Dalfampridine, or Ampyra, is a potassium channel blocker that is shown to improve visual function, motor skills and relieve fatigue in MS patients.
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Last post by NHE
Sat Jul 16, 2016 11:38 pm
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Ampyra, 4-AP, 4-AP-3-MeOH
Replies: 4
by
jennyms » Fri Dec 27, 2019 10:51 pm
First post
Hello everybody.
It's my first post here, I have only recently discovered this site, and I have to say, it is a Godsend. I’ve been reading through...
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Acrolein-mediated conduction loss is partially restored by K⁺ channel blockers.
J Neurophysiol. 2016 Feb 1;115(2):701-10.
Acrolein-mediated...
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Last post by NHE
Tue Dec 31, 2019 9:54 pm
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Would like to hear from people using Ampyra
Replies: 22
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suze » Fri Sep 07, 2012 7:24 pm
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Reply to topic in 'general' section:
I have been using it for about 2 months. It's definitely not a wonder drug. I'm really not sure if I am walking...
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I ve been taking Ampyra (2*10 mg per day) for 6 years.
I ve never felt good or bad effects while on it.
However, today, I forgot to take my 5pm...
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Last post by zen2010
Sun Sep 01, 2019 5:23 pm
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generic dalfampridine
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nellie » Fri Oct 12, 2018 8:02 am
Does anyone know if the generic ampyra can be purchased yet in the US. I read where Mylan has brought it to the market this month.
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Last post by nellie
Fri Oct 12, 2018 8:02 am
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Last post by Petr75
Wed Sep 12, 2018 6:23 am
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Dalfampridine may worsen pre-existing trigeminal neuralgia..
Replies: 1
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MSUK » Wed Oct 25, 2017 8:00 am
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Dalfampridine may worsen pre-existing trigeminal neuralgia in MS patients #ECTRIMS
A study that set out to discover whether trigeminal neuralgia...
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Dalfampridine: old bird poison helps MS patients walking..
In Annels of neurology an editorial on 4-Aminopyridine: New Life For an Old Drug....
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Last post by THX1138
Thu Oct 26, 2017 12:54 pm
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Biogen’s MS drug for improving walking gets the green light
Replies: 2
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MSUK » Fri May 26, 2017 12:36 am
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A drug, proven to improve walking in people with MS, has been approved and given standard marketing authorisation by the European Commission...
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Side effects?
Hi Sean,
You can check the Prescribing Information for a discussion of Ampyra's side effects.
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Last post by NHE
Mon May 29, 2017 8:42 pm
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Modified ampyra dosage??
Replies: 4
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Grumpster » Wed May 03, 2017 4:01 pm
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Has anyone done any modifications to the dosage/frequency for this drug? I had what seemed to be substantial benefit from this drug within 3 days or...
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Thanks Moragh,
I think I may need to try something like that after discussing with my neuro. Otherwise I may just stop taking it since I do not seem...
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Last post by Grumpster
Mon May 22, 2017 10:51 am
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NYC Compound pharmacists who provides 4-AP
Replies: 2
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Algis » Wed Nov 11, 2015 3:26 am
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As few of you knows; I'm living in Asia and can't get a hand on many medicines over here.
I have a friend traveling to NYC shortly and she would...
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Be very cautious of compounded 4-AP. It is very sensitive to exposure to air, so if the pharmacy does not store it correctly, it will lose its...
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Last post by CureOrBust
Sat Apr 09, 2016 4:52 pm
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Ampyra Vs Compounded 4-AP?
Replies: 10
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CureOrBust » Mon Oct 24, 2011 4:01 am
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Has anyone tried both? and therefore could give their opinion on the differences? /:)
I know for me I think I paid $65 for 100 10mg tablets of...
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Do you read more about 4-AP-3-MeOH up to now?
It should be 10 times more powerful than 4-AP. By 10x more powerful , they only appear to mean that the...
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Last post by UWE59
Fri Oct 02, 2015 7:00 am
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Last post by UWE59
Thu Oct 01, 2015 12:40 pm
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RE AMPYRA WITH LDN
Replies: 4
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seeva » Thu Nov 24, 2011 2:15 am
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Hi, to the forum:
Has anyone been thinking of taking both AMPYRA( 4-AP) and LDN?
Does anyone know if there are contraindications?
What a dilemma*
I...
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I take both and experienced no issues.
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Last post by AnnieG
Fri Jul 24, 2015 8:19 am
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Ampyra Seizures anyone?
Replies: 4
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Grumpster » Tue Feb 24, 2015 3:27 pm
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I tried searching the forum, but that did not work out. Has anyone experienced seizures from taking ampyra? That scares the wits out of me. If you...
