Gene Therapy

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Study reveals more evidence that some forms of MS are...

Last post by lyndacarol « Tue Apr 18, 2017 6:45 am
Replies: 2
by MSUK » Tue Apr 18, 2017 4:29 am

First post

Study reveals more evidence that some forms of MS are inherited

Less than a year after publishing research identifying a single genetic mutation...

Last post

I recently had my DNA tested, for ancestry reasons. To my surprise I have a higher than average Neanderthal percentage, I didn't even realize that...

2 Replies

9826 Views

Last post by lyndacarol
Tue Apr 18, 2017 6:45 am
Two gene variants directly linked to multiple sclerosis

Last post by MSUK « Fri Mar 31, 2017 5:10 am

by MSUK » Fri Mar 31, 2017 5:10 am

People with variants of two particular genes are three times more likely to develop multiple sclerosis (MS) according to findings from scientists at...

0 Replies

2478 Views

Last post by MSUK
Fri Mar 31, 2017 5:10 am
A mutation increases 70% the risk of multiple sclerosis!

Last post by frodo « Thu Jun 16, 2016 12:51 am
Replies: 3
by ton » Wed Jun 01, 2016 11:19 am

First post

This is the first genetic alteration associated with less frequent familial cases.

A mutation in the gene NR1H3 increases by 70% the risk of...

Last post

Where does the article state that the gene NR1H3 increases by 70% the risk of developing MS?

I think it was a misquote. What they say is that...

3 Replies

4509 Views

Last post by frodo
Thu Jun 16, 2016 12:51 am
New gene being linked to multiple sclerosis

Last post by MSUK « Tue May 31, 2016 1:51 am

by MSUK » Tue May 31, 2016 1:51 am

Researchers have discovered a gene involved in deregulation of certain immune cells in multiple sclerosis...Read more -

0 Replies

2803 Views

Last post by MSUK
Tue May 31, 2016 1:51 am
Gene expression between men and women differs during relapse

Last post by MSUK « Mon Feb 15, 2016 5:35 am

by MSUK » Mon Feb 15, 2016 5:35 am

Gene expression between men and women differs during relapse and remission in MS

A new study in Spain has highlighted differing patterns of small...

0 Replies

3212 Views

Last post by MSUK
Mon Feb 15, 2016 5:35 am
MS resistance traced to a gene variant in Colombia

Last post by MSUK « Fri Jan 22, 2016 5:26 am

by MSUK » Fri Jan 22, 2016 5:26 am

A Colombian study has reported finding an increased risk of multiple sclerosis (MS) associated with a particular allele, or gene variant, in a group...

0 Replies

3045 Views

Last post by MSUK
Fri Jan 22, 2016 5:26 am
Discovering a ‘new world’ in MS through Genomics

Last post by MSUK « Mon Oct 12, 2015 1:31 am

by MSUK » Mon Oct 12, 2015 1:31 am

A Satellite Symposia entitled Discovering A New World in MS supported by Teva Neuroscience has been held at the 31st Congress of the European...

0 Replies

3415 Views

Last post by MSUK
Mon Oct 12, 2015 1:31 am
New genetic risk factors identified

Last post by MSUK « Thu Sep 10, 2015 12:41 am

by MSUK » Thu Sep 10, 2015 12:41 am

Two new risk factors for multiple sclerosis have been identified by a research group at the Wellcome Trust Centre for Human Genetics at the...

0 Replies

3382 Views

Last post by MSUK
Thu Sep 10, 2015 12:41 am
Identifying MS gene mutations could lead to personalised....

Last post by MSUK « Fri Jul 24, 2015 5:59 am

by MSUK » Fri Jul 24, 2015 5:59 am

Identifying MS gene mutations could lead to personalised treatments

Personalised medicine, often applied to treat cancer, may be possible for...

0 Replies

3620 Views

Last post by MSUK
Fri Jul 24, 2015 5:59 am
Gene that "triggers" multiple sclerosis identified

Last post by MSUK « Thu Jun 18, 2015 1:01 am

by MSUK » Thu Jun 18, 2015 1:01 am

New research identifies a pivotal gene in multiple sclerosis, linking it to the most important genetic factor that drives the condition..... Read...

0 Replies

3574 Views

Last post by MSUK
Thu Jun 18, 2015 1:01 am
Researcher improves methodology ......

