Search found 1612 matches

by dignan
Sat Oct 02, 2010 12:01 pm
Forum: General Discussion
Topic: omes
Replies: 0
Views: 1464

omes

Here is some recent news about the human proteome project and the human connectome project. I think progress on these projects can't hurt our understanding of MS. Proteome: http://www.lifescientist.com.au/article/361934/human_proteome_project_launches_sydney/?fp=4194304&fpid=1 http://www.lifesci...
by dignan
Wed Sep 22, 2010 8:09 am
Forum: Drug Pipeline
Topic: Summary of the pipeline
Replies: 437
Views: 219738

Based on this post from gkalman, I added gilenya to the approved list:

http://www.thisisms.com/ftopict-13876.html

I think we are going to see new MS drug approvals every year from now on (until a cure).
by dignan
Sat Sep 18, 2010 5:29 pm
Forum: Drug Pipeline
Topic: Summary of the pipeline
Replies: 437
Views: 219738

Thanks NHE, don't know what happened to that link. Daisy, yep, it's a drag. Actually, anything that's still in phase 2, even if it has been in phase 2 trials for a couple of years, is AT LEAST 4 years from approval, and 5 or 6 years is more realistic, and 8 years isn't unreasonable. Clinical trials ...
by dignan
Sat Sep 18, 2010 8:46 am
Forum: Drug Pipeline
Topic: Summary of the pipeline
Replies: 437
Views: 219738

Based on a posting from squiffy2 I added MIS416 to the phase 2 list. I like it because it's for progressive MS and Innate Therapeutics got some funding from Fast Forward:

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by dignan
Wed Sep 15, 2010 12:11 pm
Forum: General Discussion
Topic: Small study shows Asthma drug improves MS outcomes
Replies: 5
Views: 2444

This is a continuation of a study reported on back in 2009:

http://www.thisisms.com/ftopicp-52248-a ... html#52248

It does look like taking albuterol for the first year of being on copaxone leads to better outcomes.
by dignan
Sat Sep 11, 2010 9:24 am
Forum: General Discussion
Topic: ECTRIMS 2009
Replies: 17
Views: 5712

More Aussie research on astrocytes: Mult Scler. 2010 Sep 7. [Epub ahead of print] Neuromyelitis optica: a demyelinating disease characterized by acute destruction and regeneration of perivascular astrocytes. Parratt JD, Prineas JW. The Institute of Clinical Neurosciences, Department of Medicine, The...
by dignan
Thu Aug 26, 2010 12:32 pm
Forum: Drug Pipeline
Topic: Summary of the pipeline
Replies: 437
Views: 219738

ssrn00, there is a "Natural Approach" forum that might be appropriate for your experience. If you're not sure about the rules of the board, they can be found here: http://www.thisisms.com/ftopict-39.html
by dignan
Mon Aug 23, 2010 9:16 pm
Forum: General Discussion
Topic: autologous stem cell transplant
Replies: 21
Views: 4822

I'm with patientx, maybe check out the Cleveland Clinic trial. All the other stem cell trials in the US appear not to be recruiting patients right now (other than Northwestern). It's only a phase 1 trial, but that means there is no placebo to worry about. http://www.clinicaltrials.gov/ct2/show/NCT00...
by dignan
Sat Jul 17, 2010 10:15 am
Forum: General Discussion
Topic: International Interactome Initiative
Replies: 1
Views: 1683

Not the same initiative, but related research. It's no wonder we haven't been able to figure out diseases like MS when we don't even know all of the different proteins that could potentially be involved. Thousands of New Proteins Discovered in Spinal Fluid July 16, 2010 -- PhysOrg.com -- Scientists ...
by dignan
Sat Jul 17, 2010 7:54 am
Forum: Rebif
Topic: ok-rebif?? that's is
Replies: 8
Views: 4008

Same for me: don't like it but am satisfied with my choice as I've had no relapses and have no side effects after over 6 years on the drug.
by dignan
Thu Jul 08, 2010 11:47 am
Forum: General Discussion
Topic: International Interactome Initiative
Replies: 1
Views: 1683

International Interactome Initiative

It's hard to imagine getting to the bottom of any complex, as yet not understood disease, like MS, without knowing all the proteins involved and how they interact. Human genome: the hunt continues for 'malicious proteins' July 8, 2010 -- Scientific advances of the past decade have shed new light on ...
by dignan
Wed Jul 07, 2010 8:43 pm
Forum: General Discussion
Topic: For those who associate MS with a virus
Replies: 26
Views: 5811

I don't know about kids these days, but nice article Bob. Sounds like GeNeuro is an interesting company to watch: http://www.geneuro.com/
by dignan
Sun Jul 04, 2010 8:33 am
Forum: Stem Cells
Topic: The Second Huge Stem Cell Breakthrough in a Week
Replies: 10
Views: 3684

gothicrosie, there are a few trials of mesenchymal stem cells in people with MS that don't involve wiping out the immune system. Here are some links: -- http://www.clinicaltrials.gov/ct2/show/NCT00813969 -- http://www.clinicaltrials.gov/ct/show/NCT00395200 -- http://www.clinicaltrials.gov/ct2/show/N...
by dignan
Wed Jun 30, 2010 7:12 am
Forum: Daily Life
Topic: $tre$$
Replies: 27
Views: 6933

jimmy, I'm sorry to hear about your job, and your home. This economy blows, but maybe all those smug economics commentators will be right about Canada's economy being in relatively good shape and you'll find a new job fast.
by dignan
Mon Jun 28, 2010 1:59 pm
Forum: General Discussion
Topic: Intrathecal methotrexate shows promising results
Replies: 6
Views: 2712

Daisy3, in case you want to know some first hand experiences, marcstck and bestadmom have both had this treatment (maybe others?).

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