Search found 190 matches

by DrGeoff
Sun Apr 03, 2016 1:56 pm
Forum: General Discussion
Topic: Why should I take DMDs? Not being rhetorical (x-post MSWorld
Replies: 16
Views: 1784

Re: Why should I take DMDs? Not being rhetorical (x-post MSW

When I was offered a DMD (my choice, interferon or Copaxone) I dithered for six months.
In those six months I had three relapses.
I wish I had started (Copaxone) immediately.
Geoff
by DrGeoff
Thu Feb 11, 2016 10:27 am
Forum: General Discussion
Topic: Remission of Severe Myasthenia Gravis After Massive-Dose D
Replies: 10
Views: 1738

Re: Remission of Severe Myasthenia Gravis After Massive-Dose

If you want to label something ad hominem it might be a good idea to read the argument in the relevant post (what argument?). The post from tedhutchinson contained a diatribe against the medical profession. Since the standard definition of an argument is A logical progression of thought , it can be ...
by DrGeoff
Sat Feb 06, 2016 9:50 am
Forum: General Discussion
Topic: Remission of Severe Myasthenia Gravis After Massive-Dose D
Replies: 10
Views: 1738

Re: Remission of Severe Myasthenia Gravis After Massive-Dose

cureorbust wrote: " ... and is also from a Journal which commenced in Nov 2015. ie not a publication held highly by the established medical fraternity ... And that is not the whole story. The American Journal of Case Reports is an offshoot of a respectable set of publications that do an indexing se...
by DrGeoff
Thu Jan 28, 2016 4:42 am
Forum: General Discussion
Topic: Question Regarding Drop Foot
Replies: 16
Views: 2437

Re: Question Regarding Drop Foot

Hi Isaac, Drop foot can be an early sign of MS, or it can develop after the diagnosis. In simple terms, as the heel on the affected foot leaves the ground, the ball of that foot (and hence the toes) do not. tHey drag, they catch, and you need some way to keep your balance. OK, so you swing your foot...
by DrGeoff
Wed Jan 13, 2016 11:13 am
Forum: General Discussion
Topic: Measuring MS
Replies: 24
Views: 2335

Re: Measuring MS

The paper cited by cheer did suggest this.
The correlations are not overwhelming, but that could be down to a problem with the measures of disability that were referenced.
Geoff
by DrGeoff
Wed Jan 13, 2016 6:33 am
Forum: General Discussion
Topic: Measuring MS
Replies: 24
Views: 2335

Re: Measuring MS

http://www.smw.ch/content/smw-2013-13887/ Well, what a can of worms this has opened - but I doubt if the right people will look at the worms and go away for a rethink. Measuring brain atrophy (whether en masse , or by specific lobes or areas) seems so easy, one has to wonder why no-one else has thou...
by DrGeoff
Thu Jan 07, 2016 2:33 pm
Forum: Biotin (Qizenday, Cerenday, MD1003)
Topic: How are you doing on biotin?
Replies: 12
Views: 4485

Re: How are you doing on biotin?

High dose Biotin for about 5 months, dissolved in water.
Small improvements that are not likely to be due to anything else.
Starting point was EDSS 6.5
Read about it on http://gnh1.blogspot.co.uk/
Geoff
by DrGeoff
Thu Dec 31, 2015 3:47 am
Forum: General Discussion
Topic: Symptoms?
Replies: 3
Views: 768

Re: Symptoms?

And please do not forget a check for Vit B12 deficiency - the symptoms of this can mimic MS.
Geoff
by DrGeoff
Sat Dec 26, 2015 1:43 pm
Forum: Biotin (Qizenday, Cerenday, MD1003)
Topic: MEDDAY'S MD1003 STUDY FAILS TO REACH PRIMARY ENDPOINT
Replies: 4
Views: 2905

Re: MEDDAY'S MD1003 STUDY FAILS TO REACH PRIMARY ENDPOINT

Can we conclude then that MD1003 is another dud? And what happened to the first study that showed positive results? If you conclude that, David, then you have failed to read the other posts in this thread. The latest MD1003 trial was directed specifically at Trigeminal Neuralgia. Far from being a d...
by DrGeoff
Sat Dec 26, 2015 1:27 pm
Forum: General Discussion
Topic: Trigeminal neuralgia
Replies: 1
Views: 834

Re: Trigeminal neuralgia

I doubt if your headaches have anything to do with Trigeminal neuralgia. The Trigeminal nerve has three branches - Optic nerve and two others. One along the lower jaw, and the other across from nose to cheekbone. Any of these can be painful in the extreme, to the extent that (for example) an air cur...
by DrGeoff
Tue Dec 22, 2015 3:23 pm
Forum: Biotin (Qizenday, Cerenday, MD1003)
Topic: MEDDAY'S MD1003 STUDY FAILS TO REACH PRIMARY ENDPOINT
Replies: 4
Views: 2905

Re: MEDDAY'S MD1003 STUDY FAILS TO REACH PRIMARY ENDPOINT

And do please note that this study was directed at Optical Neuritis in progressive and relapsing forms. And, like COB points out, the MD1003 worked - but not quite enough to meet statistical significance. Also, consider what this tells us about MedDay - they are not attempting to massage the figures...
by DrGeoff
Thu Dec 17, 2015 2:04 pm
Forum: Biotin (Qizenday, Cerenday, MD1003)
Topic: The biotin trial results are out
Replies: 121
Views: 28018

Re: The biotin trial results are out

This is a followup to my post of Nov 16. Since then: I stopped Biotin 4 days before a blood draw for the PSA test and stayed off for another few days before a Urology appointment. I have just had the copy report to my General Practitioner. The PSA level had dropped to normal for age, and there was n...
by DrGeoff
Tue Dec 15, 2015 3:02 pm
Forum: Biotin (Qizenday, Cerenday, MD1003)
Topic: which biotin?
Replies: 19
Views: 7803

Re: which biotin?

When I looked into this a few months back, I found that there was claimed to be only one manufacturer of Biotin in Europe - and no, it is not Alfa who are Chinese. The Chinese producers generally consider anything better than 97.5% pure to be "pure", so you pay up and take your choice. I imagine tha...
by DrGeoff
Fri Dec 11, 2015 9:06 am
Forum: General Discussion
Topic: Question for those in the UK
Replies: 3
Views: 673

Re: Question for those in the UK

Hi Jaded Unless you are elderly, just about any GP should be able to prescribe it. There is a warning in the BNF about possible neurological complications with the old - so a GP might want to monitor someone with MS. Probably best to start with a good pharmacist who should be able to quantify the ri...
by DrGeoff
Fri Dec 11, 2015 8:53 am
Forum: General Discussion
Topic: Transverse myelitis - anyone?
Replies: 10
Views: 3923

Re: Transverse myelitis - anyone?

I started with TIM (I being "inflammatory"). Toes went numb. Numbness spread up my body as far as my armpits. GP said "See a Neuro fast!" Went private (the British NHS does not do "fast"). The numbness faded, but an MRI showed spinal lesion T5-T6. Neuro referred me to himself in the NHS and then a r...