Last post by MSUK « Tue Jun 16, 2015 1:14 am

by MSUK » Tue Jun 16, 2015 1:14 am

Researcher improves methodology for predicting genetic ‘mutations’

Researchers around the world have sequenced the genomes of patients living with...

0 Replies

3188 Views

Last post by MSUK
Tue Jun 16, 2015 1:14 am
Gene linked to interferon-beta treatment

Last post by MSUK « Mon May 18, 2015 12:36 am

by MSUK » Mon May 18, 2015 12:36 am

A new study led by investigators at Brigham and Womens Hospital (BWH) reports the discovery of a genetic variant associated with a patients...

0 Replies

3458 Views

Last post by MSUK
Mon May 18, 2015 12:36 am
Genetic risk factor uncovered

Last post by MSUK « Thu Mar 05, 2015 1:21 am

by MSUK » Thu Mar 05, 2015 1:21 am

Researchers at the University of Illinois at Chicago have identified a genetic variation that in women significantly increases their risk of...

0 Replies

3575 Views

Last post by MSUK
Thu Mar 05, 2015 1:21 am
MS? Immune system or nervous system?

Last post by MSUK « Fri Nov 14, 2014 1:54 am

by MSUK » Fri Nov 14, 2014 1:54 am

Does multiple sclerosis stem from immune system and not the nervous system?

The genetic starting point for autoimmune diseases like multiple...

0 Replies

3642 Views

Last post by MSUK
Fri Nov 14, 2014 1:54 am
New DNA software may improve MS diagnosis and treatment

Last post by MSUK « Fri Oct 31, 2014 1:08 am

by MSUK » Fri Oct 31, 2014 1:08 am

Researchers from UC San Francisco, the Broad Institute of MIT and Harvard, and Yale School of Medicine recently developed a software tool that helps...

0 Replies

3586 Views

Last post by MSUK
Fri Oct 31, 2014 1:08 am
New gene variants may relate to MS susceptibility

Last post by kengriff « Sun Oct 05, 2014 10:43 pm
Replies: 1
by MSUK » Fri Oct 03, 2014 6:18 am

First post

Approximately 110 multiple genetic variations were previously identified by genome-wide association studies (GWAS) to be associated with Multiple...

Last post

Gene is the most important building block of our body .I am a student of Genetic Engineering and I know the variants of genes. And I am really very...

1 Replies

3657 Views

Last post by kengriff
Sun Oct 05, 2014 10:43 pm
Gene involvement in mechanisms of neurodegeneration.....

Last post by MSUK « Thu Aug 21, 2014 2:42 am

by MSUK » Thu Aug 21, 2014 2:42 am

Gene involvement in mechanisms of neurodegeneration and neuroinflammation

Common mechanisms in neurodegeneration and neuroinflammation: a BrainNet...

0 Replies

3533 Views

Last post by MSUK
Thu Aug 21, 2014 2:42 am
Nerve conduction velocity gene linked to multiple sclerosis

Last post by CureOrBust « Wed Aug 13, 2014 3:33 am
Replies: 1
by MSUK » Wed Aug 13, 2014 12:21 am

First post

Evidence found in both human multiple sclerosis patients and experimental mouse models, according to research published in the American Journal of...

Last post

Scientists said S1PR2 could work by helping to make the blood-brain barrier, in charge of stopping potentially harmful substances from entering the...

1 Replies

3839 Views

Last post by CureOrBust
Wed Aug 13, 2014 3:33 am
Multiple sclerosis discovery may explain gender gap

Last post by MSUK « Fri May 09, 2014 1:07 am

by MSUK » Fri May 09, 2014 1:07 am

A key difference in the brains of male and female MS patients may explain why more women than men get the disease, a study suggests.

Scientists at...

0 Replies

5762 Views

Last post by MSUK
Fri May 09, 2014 1:07 am
Genome study identifies three possible drug candidates...

Last post by CureOrBust « Fri May 02, 2014 6:31 pm
Replies: 1
by MSUK » Fri May 02, 2014 5:15 am

First post

Genome study identifies three possible drug candidates for autoimmune diseases

New pharmaceuticals to fight autoimmune diseases, such as multiple...

Last post

Genome study identifies three possible drug candidates for autoimmune diseases

... the scientists combined drug screening with state-of-the-art...

