHE « Thu Apr 08, 2021 11:47 am
Posted in Medical Devices

by NHE » Thu Apr 08, 2021 11:47 am » in Medical Devices

The IndeeLift looks like an interesting device for folks needing help getting up off the floor.

0 Replies

108 Views

Last post by NHE
Thu Apr 08, 2021 11:47 am
The WalkAide System Product # 20-1000

Last post by sk04g « Thu Apr 08, 2021 7:46 am
Posted in Medical Devices

by sk04g » Thu Apr 08, 2021 7:46 am » in Medical Devices

Selling a WalkAide System for $5500 or best offer. Unit was tried on and it didn't work out. Message me if you have any questions! :)

0 Replies

63 Views

Last post by sk04g
Thu Apr 08, 2021 7:46 am
BDNF precursor in the immune system is a novel target for treating MS

Last post by NHE « Thu Apr 08, 2021 3:18 am
Posted in General Discussion

by NHE » Thu Apr 08, 2021 3:18 am » in General Discussion

Brain-derived neurotrophic factor precursor in the immune system is a novel target for treating multiple sclerosis
Theranostics. 2021 Jan...

0 Replies

89 Views

Last post by NHE
Thu Apr 08, 2021 3:18 am
Adolescent infection increases MS risk

Last post by NHE « Thu Apr 08, 2021 3:01 am
Posted in MS Etiology and Pathogenesis

by NHE » Thu Apr 08, 2021 3:01 am » in MS Etiology and Pathogenesis

Hospital-diagnosed infections before age 20 and risk of a subsequent multiple sclerosis diagnosis
Brain. 2021 Mar 9;awab100.

The involvement of...

0 Replies

82 Views

Last post by NHE
Thu Apr 08, 2021 3:01 am
Mast cells

Last post by Petr75 « Tue Apr 06, 2021 3:58 am
Posted in General Discussion

by Petr75 » Tue Apr 06, 2021 3:58 am » in General Discussion

2021 Nov
Department of Anesthesiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China
Neuroimmune...

0 Replies

111 Views

Last post by Petr75
Tue Apr 06, 2021 3:58 am
OCT shows reduced retinal layer thickness is associated with disability progression

Last post by NHE « Thu Apr 01, 2021 5:20 pm
Posted in General Discussion

by NHE » Thu Apr 01, 2021 5:20 pm » in General Discussion

Association of Spectral-Domain OCT With Long-term Disability Worsening in Multiple Sclerosis
Neurology. 2021 Mar 2;10.1212

Objective: To evaluate...

0 Replies

115 Views

Last post by NHE
Thu Apr 01, 2021 5:20 pm
Acetyl L-Carnitine Arginate promotes nerve growth factor...

Last post by DIM « Thu Apr 01, 2021 4:01 am
Posted in General Discussion

by DIM » Thu Apr 01, 2021 4:01 am » in General Discussion

...3,5 fold more than Acetyl L-Carnitine:

(

0 Replies

136 Views

Last post by DIM
Thu Apr 01, 2021 4:01 am
Echoes

Last post by NHE « Tue Mar 30, 2021 5:57 am
Posted in Daily Life

by NHE » Tue Mar 30, 2021 5:57 am » in Daily Life

Overhead the albatross hangs motionless upon the air
And deep beneath the rolling waves in labyrinths of coral caves
The echo of a distant time comes...

0 Replies

170 Views

Last post by NHE
Tue Mar 30, 2021 5:57 am
Behçet's Disease Is Associated with MS and Rheumatoid Arthritis

Last post by Petr75 « Wed Mar 24, 2021 10:39 am
Posted in General Discussion

by Petr75 » Wed Mar 24, 2021 10:39 am » in General Discussion

2021 Mar 23
Department of Biomedicine and Health Science, Graduate School, The Catholic University of Korea, Seoul, Republic of Korea
Behçet's...

0 Replies

161 Views

Last post by Petr75
Wed Mar 24, 2021 10:39 am
MnTBAP

Last post by Petr75 « Wed Mar 24, 2021 8:32 am
Posted in General Discussion

by Petr75 » Wed Mar 24, 2021 8:32 am » in General Discussion

2021 Mar 8
Department of Neurology & Neurotherapeutics, University of Texas Southwestern Medical School, Dallas, TX, USA
The antioxidant MnTBAP does...

