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The right bacteria would prevent the wrong bacteria from getting a foothold (proper gut flora). Antibiotics can wreak havoc with our gut, hence the migration towards such treatments as fecal transplants and "poop pills."

From the article, it appears a probiotic would be the cure. Also, the article mentions that animals infected with this bacteria appear to suffer the MS like symptoms when fed a carbohydrate-rich diet. Perhaps, for humans infected with the same bug, a high-carb diet is also a bad idea.

Do it naturally. Zinc suppresses Th17 development via inhibition of STAT3 activation. We have shown that Zn suppressed CIA development, decreased serum levels of IL-17A, but not those of IFN-γ, and reduced the numbers of Th17 cells, but not those of Th1 cells, in regional lymph nodes. Importantly, I...

A couple of articles detailing calcitriol's effect on production of TNF-alpha: Calcitriol inhibits TNF-alpha-induced inflammatory cytokines in human trophoblasts. These data show that calcitriol prevents TNF-alpha induction of inflammatory cytokines through a process likely to be mediated by the vit...

My son suggested the same. Thanks.

Anybody else getting malware warnings from Google Chrome? Started with a post from squiffy2.

Squeakycat: Just perused a very interesting article tying Lyme (Borrelia burgdorferi), Epstein-Barre virus (EBV), some cancers, calcitriol, and VDR's together. I intend to read it more in depth, but at first blush it appears to suggest that MS has etiologies with geneses in Lyme, EBV, Cpn, and perha...

Continuing with the B12 connection (note that initial vitamin B12 level was normal): Sub-acute combined degeneration with an initially normal level of vitamin B12: a case report Abstract Introduction The neurological manifestation of vitamin B12 deficiency can occur as a result of peripheral nerve p...

I also doubt it is the only cause; in fact, I believe EBV to be the most likely culprit, either acting alone in concert with certain genetic predispositions or allying with HERV's and acting in concert with genetic predispositions. Considering that "one calcitriol dose plus vitamin D sustainabl...

Considering the etiology of "MS" is unknown, perhaps Lyme, among other diseases, is MS. Note: my son's D level at onset was below the normal range.

Squeakycat, hi: I've been following your posts on vitamin D (particularly D3 + calcitriol) and also researching it on my own on behalf of my adult son who was diagnosed with MS. In concert with my advice, his own research has led him to forego DMD's for the present (10 months, now) and self-treat wi...

From Wikipedia: Ocrelizumab targets mature B lymphocytes[1] and hence is an immunosuppressive drug candidate. It is under development by Hoffmann–La Roche's subsidiary Genentech, and Biogen Idec. It had reached Phase III clinical trials for rheumatoid arthritis[2] and lupus erythematosus, and Phase ...

They do point out that "this difference in reactivity was restricted to the CSF as serum reactivity against RBPJ did not differ between patients and controls." Perhaps another marker in the breakdown of the BBB.

I've done background research on Piping Rock as a source for supplements; they're quite inexpensive. Has anybody ever purchased from this company, and what do you think?

milesap: Very interesting. The part that caught my eye?: "However, we sorely miss the identification of normo-physiological mechanisms other than actual replication that can enhance endogenous virus expression to an extent leading to activation of the immune system. Late infection with Epstein ...