1 Replies

3836 Views

Last post by CureOrBust
Fri May 02, 2014 6:31 pm
Researchers testing gene therapy to thwart effects of MS

Last post by MSUK « Wed Apr 09, 2014 7:41 am

by MSUK » Wed Apr 09, 2014 7:41 am

In patients with multiple sclerosis, the body turns on itself, launching an immune system attack that destroys the coating around nerve fibers in the...

0 Replies

4282 Views

Last post by MSUK
Wed Apr 09, 2014 7:41 am
Positive clinical performance of MSPrecise

Last post by MSUK « Mon Jan 27, 2014 7:05 am

by MSUK » Mon Jan 27, 2014 7:05 am

DioGenix reports positive clinical performance of molecular diagnostic MSPrecise for Multiple Sclerosis

DioGenix, Inc. announced today new data...

0 Replies

3833 Views

Last post by MSUK
Mon Jan 27, 2014 7:05 am
Researchers assess familial risks for MS ......

Last post by MSUK « Wed Jan 22, 2014 6:09 am

by MSUK » Wed Jan 22, 2014 6:09 am

Researchers assess familial risks for MS using population registers, health care registries

Even though multiple sclerosis is largely caused by...

0 Replies

3631 Views

Last post by MSUK
Wed Jan 22, 2014 6:09 am
MS research appeal

Last post by MSUK « Wed Jan 22, 2014 3:46 am

by MSUK » Wed Jan 22, 2014 3:46 am

An Orcadian geneticist who is researching the causes of MS in the Northern Isles, is asking people in Orkney to help create a list of all the people...

0 Replies

3572 Views

Last post by MSUK
Wed Jan 22, 2014 3:46 am
Mapping reveals 110 multiple sclerosis risk genes

Last post by MSUK « Fri Jan 10, 2014 2:14 am

by MSUK » Fri Jan 10, 2014 2:14 am

Norwegian researchers have mapped genetic variations associated with an increased risk of multiple sclerosis (MS) and myasthenia gravis (MG),...

0 Replies

3715 Views

Last post by MSUK
Fri Jan 10, 2014 2:14 am
Genetic breakthrough brings scientists closer to M.S. cure

Last post by vesta « Wed Dec 18, 2013 10:11 am
Replies: 1
by seeva » Tue Nov 19, 2013 1:29 am

First post

A DR. DAVID BOOTH FROM WESTMEAD GENTIC STUDIES FINDS VERY CLOSE TO IDENTIFIED THE GENES ASSOSIATED WITH M.S MORE DETAILS FROM THE WEB SITE
REGARDS...

Last post

Overlap with Crohn's and coeliac disease equals gluten intolerance.

Regards, Vesta

1 Replies

11848 Views

Last post by vesta
Wed Dec 18, 2013 10:11 am
Genetic clues to what triggers Multiple Sclerosis

Last post by Quest56 « Tue Oct 01, 2013 11:58 am
Replies: 2
by MSUK » Wed Aug 10, 2011 10:00 pm

First post

Around 30 genetic risk factors for developing multiple sclerosis have been discovered by a UK-led team.

It brings to more than 50 the total number...

Last post

In today's Science Digest: 48 new genetic variants associated with MS.

2 Replies

7747 Views

Last post by Quest56
Tue Oct 01, 2013 11:58 am
New genetic study may help unravel multiple sclerosis

Last post by MSUK « Mon Sep 30, 2013 1:11 am

by MSUK » Mon Sep 30, 2013 1:11 am

A major milestone has been reached on the path to finding a cure for multiple sclerosis (MS), researchers say.

A group of international scientists,...

0 Replies

4367 Views

Last post by MSUK
Mon Sep 30, 2013 1:11 am
does ms run in families

Last post by brent « Sun Sep 15, 2013 11:27 pm
Replies: 10
by baffled » Sat Jan 14, 2012 2:17 pm

First post

I was really interested to hear there could be a gene that identifies the risk of ms, i have ms with four aunties ( mum's sister's ) and 2 cousins...

Last post

As far as I know some distant cousin of mine has ms. Is there any new research on whether or not ms has a genetic component?

10 Replies

6887 Views

Last post by brent
Sun Sep 15, 2013 11:27 pm
Study to investigate the human genome in MS announced

Last post by MSUK « Wed Sep 04, 2013 1:50 am

by MSUK » Wed Sep 04, 2013 1:50 am

The National Institutes of Health (NIH) awarded Benaroya Research Institute at Virginia Mason (BRI) a $1.9 million grant to find marks in the human...