0 Replies

147 Views

Last post by Petr75
Wed Mar 24, 2021 8:32 am
Acyclovir/Valacyclovir long term use

Last post by DIM « Mon Mar 22, 2021 6:41 am
Posted in General Medications

by DIM » Mon Mar 22, 2021 6:41 am » in General Medications

For those that take one of the above antivirals for their MS could you post please:

-for how long you take it
-what, if any, side effects you...

0 Replies

224 Views

Last post by DIM
Mon Mar 22, 2021 6:41 am
Autonomic Dysfunction in MS: Exercise Implications

Last post by jimmylegs « Fri Mar 19, 2021 1:22 pm
Posted in Exercise and Physical Therapy

by jimmylegs » Fri Mar 19, 2021 1:22 pm » in Exercise and Physical Therapy

Autonomic Dysfunction in Multiple Sclerosis: Implications for Exercise (2014)

... Conclusion
Compounding evidence now indicates that regular...

0 Replies

127 Views

Last post by jimmylegs
Fri Mar 19, 2021 1:22 pm
Dopamine

Last post by Petr75 « Thu Mar 18, 2021 4:06 am
Posted in General Discussion

by Petr75 » Thu Mar 18, 2021 4:06 am » in General Discussion

2021
Federal Center of Brain Research and Neurotechnology, Moscow, Russia
The prospect of dopaminergic therapy in multiple sclerosis

Abstract...

0 Replies

166 Views

Last post by Petr75
Thu Mar 18, 2021 4:06 am
Ocrevus vs. Kesimpta

Last post by NHE « Wed Mar 17, 2021 8:16 pm
Posted in Ocrevus (Ocrelizumab)

by NHE » Wed Mar 17, 2021 8:16 pm » in Ocrevus (Ocrelizumab)

Ocrevus and Kesimpta are two different anti-CD20 antibodies which induce B-cell depletion. Dr. Brandon Beaber presents an interesting comparison of...

0 Replies

161 Views

Last post by NHE
Wed Mar 17, 2021 8:16 pm
Blood Trace Element Status in pwMS

Last post by jimmylegs « Wed Mar 17, 2021 9:01 am
Posted in Natural Approach

by jimmylegs » Wed Mar 17, 2021 9:01 am » in Natural Approach

Blood Trace Element Status in Multiple Sclerosis: a Systematic Review and Meta-analysis (2021)

This meta-analysis revealed that the circulating...

0 Replies

147 Views

Last post by jimmylegs
Wed Mar 17, 2021 9:01 am
Telmisartan

Last post by Petr75 « Wed Mar 17, 2021 4:08 am
Posted in General Discussion

by Petr75 » Wed Mar 17, 2021 4:08 am » in General Discussion

2021 Mar 11
Center of Excellence, Arab Academy for Science and Technology and Maritime Transport, Alexandria, Egypt
Neuroprotective Effects of...

0 Replies

160 Views

Last post by Petr75
Wed Mar 17, 2021 4:08 am
QSM-MRI can show brain inflammation.

Last post by frodo « Tue Mar 16, 2021 10:55 am
Posted in MS Etiology and Pathogenesis

by frodo » Tue Mar 16, 2021 10:55 am » in MS Etiology and Pathogenesis

QSM-MRI can show brain inflammation. Currently there is none.

QSM is an imaging biomarker for chronic glial activation inmultiple sclerosis lesions...

0 Replies

148 Views

Last post by frodo
Tue Mar 16, 2021 10:55 am
the funny snow man

Last post by zen2010 « Sun Mar 14, 2021 11:48 am
Posted in Humor

by zen2010 » Sun Mar 14, 2021 11:48 am » in Humor

lol

0 Replies

276 Views

Last post by zen2010
Sun Mar 14, 2021 11:48 am
Molecular hydrogen

Last post by Petr75 « Fri Mar 12, 2021 9:55 pm
Posted in General Discussion

by Petr75 » Fri Mar 12, 2021 9:55 pm » in General Discussion

2016 May 15
Institute of Neuroscience and Key Laboratory of Molecular Neurobiology of the Ministry of Education, Second Military Medical University,...

0 Replies

191 Views

Last post by Petr75
Fri Mar 12, 2021 9:55 pm
Guggulsterone

Last post by Petr75 « Fri Mar 12, 2021 11:04 am
Posted in General Discussion

by Petr75 » Fri Mar 12, 2021 11:04 am » in General Discussion

2021 Feb 26
Neuropharmacology Division, Department of Pharmacology, ISF College of Pharmacy, India
Guggulsterone ameliorates ethidium...

