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The prevalence of MS is increasing worldwide because people and their 80 billion cells are ever less able to contain herpes viruses. https://www.thisisms.com/forum/viewtopic.php?f=1&t=31375 Besides MS, lack of herpes control causes chronic diseases such as cancers and - as a protective measure -...

The prevalence of MS is increasing worldwide because people and their 80 billion cells are ever less able to contain herpes viruses. This causes chronic diseases such as cancers and - as a protective measure - autoimmune diseases. Chronic diseases are on the rise worldwide. Cases will double by 2035...

I refer you to the other thread on the subject matter: https://www.thisisms.com/forum/viewtopic.php?f=1&t=32024 "In the past decade, there has been growing recognition that disease prevalence, course and outcomes in women and men are influenced by both biologic sex and gender. ... This FOA ...

This study grant is an interesting initiative by the NIH, but not a big surprise. I suspect the NIH is thinking in the direction of SNPs/point mutations as well, to explain the gender bias and a whole lot more. This is hopeful because I consider that if there is one organisation in the world that ca...

Chronic degenerative diseases (including MS) require a new perspective, a new contextualization and interpretation to help us challenge how we view these diseases. As these diseases are all born out of cellular action with a common underlying herpes-viral denominator, we should try to understand the...

Theoretical Immunology and Chronic Disease Part II Thinking along the Path of Evolution The thinking about our immunity started from the top. 'Top down’ approaches are dependent on the selection of known markers like T and B cell protective immunity, thus creating a bias in study design and focus. ...

Hi DIM, I decided to start slowly and used 2 x 125 mg Valacyclovir daily for 4 days. It may indeed have unleashed some sort of Herxheimer reaction that might eventually wane. But there is risk as well in continuing the experiment on my own because we don’t know what exactly happens to the delicate h...

After taking Valacyclovir for a few days, I stopped with it because of unexplained symptoms. It comes back to memory that some years ago when I also tried Valacyclovir, the same or similar symptoms were felt. In particular a deep overall fatigue, effects on the eyes and a ‘narrowed consciousness’ (s...

I think that Atara Bio's concept falls short on a number of points. First, I do not think that the B cell is the main carrier of EBV into the CNS, but that herpes strains can enter the CNS from the mucosa of the oro / naso pharynx via the Virchow Robin space. Second, I think that EBV has a much grea...

On the other thread on Ultimate outcome, expectation VS reality! (https://www.thisisms.com/forum/viewtopic.php?f=1&t=31865) we find an interesting discussion about the role of EBV in MS, and about a possible entirely new approach to stop MS progression. This is my two cents on the subject… A ren...

A renowned virologist told me that we see virtually zero cases of MS in EBV seronegative people. He argues that, if you consider that still some 5-10% of the world population is seronegative for EBV, this is a very very very strong indication that EBV is involved in MS. EBV is known as an onco virus...

Einstein said: "We cannot solve our problems with the same thinking we used when we created them". A pair of fresh eyes is badly needed. Current views in medicines need a complete overhaul or reassessment, some issues need a new horizon for thinking. And most important of all, one needs a ...

Autoimmunity: an explanatory model and questions See the figure on the uneven pages together with the text on the next page A number of key questions emerge about the workings of the immune system and the role of herpes https://drive.google.com/file/d/1IDf8zVGP5H6atWVQr3EleTpTVHbNjaHV/view?usp=sharing

This very recent article is very interesting and would seem to be fully aligned with the thinking on this thread: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691656/ Integrate it all, and we arrive at a total break-through. It is a new theory of evolution and the important role of viruses therein,...

the true value of this last study lies in the fact that it was done with a very wide group of people from all over the world. I think the interaction between brains and the rest of the body including the gut is regulated via the idiotypic regulatory network and the immune homunculus. see for instanc...