Search found 1612 matches

by dignan
Tue Apr 12, 2011 12:49 pm
Forum: General Discussion
Topic: Brain atlas
Replies: 6
Views: 3004

They have finished the human brain atlas:

http://www.physorg.com/news/2011-04-all ... -gene.html
by dignan
Tue Mar 08, 2011 6:05 pm
Forum: Drug Pipeline
Topic: Summary of the pipeline
Replies: 437
Views: 216778

I added a few things to the phase 1 and 2 lists. See here for the blow-by-blow.
by dignan
Sun Mar 06, 2011 10:19 am
Forum: Regimens
Topic: Helminthic therapy(treatment using hookworms)
Replies: 139
Views: 43448

Here is an abstract about the helminth trial in Wisconsin: Mult Scler. 2011 Mar 3. [Epub ahead of print] Probiotic helminth administration in relapsing-remitting multiple sclerosis: a phase 1 study. Fleming J, Isaak A, Lee J, Luzzio C, Carrithers M, Cook T, Field A, Boland J, Fabry Z. Department of ...
by dignan
Wed Mar 02, 2011 7:49 am
Forum: General Discussion
Topic: Scientists probe strategies to repair neuron damage in MS
Replies: 3
Views: 2206

It's not that bad Algis. A drug can get through the clinical trial process in less than 10 years. It really depends on how much money the sponsors have and how organized they are. Phase 3 trials are typically 2 years. Phase 2 trials are typically around 1 year and phase 1 trials are around 1-3 month...
by dignan
Sat Feb 05, 2011 9:20 am
Forum: Stem Cells
Topic: Research team regenerates brain tissue
Replies: 6
Views: 2293

I'll drink the kool-aid.
by dignan
Wed Feb 02, 2011 6:39 pm
Forum: Stem Cells
Topic: Research team regenerates brain tissue
Replies: 6
Views: 2293

That's really interesting, but I don't like the powdered concentrate. It doesn't have the subtle flavors and richness of the real thing...wait a minute, I forget, what are we talking about again?
by dignan
Mon Jan 31, 2011 7:01 pm
Forum: Stem Cells
Topic: now this is pretty amazing...
Replies: 5
Views: 2608

Wow.
by dignan
Thu Jan 27, 2011 8:26 pm
Forum: Drug Pipeline
Topic: S1P1
Replies: 3
Views: 2566

Thanks for the info Scorpion. I agree patientx. I don't know if that's good or bad. On the bright side, it appears to be a worthwhile target. On the other hand, is there any reason to believe this will be better than gilenya?
by dignan
Thu Jan 20, 2011 9:33 am
Forum: Rebif
Topic: Liver functions up - coming off Rebif for 2 weeks - advice?
Replies: 4
Views: 3463

Don't worry at all about taking 2-3 weeks off from Rebif. If will have either no effect, or possibly a positive effect. Mult Scler. 2000 Apr;6(2):86-90. MRI and clinical activity in MS patients after terminating treatment with interferon beta-1b. Richert ND, Zierak MC, Bash CN, Lewis BK, McFarland H...
by dignan
Sun Jan 16, 2011 5:14 pm
Forum: General Discussion
Topic: Gilenya and...Cancer??
Replies: 3
Views: 6380

The report linked below, from Novartis to the FDA, includes as much info as I've found on gilenya and cancer. The relevant section starts on page 81, it is titled "6.4.5.7 Neoplasms". Then from later in the report there is this summary: 8.2.7 Malignancy Pre-clinical data did not suggest an...
by dignan
Fri Jan 14, 2011 6:25 pm
Forum: General Discussion
Topic: One for Biodocfl
Replies: 2
Views: 1831

One for Biodocfl

A group of researchers looking into spermidine and MS / EAE. This seems right up Wesley's alley... Spermidine alleviates severity of murine experimental autoimmune encephalomyelitis. Invest Ophthalmol Vis Sci. 2011 Jan 12. [Epub ahead of print] Guo X, Harada C, Namekata K, Kimura A, Mitamura Y, Yosh...
by dignan
Wed Jan 12, 2011 12:17 pm
Forum: Diet
Topic: Coffee good or bad?
Replies: 6
Views: 3537

I think there have been other studies suggesting that caffeine has positive effects on the brain (not necessarily specific to MS), such as:

http://news.bbc.co.uk/2/hi/health/7326839.stm
by dignan
Sat Jan 08, 2011 11:44 am
Forum: Diet
Topic: caffeine
Replies: 0
Views: 2073

caffeine

An interesting abstract to browse with your coffee or tea... Impacts of methylxanthines and adenosine receptors on neurodegeneration: human and experimental studies. Handb Exp Pharmacol. 2011;200:267-310. Chen JF, Chern Y. Department of Neurology, Boston University School of Medicine, Boston, MA, US...
by dignan
Fri Dec 24, 2010 8:35 am
Forum: General Discussion
Topic: TwistedHelix doing pretty well
Replies: 7
Views: 2100

Bob, thanks for posting. It's great to see Dom is safely behind bars...no wait, I meant it's good to see that he's doing well. Talented guy.
by dignan
Thu Dec 23, 2010 7:29 am
Forum: Natural Approach
Topic: herbals
Replies: 578
Views: 130108

Bender, the big thing going on with cannabinoid research these days is the CUPID clinical trial in the UK. They actually have a really good website:

http://sites.pcmd.ac.uk/cnrg/cupid.php

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