0 Replies

183 Views

Last post by Petr75
Fri Mar 12, 2021 11:04 am
Biomarkers. Extensive review as of 2021

Last post by frodo « Mon Mar 08, 2021 8:32 pm
Posted in MS Etiology and Pathogenesis

by frodo » Mon Mar 08, 2021 8:32 pm » in MS Etiology and Pathogenesis

Biomarkers in Multiple sclerosis: what place for oxysterols?

The main markers of multiple sclerosis that have been identified are involved in the...

0 Replies

166 Views

Last post by frodo
Mon Mar 08, 2021 8:32 pm
MicroRNA in MS and other diseases

Last post by frodo « Mon Mar 08, 2021 8:17 pm
Posted in MS Etiology and Pathogenesis

by frodo » Mon Mar 08, 2021 8:17 pm » in MS Etiology and Pathogenesis

MiRNA dysregulation multiple sclerosis

MiRNAs dysregulation display strong association with multiple sclerosis (MS). Several MiRNAs were reported to...

0 Replies

160 Views

Last post by frodo
Mon Mar 08, 2021 8:17 pm
Teri helps recovering optic nerve

Last post by frodo « Mon Mar 08, 2021 8:02 pm
Posted in MS Etiology and Pathogenesis

by frodo » Mon Mar 08, 2021 8:02 pm » in MS Etiology and Pathogenesis

Teriflunomide treatment is associated with optic nerve recovery in early multiple sclerosis

Beneficial properties of TRF beyond pure...

0 Replies

155 Views

Last post by frodo
Mon Mar 08, 2021 8:02 pm
Frequency and characteristics of MS misdiagnosis

Last post by NHE « Sun Mar 07, 2021 9:07 pm
Posted in General Discussion

by NHE » Sun Mar 07, 2021 9:07 pm » in General Discussion

The frequency and characteristics of MS misdiagnosis in patients referred to the multiple sclerosis centre of Catalonia
Mult Scler. 2021 Feb 10...

0 Replies

214 Views

Last post by NHE
Sun Mar 07, 2021 9:07 pm
Na-R-lipoic acid is better absorbed than R-lipoic acid

Last post by NHE « Sat Mar 06, 2021 4:12 am
Posted in Natural Approach

by NHE » Sat Mar 06, 2021 4:12 am » in Natural Approach

The sodium salt of r-lipoic acid is better absorbed than regular r-lipoic acid (which is unstable and easily polymerizes).

The plasma...

0 Replies

159 Views

Last post by NHE
Sat Mar 06, 2021 4:12 am
BNN20

Last post by Petr75 « Tue Mar 02, 2021 10:05 am
Posted in General Discussion

by Petr75 » Tue Mar 02, 2021 10:05 am » in General Discussion

2021 Feb 13
Department of Basic Science, Faculty of Medicine, University of Crete, Greece
The beneficial role of the synthetic microneurotrophin...

0 Replies

184 Views

Last post by Petr75
Tue Mar 02, 2021 10:05 am
Tryptamine

Last post by Petr75 « Tue Mar 02, 2021 9:32 am
Posted in General Discussion

by Petr75 » Tue Mar 02, 2021 9:32 am » in General Discussion

2021 Jan 25
Department of Pathology, Microbiology and Immunology, University of South Carolina School of Medicine, Columbia, SC, United States...

0 Replies

198 Views

Last post by Petr75
Tue Mar 02, 2021 9:32 am
Charlotte's Web collaborates with McLean Hospital

Last post by NHE « Mon Mar 01, 2021 3:47 am
Posted in Medical Marijuana

by NHE » Mon Mar 01, 2021 3:47 am » in Medical Marijuana

Charlotte's Web's CW Labs Announce New Scientific Collaboration Researching Hemp CBD Efficacy
February 26, 2021

BOULDER, Colo., Feb. 24, 2021...

0 Replies

187 Views

Last post by NHE
Mon Mar 01, 2021 3:47 am
Enhancing quality of life in PMS with powered robotic exoskeleton

Last post by NHE « Sun Feb 28, 2021 1:14 am
Posted in Exercise and Physical Therapy

by NHE » Sun Feb 28, 2021 1:14 am » in Exercise and Physical Therapy

Enhancing quality of life in progressive multiple sclerosis with powered robotic exoskeleton
Mult Scler. 2021 Mar;27(3):483-487.

