Search found 5138 matches

by NHE
Thu Apr 28, 2005 12:56 am
Forum: Avonex
Topic: Avonex
Replies: 4
Views: 4252

Re: Avonex

You may wish to consult with your neurologist. There could be medications that can help with your shooting pains. As far as your question on whether or not you should switch from Avonex to another medication, I can't answer that directly. However, people on interferon-beta sometimes develop neutrali...
by NHE
Thu Apr 28, 2005 12:41 am
Forum: General Discussion
Topic: Question in pregnant period
Replies: 6
Views: 2308

Re: Question in pregnant period

I have a question in mind from long time ago, how is possible to a pregnant woman recover (during this period) most of her problems caused by MS if these problems are derived by a destruction in the myelin sheet? It has no big sense; if there is a hole, there is and how could it disappear? Is the s...
by NHE
Tue Apr 19, 2005 8:43 am
Forum: Avonex
Topic: Bruising While Injecting with Avonex
Replies: 4
Views: 3729

Re: Bruising While Injecting with Avonex

I occasionally get bruises, but these have only been small bruises about the size of a nickel to a quarter. In 4+ years of using Avonex, I've only hit a vein once. This was obvious when I pulled back on the syringe as there was no resistance and blood immediately entered the syringe. Do you always c...
by NHE
Wed Apr 13, 2005 6:53 pm
Forum: Reading Nook
Topic: The truth about the drug companies, Marcia Angell
Replies: 4
Views: 5244

The truth about the drug companies, Marcia Angell

I just finished reading The Truth About The Drug Companies, How They Deceive Us And What To Do About It by Marcia Angell, M.D. After reading this book I felt that it was important for me to share my impressions of it with the MS community here at ThisIsMS. I feel quite strongly that it should be req...
by NHE
Wed Apr 13, 2005 4:50 pm
Forum: General Discussion
Topic: Regular Aerobic workout improves MS?
Replies: 6
Views: 3216

Re: Regular Aerobic workout improves MS?

Several years ago I attended a seminar given by Fred H. Gage of the Salk Institute . He discussed that mice given a running wheel in their cage and allowed to freely exercise had a greater number of stem cells produced in the brain than mice which did not have the running wheel available. He also st...
by NHE
Wed Apr 06, 2005 2:06 am
Forum: Statins
Topic: Statin activity in treating MS
Replies: 8
Views: 9614

Statin activity in treating MS

This paper from the journal Nature may be old news (it's from 2002). However, I just ran across it and I thought that I would post the abstract here since it discusses some of the actions of statins that explain their efficacy in treating MS. The HMG-CoA reductase inhibitor, atorvastatin, promotes a...
by NHE
Wed Apr 06, 2005 1:50 am
Forum: General Discussion
Topic: How different is ms from other cns diseases?
Replies: 8
Views: 2904

Re: How different is ms from other cns diseases?

Wesley, I don't know if this will answer your question but I thought it might be helpful. While this is just one paper, these authors state that epitope spreading is not necessary for the development of EAE. I should note that this paper is freely available from the Journal of Immunology. If this do...
by NHE
Tue Apr 05, 2005 1:12 am
Forum: General Discussion
Topic: MS and Benzene Exposure
Replies: 13
Views: 4195

Re: MS and Benzene Exposure

In looking up the Safety Data Sheet on this particular detergent I find that it containes Benzene As others have pointed out, benzene is a known carcinogen. I would treat it with the respect it deserves, e.g., only use it in a fume hood, wear gloves, and where necessary use a respirator. It might a...
by NHE
Tue Apr 05, 2005 12:40 am
Forum: General Discussion
Topic: How different is ms from other cns diseases?
Replies: 8
Views: 2904

Re: How different is ms from other cns diseases?

What is the basis for the assumption that ms involves the immune system or is an auto-immune disease? To the best of my understanding, adoptive transfer plays a big role in the autoimmune theory of MS. Essentially, activated T cells which target proteins such as myelin oligodendroycte glycoprotein ...
by NHE
Sun Mar 20, 2005 12:52 am
Forum: General Discussion
Topic: Good news - Major milestone in identifying ms genes
Replies: 28
Views: 5456

Re: Quoting authors

bromley wrote:OddDuck wrote: (I can't work out the quote option)
That would be
author wrote: followed by the end quote.

NHE
by NHE
Fri Mar 18, 2005 4:04 am
Forum: General Discussion
Topic: Good news - Major milestone in identifying ms genes
Replies: 28
Views: 5456

Re: Good news - Major milestone in identifying ms genes

Would be grateful if those with the relevant knowledge could translate into what this might mean Researchers at SGI used the Affymetrix GeneChip technology to scan over 100,000 SNPs (single nucleotide polymorphisms) to identify the genes involved in MS, comparing the genetic profile of cases and co...
by NHE
Fri Mar 18, 2005 2:39 am
Forum: General Discussion
Topic: Will the last ms researcher turn out the lights
Replies: 19
Views: 5362

Re: Will the last ms researcher turn out the lights

Arron wrote:it's on the front page :idea:
Thanks Arron. It seems that lately I could use a few more :idea: !

NHE
by NHE
Wed Mar 16, 2005 4:05 pm
Forum: General Discussion
Topic: Will the last ms researcher turn out the lights
Replies: 19
Views: 5362

Re: Will the last ms researcher turn out the lights

bromely wrote:PS - just seen the news on Avonex and liver failure. Why don't we do something radical today - bust Biogen.
It would be great if you could post a link to this news article.

Thanks, NHE
by NHE
Sun Mar 13, 2005 7:10 pm
Forum: General Discussion
Topic: Needle-less injection, why hasn't this been looked at?
Replies: 17
Views: 6650

Re: Needleless injection

Site reactions are probably one of the most prevalent problems with interferons. Not with all interferons. I use Avonex which is administered via an IM injection. After a little over four years of using Avonex, the only injection site reaction that I've experienced is that on rare occasions I might...
by NHE
Sun Mar 13, 2005 5:02 am
Forum: Tysabri (Antegren or Natalizumab)
Topic: Tysabri Suspension - after shocks will be?
Replies: 60
Views: 14882

Re: Tysabri Suspension - after shocks will be?

Guess what? There have been many, many deaths in the Tysabri trials. Things like bike accidents and sepsis and suicide. Things that clearly have *nothing* at all to do with Tysabri. Perhaps I'm confused about this but it seems to me that sepsis could very well be directly related to Tysabri since i...