Search found 252 matches

by BioDocFL
Wed Jul 23, 2008 4:59 pm
Forum: General Discussion
Topic: show broadcast about MS
Replies: 6
Views: 2853

I haven't seen it mentioned on ThisIsMS.org but I heard that Michelle Obama's father had MS. Perhaps if she becomes First Lady, she will become an advocate for more MS research.

Wesley
by BioDocFL
Tue Jul 15, 2008 3:53 pm
Forum: Natural Approach
Topic: all things vitamin D
Replies: 1115
Views: 232116

Vitamin D deficiency is becoming a concern. Article in USAToday.

'Vitamin D tests soar as deficiency, diseases linked'

http://www.usatoday.com/news/health/200 ... ests_N.htm
by BioDocFL
Sun Jun 22, 2008 6:27 pm
Forum: General Discussion
Topic: MS?
Replies: 4
Views: 2695

Sherry, While you're waiting to hear back from the doctor, you could be doing some things in the mean time. There may be more than one thing going on here: thyroid problem, drug-interactions, possible MS, allergy or reaction to something. It could be a combination so see what you can eliminate: 1) C...
by BioDocFL
Sun May 25, 2008 8:26 am
Forum: General Discussion
Topic: Computer-based molecular modeling in drug discovery
Replies: 4
Views: 4372

Computer-based molecular modeling in drug discovery

Computer modeling in drug discovery I have been asked to comment on a treatment protocol being put forward based on computer modeling of small molecules in the ligand binding sites of receptors. I am not familiar with the protocol but I can comment on some of the many caveats that must be considered...
by BioDocFL
Tue May 13, 2008 7:22 pm
Forum: General Discussion
Topic: Experience Project
Replies: 5
Views: 3314

Way to go Aaron!

D.E. Shaw is an investor in the Schrodinger L.L.C. company (New York and Portland) that makes the molecular modeling software that we use in our drug discovery work. A class act all the way around. It's easy to see the connections now, i.e. quality finds quality.

Wesley
by BioDocFL
Wed Apr 30, 2008 9:04 am
Forum: General Discussion
Topic: new here - scared, lonely, and depressed.
Replies: 46
Views: 10257

SallyDC,

You said you moved into a new apartment. Could there be anything toxic around that, like mold? It can give some bad symptoms. Possibly an inspector can check around for you. It's something you can do while you are waiting for a diagnosis regarding any MS.

Wesley
by BioDocFL
Mon Apr 07, 2008 10:19 am
Forum: General Discussion
Topic: Epigenetics
Replies: 21
Views: 8242

Dignan, I am in San Diego this week for the FASEB meeting (Federation of American Societies of Experimental Biology). I happened to hear a talk yesterday morning by Dr. Claudia Lucchinetti on the patterns of MS and she went on about some other demyelinating diseases. Hers was a special TEVA/Parisi a...
by BioDocFL
Sat Mar 29, 2008 6:48 am
Forum: General Discussion
Topic: Another target
Replies: 4
Views: 2149

So does this make MS a connective tissue disease? Lupus is referred to as a connective tissue disease so they are sharing more and more similarities. Hmmmm? Interesting I think.

Wesley
by BioDocFL
Sun Mar 23, 2008 1:50 pm
Forum: General Discussion
Topic: Your wildest imagination
Replies: 28
Views: 6519

Cooties are imaginary bugs or germs. Little boys say girls have cooties when they are going through that girl-hating stage, and the little girls will say boys have cooties when they are going through their boy-hating stage. When they get to adolescence, they seem to forgot about cooties and start ch...
by BioDocFL
Sat Mar 22, 2008 4:16 pm
Forum: General Discussion
Topic: Your wildest imagination
Replies: 28
Views: 6519

Marcstck, I was diagnosed by classmates early in kindergarten as having cooties, along with severe stinkiness, but it never developed into anything more. I have almost outgrown both. Seriously though, there is a new article out in Nature Neuroscience suggesting that MS plaques (via proteomic analysi...
by BioDocFL
Sat Mar 15, 2008 7:01 am
Forum: General Discussion
Topic: Anaylsis of the American MS Market
Replies: 3
Views: 2522

http://abcnews.go.com/Health/GadgetGuide/Story?id=4455227&page=4 Not specifically mentioning MS but the article below is about diseases in general. It shows where a lot of research is heading: towards personalized medicine. It is interesting to note that they are calling diabetes potentially 12 ...
by BioDocFL
Fri Mar 07, 2008 7:05 am
Forum: General Discussion
Topic: Human endogenous retroviruses again
Replies: 4
Views: 2180

It was a good bit of detail. At least I didn't write it in Latin (since I don't know Latin). It is complicated stuff but I have been seeing patterns in it. Alu sequences are about 80-410 bases long. This is similar length to the DNA framentation seen in apoptosis, so I am thinking some of what is in...
by BioDocFL
Thu Mar 06, 2008 9:14 pm
Forum: General Discussion
Topic: Human endogenous retroviruses again
Replies: 4
Views: 2180

There are ~50,000 LINE1 sequences throughout the human genome. LINE1 sequences originate from reverse transcriptases from retroviruses. An estimated 60 of the copies code for fully functional reverse transcriptases. So, if in a heat shock response, one of the functional LINE sequences gets transcrib...
by BioDocFL
Sun Feb 17, 2008 3:20 pm
Forum: General Discussion
Topic: MS Protein research
Replies: 3
Views: 2260

I am wondering if this Lawrence Steinman is related to Charles Steinman. I am guessing that Lawrence Steinman is Charles' son. A lot of nepotism in science, but no big deal. Charles Steinman had some interesting findings back in the 70's & 80's related to lupus. I think Charles Steinman's findin...
by BioDocFL
Sat Feb 09, 2008 6:37 pm
Forum: General Discussion
Topic: The pork thing
Replies: 8
Views: 3229

Bob, I see your point. A need to resolve the mystery. Solve the case in 30 minutes and then roll the credits. I've been interested in autoimmune diseases for 30 years without the resolution but if I was paying for it as a cable TV subscription, I would want to at least have the Cartoon Network and E...

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