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I have been using aminopyridine (4) for almost 6 years. I think its the same thing. like the benefits it provides. I have never had a seizure. Kidney...
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Last post by Moragh
Wed Feb 25, 2015 5:16 pm
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Hesitant to start Ampyra
Replies: 2
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Grumpster » Mon Jan 26, 2015 4:15 pm
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I am on the fence regarding starting Ampyra. I have a 60 day trial sitting at home. I am scared of the possible seizures. I have no kidney disorder...
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Thanks Eileen,
I got it through the manufacturer. I spoke with their Dr. about my concerns. They say it is a low percentage, but ~2% is actually...
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Last post by Grumpster
Wed Feb 11, 2015 3:40 pm
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Source for 4-aminopyridine
Replies: 1
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Jemwed » Tue Dec 09, 2014 4:03 pm
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Ampyra and 4-ap are out of the question here in Japan.
I'm forced to order my own and compound it myself.
Does anyone know of a good source?...
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In Australia, I used the following company to supply 4-AP-3-MeHO (NB: It did nothing for me compared to 4-AP). I got their name from the published...
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Last post by CureOrBust
Tue Dec 09, 2014 7:55 pm
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Last post by MSUK
Wed Nov 19, 2014 5:41 am
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Last post by MSUK
Thu Oct 30, 2014 12:56 am
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Last post by Quest56
Tue Sep 30, 2014 7:21 am
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Last post by MSUK
Tue Jun 17, 2014 1:07 am
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Last post by MSUK
Tue May 27, 2014 2:48 am
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Last post by CureOrBust
Sat May 17, 2014 6:07 pm
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Fampyra, any other benefits
Replies: 3
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gymbuff » Sat Aug 20, 2011 12:33 am
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Hi all,
I was wondering if there are any other benefits associated with Fampyra other than improved walking speed. I am not particlarly concerned...
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I started using Ampyra 3.5 years ago. I didn't think it helped so I went off it. Then I realized how much it helped because my stamina took a...
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Last post by blavery
Tue May 06, 2014 6:59 am
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Natural alternative/substitute to ampyra
Replies: 4
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gymbuff » Tue Nov 27, 2012 1:27 am
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Hi all
I was just wondering is there any natural/homeopathic alternative to ampyra showing reasonable results. Any supplements etc. that have a...
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Magnesium is natural potassium channel blocker.
Unlike Ampyra, which is a sustained-release version of a potassium channel blocking bird poison...
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Last post by THX1138
Tue Apr 29, 2014 12:45 am
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Too expensive
Replies: 8
by
David1949 » Wed Oct 09, 2013 8:07 am
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Well I was about to receive a 30 day supply of Ampyra. But when the pharmacy informed me of the cost, I cancelled it. I have a high deductible in my...
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I will be losing my private insurance & will be going with a plan where medicare d is used for prescriptions. They have terrible coverage for ampyra....
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Last post by Quest56
Wed Mar 26, 2014 12:40 pm
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Fampyra® now available in Ireland to treat MS walking
Replies: 1
by
MSUK » Wed Jan 15, 2014 3:07 am
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Fampyra® now available in Ireland to treat MS walking impairment
Biogen Idec today announced that Fampyra® (prolonged-release fampridine tablets)...
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Fampyra® is a potassium channel blocker.
Magnesium also blocks potassium channels, but as an essential nutrient, it is used by the body for a...
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Last post by THX1138
Wed Jan 15, 2014 11:05 am
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Approval for Fampyra in Australia
Replies: 6
by
MSUK » Mon May 16, 2011 12:41 am
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The Australian Therapeutic Goods Administration (TGA) has granted approval for Fampyra™, (fampridine) 10 mg Modified Release (MR) tablet, for the...
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I get it compounded in 10mg capsules, 100 for about $60
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Last post by CureOrBust
Tue Oct 29, 2013 2:59 am
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Need Ampyra Advice
Replies: 3
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Loriyas » Wed Oct 09, 2013 10:30 am
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I am torn. My left leg is weaker than my right and always have been. I have been working out faithfully and it remains the same. Although both legs...
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4-AP is not stable, and all the packaging of Ampyra confirms this to be the case. A 1 year old case is not what I would base any decision on anyway.
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Last post by CureOrBust
Thu Oct 10, 2013 3:24 am
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Fampyra and 4-AP
Replies: 1
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UWE59 » Sat Jun 08, 2013 4:29 am
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I tried Fampyra for two weeks with no clear reaktion in walking improvement. (MS since 23 years, EDSS 6,5)
I made a break for 3 days (no significant...
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They are the same active chemical with Fampyra being a proprietary slow release version. Taking both would be the equivalent of double dosing.