0 Replies

3824 Views

Last post by MSUK
Wed Sep 04, 2013 1:50 am
Unraveling complex genetic interplay for MS risks

Last post by MSUK « Mon Jul 15, 2013 12:01 am

by MSUK » Mon Jul 15, 2013 12:01 am

A Western Australia-cohort of patients has been used to study the risk modifying role of specific genes suspected to contribute to one’s...

0 Replies

4003 Views

Last post by MSUK
Mon Jul 15, 2013 12:01 am
Absence of gene leads to earlier, more severe case of MS

Last post by MSUK « Tue Jun 25, 2013 1:45 am

by MSUK » Tue Jun 25, 2013 1:45 am

A UC San Francisco-led research team has identified the likely genetic mechanism that causes some patients with multiple sclerosis (MS) to progress...

0 Replies

3978 Views

Last post by MSUK
Tue Jun 25, 2013 1:45 am
Casting light on multiple sclerosis heterogeneity.....

Last post by MSUK « Mon Mar 18, 2013 2:39 am

by MSUK » Mon Mar 18, 2013 2:39 am

Casting light on multiple sclerosis heterogeneity: the role of HLA-DRB1 on spinal cord pathology

Clinical heterogeneity in multiple sclerosis is the...

0 Replies

4634 Views

Last post by MSUK
Mon Mar 18, 2013 2:39 am
Assessing interactions between HLA-DRB1*15 and Epstein-Barr

Last post by MSUK « Wed Feb 20, 2013 1:40 am

by MSUK » Wed Feb 20, 2013 1:40 am

Assessing interactions between HLA-DRB1*15 and infectious mononucleosis on the risk of multiple sclerosis

Summary: This study from the UK looked at...

0 Replies

4287 Views

Last post by MSUK
Wed Feb 20, 2013 1:40 am
Genetic and infectious profiles of Japanese MS patients

Last post by vesta « Fri Nov 30, 2012 3:51 am
Replies: 1
by MSUK » Wed Nov 14, 2012 12:52 am

First post

Abstract

Background
Nationwide surveys conducted in Japan over the past thirty years have revealed a four-fold increase in the estimated number of...

Last post

Maybe change in diet accounts for the increased incidence of MS. The traditional Japanese diet based on rice, fish and vegetables protects, the...

1 Replies

5106 Views

Last post by vesta
Fri Nov 30, 2012 3:51 am
Scientists deepen genetic understanding of MS

Last post by MSUK « Thu Oct 25, 2012 11:21 pm

by MSUK » Thu Oct 25, 2012 11:21 pm

Five scientists, including two from Simon Fraser University, have discovered that 30 per cent of our likelihood of developing Multiple Sclerosis (MS)...

0 Replies

6281 Views

Last post by MSUK
Thu Oct 25, 2012 11:21 pm
Gene could be used to treat Multiple Sclerosis

Last post by MSUK « Mon Oct 08, 2012 8:03 am

by MSUK » Mon Oct 08, 2012 8:03 am

New treatments for multiple sclerosis (MS) and other auto-immune diseases could flow from an important discovery made by scientists at NUI Maynooth....

0 Replies

5450 Views

Last post by MSUK
Mon Oct 08, 2012 8:03 am
Transcription profile distinguishes subgroups in MS

Last post by MSUK « Wed Sep 26, 2012 11:13 pm

by MSUK » Wed Sep 26, 2012 11:13 pm

Patients with multiple sclerosis (MS) can be differentiated according to their transcription profile, according to a study published in the Sept. 26...

0 Replies

4109 Views

Last post by MSUK
Wed Sep 26, 2012 11:13 pm
Clues to causes of nerve cell degeneration

Last post by MSUK « Wed Jan 11, 2012 2:08 am

by MSUK » Wed Jan 11, 2012 2:08 am

Clues to causes of nerve cell degeneration provided by spasticity gene finding

The discovery of a gene that causes a form of hereditary spastic...

