This Is MS Multiple Sclerosis Knowledge & Support Community

They say that they have "successfully conducted more than 7,000 stem cell procedures with less than 0.01% adverse reactions reported.” simple math reveals that 0.01% of 7000 transplants is 0.7 adverse reactions which is less than 3 adverse reactions related to this news story alone Luckily, Dr....

If you have numbness of your legs and babinski signs, your neurologist will probably recommend an MRI scan of your spine. This can be caused by various problems including MS.

Jimmy Legs is correct. It is a lesion confirmed by objective evidence such as examination, visual evoked potentials, or MRI. Lets say that you report numbness in your legs, but your examination is normal, this is subjective. However, lets say you report numbness in your legs, and you have brisk lowe...

Mr. Success: I did not intend to imply that Dr. Zamboni is a bad guy or that CCSVI is some kind of nefarious plot. The problem with having a conflict of interest is that it leads to unintentional subconscious biases. The "financial advisor" selling you a variable annuity or whole life insu...

Vesta: I appreciate your response, but the point I was trying to make is that you don't know if you would be better off. This is just speculation. Many treatments that are very popular and have significant anecdotal evidence end up being completely ineffective. A good example is blood letting which ...

1eye wrote:

awesome

MrSuccess: Zamboni has his own conflicts of interest. There is no doubt that his reputation and significant amounts of future money are tied to the outcome of this trial. No one is 100% unbiased.

-C

Had I known this years ago, I wouldn't need a cane today. How do you know? Perhaps you would be no better off. According to Dr. Sclafani, the balloon to expand the vein was too small and all MS cases (RR SP PP) were treated the same even though they are very different Someone is certainly welcome t...

Calling novantrone effective is stretching reality into "alternative facts." :roll: It is effective, but the risks of the treatment (heart failure, leukemia, infection) are often greater than the benefit, so it is no longer used. The poor side effect profile has nothing to do with the eff...

That is a valid point, but ultimately there needs to be some kind of way of determining effectiveness. And perhaps "mostly everyone" would have been a better way of stating what I meant. If around 100% is 'silly', in your opinion, what percentage would not be considered silly? It depends ...

"Most proven effective treatments do not work for everyone" Sorry, this translates {to me} that they are proven not to necessarily work. Because if they truly worked, wouldn't the treatment work for everyone? I think it is silly to say that a treatment "truly works" only if it i...

flipflopper wrote:I will recommend this popular article to everyone who has not read it. The title is self-explanatory "Why Most Published Research Findings Are False". http://journals.plos.org/plosmedicine/a ... ed.0020124 .

great article

"HSCT, alemtuzumab, rituximab, ocrelizumab, ofatumumab, daclizumab, cyclophosphamide, novantrone, natalizumab" None of these are proven to work. I know we all really want them/something to really work. But... What kind of proof would you accept? All of the treatments I mentioned have over...

I agree with Cece here. Most proven effective treatments do not work for everyone. Not everyone with acute appendicitis survives after antibiotics and surgery. Only 96% of children survive acute lymphoblastic leukemia.

The expectation for 100% efficacy is unrealistic.

A good community is a valuable thing. I have met more than 3 TiMS members in the flesh! And it was wonderful to talk in person to the people I'd been talking to online. I hope the general forum gets restored to whatever you can make it be. I hope more positive CCSVI news comes in at ISNVD because t...