Wearable powered...

0 Replies

168 Views

Last post by NHE
Sun Feb 28, 2021 1:14 am
MS Associated B Cells in CSF

Last post by NHE « Fri Feb 26, 2021 8:16 am
Posted in General Discussion

by NHE » Fri Feb 26, 2021 8:16 am » in General Discussion

Mass Cytometry of CSF Identifies an MS-Associated B-cell Population
Neuroimmunology & Neuroinflammation March 2021; 8 (2)

Objective: To identify...

0 Replies

248 Views

Last post by NHE
Fri Feb 26, 2021 8:16 am
TNF demyelination considered as MS

Last post by frodo « Wed Feb 24, 2021 2:05 am
Posted in MS Etiology and Pathogenesis

by frodo » Wed Feb 24, 2021 2:05 am » in MS Etiology and Pathogenesis

TNF-α blockers-associated multiple sclerosis

Conclusion

Our study confirmed that the exposure to TNFα blockers can be associated to a broad...

0 Replies

208 Views

Last post by frodo
Wed Feb 24, 2021 2:05 am
α1-3Gal

Last post by Petr75 « Tue Feb 23, 2021 12:11 am
Posted in General Discussion

by Petr75 » Tue Feb 23, 2021 12:11 am » in General Discussion

2021 Feb 5
Centre de Recherche en Transplantation et Immunologie UMR 1064, INSERM, Université de Nantes, Nantes, France; Institut de Transplantation...

0 Replies

219 Views

Last post by Petr75
Tue Feb 23, 2021 12:11 am
Audiovestibular

Last post by Petr75 « Mon Feb 22, 2021 12:54 pm
Posted in General Discussion

by Petr75 » Mon Feb 22, 2021 12:54 pm » in General Discussion

2021 Feb 5
Department of Speech and Hearing, School of Clinical Therapies, College of Medicine and Health, University College Cork, Cork, Ireland...

0 Replies

282 Views

Last post by Petr75
Mon Feb 22, 2021 12:54 pm
Sleep is your superpower

Last post by NHE « Sat Feb 20, 2021 12:22 am
Posted in Daily Life

by NHE » Sat Feb 20, 2021 12:22 am » in Daily Life

TED Talk: Sleep is Your Superpower - Matthew Walker, UC Berkeley

0 Replies

190 Views

Last post by NHE
Sat Feb 20, 2021 12:22 am
Physical activity improves brain health

Last post by NHE « Thu Feb 18, 2021 2:36 am
Posted in Exercise and Physical Therapy

by NHE » Thu Feb 18, 2021 2:36 am » in Exercise and Physical Therapy

Prospective Analysis of Leisure-Time Physical Activity in Midlife and Beyond and Brain Damage on MRI in Older Adults
Neurology. 2021 Feb...

0 Replies

184 Views

Last post by NHE
Thu Feb 18, 2021 2:36 am
Visual evoked potentials facilitate MS diagnosis

Last post by NHE « Thu Feb 18, 2021 2:19 am
Posted in General Discussion

by NHE » Thu Feb 18, 2021 2:19 am » in General Discussion

Optic Nerve Topography in Multiple Sclerosis Diagnosis: The Utility of Visual Evoked Potentials
Neurology. 2021 Jan 26;96(4):e482-e490....

0 Replies

217 Views

Last post by NHE
Thu Feb 18, 2021 2:19 am
TREM2

Last post by Petr75 « Mon Feb 15, 2021 1:21 pm
Posted in General Discussion

by Petr75 » Mon Feb 15, 2021 1:21 pm » in General Discussion

2021 Jan 27
Skylar J Ferrara, Priya Chaudhary,
TREM2 is thyroid hormone regulated making the TREM2 pathway druggable with ligands for thyroid...

0 Replies

205 Views

Last post by Petr75
Mon Feb 15, 2021 1:21 pm
COVID Vaccine and MS

Last post by David1949 « Sun Feb 14, 2021 10:16 am
Posted in General Discussion

by David1949 » Sun Feb 14, 2021 10:16 am » in General Discussion

According to the National MS society's website people with MS should get the COVID vaccine . Although there are a few noteworthy comments.

Source...

0 Replies

527 Views

Last post by David1949
Sun Feb 14, 2021 10:16 am

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