0 Replies

5667 Views

Last post by MSUK
Wed Jan 11, 2012 2:08 am
Three novel Multiple Sclerosis susceptibility loci identifie

Last post by MSUK « Mon Jan 09, 2012 12:26 am

by MSUK » Mon Jan 09, 2012 12:26 am

Three novel multiple sclerosis (MS) genetic susceptibility loci have been identified, according to a meta-analysis published in the December issue of...

0 Replies

5060 Views

Last post by MSUK
Mon Jan 09, 2012 12:26 am
Right acting/right thinking TIMP-1 gene transfer

Last post by jackD « Sat Dec 03, 2011 8:51 pm

by jackD » Sat Dec 03, 2011 8:51 pm

Right acting/right thinking TIMP-1 gene transfer?

Regarding the concept of MMP-9s being responsible for most myelin damage, I must confess that I...

0 Replies

4544 Views

Last post by jackD
Sat Dec 03, 2011 8:51 pm
HLA-DRB1*15:01 and multiple sclerosis: a female association?

Last post by MSUK « Wed Nov 30, 2011 2:45 am

by MSUK » Wed Nov 30, 2011 2:45 am

Abstract

Background: The association between multiple sclerosis (MS) and the HLA-DRB1*15:01 haplotype has been proven to be strong, but its...

0 Replies

5219 Views

Last post by MSUK
Wed Nov 30, 2011 2:45 am
genetic counselor says......

Last post by coach « Fri Jul 22, 2011 11:42 am
Replies: 5
by Mike56 » Sat Dec 05, 2009 9:14 am

First post

An intersting comment by my UBC MS clinic geneticist 80% of those with MS have no relatives with MS, 20% have another relative with MS, and it's very...

Last post

I have MS and have had it for 27 years, 14 which were asymootomatic. Started after the birth of my first child with a case of optic neuritis. My...

5 Replies

8332 Views

Last post by coach
Fri Jul 22, 2011 11:42 am
MS gene revealed by chance

Last post by scorpion « Fri Sep 17, 2010 9:37 am

by scorpion » Fri Sep 17, 2010 9:37 am

0 Replies

5276 Views

Last post by scorpion
Fri Sep 17, 2010 9:37 am
gene predicts severity of ms?

Last post by scorpion « Tue Aug 03, 2010 6:33 pm

by scorpion » Tue Aug 03, 2010 6:33 pm

0 Replies

5003 Views

Last post by scorpion
Tue Aug 03, 2010 6:33 pm
gene called ZFP191

Last post by scorpion « Tue Jan 19, 2010 3:19 pm

by scorpion » Tue Jan 19, 2010 3:19 pm

0 Replies

5267 Views

Last post by scorpion
Tue Jan 19, 2010 3:19 pm
Biomarker May Have Potential to Help With Diagnosis, Treatme

Last post by scorpion « Mon Oct 19, 2009 2:02 pm

by scorpion » Mon Oct 19, 2009 2:02 pm

0 Replies

5019 Views

Last post by scorpion
Mon Oct 19, 2009 2:02 pm
Epigenetics

Last post by dignan « Fri Oct 02, 2009 10:10 am
Replies: 4
by LR1234 » Thu Oct 01, 2009 1:46 pm

First post

Hi,
I just watched a really interesting programme about identical twins with the same genetics/DNA etc. The programme was about epigenetics and how...

Last post

Yeah, the CCVI angle is interesting. From what I understand from the conference Cheer attended, people are born with stenosis, but that isn't to say...

4 Replies

5526 Views

Last post by dignan
Fri Oct 02, 2009 10:10 am
Researchers Identify Two Genes as Potential Therapeutic Targ

Last post by scorpion « Fri Sep 11, 2009 3:43 pm

by scorpion » Fri Sep 11, 2009 3:43 pm

Researchers Identify Two Genes as Potential Therapeutic Targets for Multiple
Sclerosis

ROCHESTER, Minn., Sept. 11 /PRNewswire-USNewswire/ -- A...

0 Replies

4972 Views

Last post by scorpion
Fri Sep 11, 2009 3:43 pm
Inherited illness gene swap hope

Last post by scorpion « Mon Sep 07, 2009 10:37 am

by scorpion » Mon Sep 07, 2009 10:37 am

*
*

27/08/2009

Diseases past down the generations could be wiped out with a breakthrough IVF gene swap.

Scientists created healthy infant monkeys...

0 Replies

5273 Views

Last post by scorpion
Mon Sep 07, 2009 10:37 am

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