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Antegren doesn't even do a THING for anything else. It ONLY has ONE mechanism of action. It ONLY blocks VLA-4 (well, correction, alpha 4 beta 1, which is VLA-4, and alpha 4 beta 7), which in turn disallows T cells to cross the BBB. It doesn't stop anything else from crossing. JUST T cells. And the o...

The NAb issue is still very controversial. In the Evidence study, that you reference below, the NAb rate for Rebif was much higher than Avonex. However, the patients on Rebif that were NAb positive still did better than patients on Avonex. I think what that shows is that NAbs may reduce efficacy in ...

Good point, and since he is an investor in Elan....he has a vested interest in putting out "the good word". You sound like a rep for the company...Ive read this same info on the drug rep sites. It all sounds great, but let's face it, Biogen is great at spin- doctors know it, we know it! Fo...

Wait a minute guys....dont be so quick to think so negatively about drug company intentions. This study (ETOMS) was done a long time ago, before there was proof of a dose-response with interferons (before PRISMS). This author is simply doing a analysis of brain atrophy on those patients. The origina...

I dont have a link but the study is called the Evidence study and was required by the FDA to show that Rebif is more effective than Avonex. It also showed less flu-like symptoms, less depression, and less fatigue. There were more injection site reactions with Rebif because it is sub-q. Thats ok with...