This Is MS Multiple Sclerosis Knowledge & Support Community

Here is another way to help modify and restrict the bad behavior of those "ROUGE MMP-9s" that do not have an attached TIMP-1 to regulate what they should attack and cut up. Once they get an attached TIMP-1 they would be less likely to make holes in the BBB and eat myelin. Simvastatin(ZOCOR...

NEWS FLASH!!! It accumulates in BRAIN also!!! jackD Radiology. 2015 May 5 :142690. [Epub ahead of print] Gadolinium-based Contrast Agent Accumulates in the Brain Even in Subjects without Severe Renal Dysfunction: Evaluation of Autopsy Brain Specimens with Inductively Coupled Plasma Mass Spectroscop...

Yodi wrote:Cheer up, 76 sounds not that bad at all. However, priority should be given to quality of life

When you get to my age -72- you may be slightly more concerned about this negative news on MS folks dying early.

jackD

Not what I wanted to read this morning. jackD People With Multiple Sclerosis May Have Double the Risk of Dying Early May 27, 2015 MINNEAPOLIS -- May 27, 2015 -- New research suggests people with multiple sclerosis (MS) may have double the risk of dying early compared with people without MS, with tho...

I suggest you read my posting in the AVONEX section you will learn the HOW and WHY PYCNOGENOL lowers MMP-9s and does All kind of GOOD THINGS to protect Myelin. http://www.thisisms.com/forum/avonex-f5/topic4186.html http://home.ix.netcom.com/~jdalton/Yongrev.pdf Neuroscientist. 2002 Dec;8(6):586-95. ...

NEWS FLASH!!! It accumulates in BRAIN also!!! jackD Radiology. 2015 May 5 :142690. [Epub ahead of print] Gadolinium-based Contrast Agent Accumulates in the Brain Even in Subjects without Severe Renal Dysfunction: Evaluation of Autopsy Brain Specimens with Inductively Coupled Plasma Mass Spectroscopy...

Seems like Metformin does all the right things to treat MS. jackD J Immunol. 2009 Jun 15;182(12):8005-14. doi: 10.4049/jimmunol.0803563. Metformin attenuated the autoimmune disease of the central nervous system in animal models of multiple sclerosis. Nath N, Khan M, Paintlia MK, Singh I, Hoda MN, Gi...

Great summary from NIH-NLM.

JackD


http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649683/

The Corpus Callosum looks like a great place for MS to find a good feast on the nerve myelin covering.

jackD

I recently had an exchange of emails with someone who had severe TN that had an interesting good outcome. She felt her TN might be caused by MS so she contacted me. I learned that she was a vegetarian and had recently gone to a more restrictive diet. I suggested she see her GP and get a B12 shot. Sh...

the techie stuff new on pubmed ... Molecules. 2014 Dec 26;20(1):335-347. Anti-Inflammatory Effects of Vinpocetine in Atherosclerosis and Ischemic Stroke: A Review of the Literature. Zhang L1, Yang L2. Abstract Immune responses play an important role in the pathophysiology of atherosclerosis and isch...

I would like to add that I am taking some VINPOCETINE to help recover from my little stroke and to prevent future strokes. Face sagging left side gone and all other symptoms gone. My blood pressure problem has been resolved current 138/68. I have lost 25 lbs and intend to lose another 20 lbs. VINPOC...

jimmylegs wrote:re high bp - may i inquire as to your daily magnesium regimen, jack? and if you've had your serum level tested at all?

I take 3 200mg magnesium citrate daily plus the 100 mg magnesium dioxide in the cheap multivitamin.
Got my pressure down to 188/114. I am going to try some Zanaflex next.

jackD

Hi Jack, Sorry to hear that. I hope all goes well with you. What tests did they conduct regarding the stroke? Did they have a perspective on why it happened? Regards They did a cat san immediately and then two days later fallowed it with a MRI. Cause in my case it is extreme high blood pressure tha...

I have posted about this Stroke Risk in the aneurism board. The problem is those nasty MMP-9s being elevated in MS. MMp-9s like to eat the "elastin" in the artery walls. This is the rubber band stuff that allows the artery walls to flex and return back to the normal shape. If the MMP-9s e...