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Last post by CureOrBust
Sat Jun 08, 2013 3:39 pm
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No added benefit proven for Fampiridine in MS
Replies: 5
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MSUK » Sun Sep 02, 2012 11:58 pm
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Drug manufacturer did not present evaluable study data on the appropriate comparator therapy
Fampridine (trade name Fampyra®) has been approved in...
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Hi All,
Just to correct my original post. I have been taking Fampyra since last December - which is closer to 6 months than 3 months.
Anyway as I...
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Last post by gymbuff
Mon May 27, 2013 11:55 pm
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Vision Improvements with Ampyra?
Replies: 2
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Loony03 » Tue Jan 08, 2013 6:25 pm
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Is there anyone here with optic neuritis who has noticed any vision improvements after taking Ampyra? I was dx with MS about 5 years ago after going...
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Thanks for your input. I'm going to ask about a prescription in hopes that my insurance will cover it. The possible side effects (mainly seizures) do...
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Last post by Loony03
Thu Jan 10, 2013 9:19 am
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Last post by MSUK
Wed Oct 10, 2012 11:14 am
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Last post by suze
Thu Sep 27, 2012 12:46 am
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Acorda's Ampyra fails main goal of post-marketing study
Replies: 3
by
Thomas » Mon Aug 13, 2012 5:04 am
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Acorda's Ampyra fails main goal of post-marketing study
Mon Aug 13, 2012 7:39am EDT
(Reuters) - Acorda Therapeutics Inc said a post-marketing study...
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I had the same result as Cure or Bust. Did not have increased walking speed, but my legs Much stronger ie if I was on the floor, could not get up,...
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Last post by Tracker
Sat Aug 18, 2012 5:37 pm
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Last post by MSUK
Mon Jul 23, 2012 11:23 pm
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Last post by milesap
Fri Jul 13, 2012 12:10 pm
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Ampyra - 2+ years and working great
Replies: 3
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LetsGoMarauders » Tue Jul 10, 2012 6:31 pm
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My wife has been taking Ampyra for 2+ years now and so far it's working great with her balance and coordination.
No side effects. Was taking it in...
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Even if it allows the taker to exercise a bit more and hopefully increase mobility, it would be good value.
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Last post by suze
Thu Jul 12, 2012 12:07 am
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Can you still get compounded 4-AP with Fampyra approved?
Replies: 1
by
KateCW » Mon Jun 04, 2012 11:20 am
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Those of you in the USA may know more---are pharmacies allowed to continue co mpounding this. Here in Canada my pharmacist wasn't sure, as Fampyra...
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The key ingredient in Fampyra is 4-AP, a non-patented chemical, so yes, your pharmacy should be legally able to continue to supply it. I tried...
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Last post by CureOrBust
Tue Jun 05, 2012 5:14 am
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Last post by MSUK
Thu Apr 26, 2012 1:14 am
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Last post by MSUK
Wed Apr 11, 2012 7:29 am
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Last post by MSUK
Tue Apr 03, 2012 12:11 am
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RE FREE AMPYRA FROM BIOGEN
Replies: 3
by
seeva » Thu Mar 15, 2012 10:50 pm
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DEAR FRIENDS . my name is seeva from AUSTRALIA, There is a good news for m.s patients from BIOGEN AUSTRALIA. From last week BIOGIN AUSTRALIA...
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Thanks for your mail sorry to hear that you had fall. my friend and me only one M.S medications are taking last 7 years which is LDN 3mg. while you...
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Last post by seeva
Sat Mar 17, 2012 8:02 pm
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RE FREE FAMPYRA FROM BIOGEN AUSTRALIA
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seeva » Wed Mar 14, 2012 4:27 am
HI friend my name is seeva from SYDNEY AUSTRALIA. There is a good news for m.s patients from BIOGEN AUSTRALIA. From last week BIOGIN AUSTRALIA...
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Last post by seeva
Wed Mar 14, 2012 4:27 am
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Private health coverage for ampyra in Australia?
Replies: 1
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twintwin » Sat Jan 28, 2012 4:00 am
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I have been taking ampyra (called fampyra in Australia) since it has been available in this country in October 2011. It is costly and I have been...
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My neuro says it may be considered to be put on the list this year.
Can you tell me how you find it and how much do you currently pay?
I have bad...
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Last post by riceyd
Sun Jan 29, 2012 9:00 pm
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Fampyra launched in the UK to aid MS walking
Replies: 3
by
MSUK » Thu Nov 03, 2011 10:27 pm
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Fampyra (fampridine) is indicated for use in multiple sclerosis to improve walking in patients who have a walking disability (EDSS 4-7)....
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Hi TwiNTwin. Good to hear from you. FYI all side effects have now disappeared thank goodness. I am now taking 2 x 10mg daily as I could not tolerate...
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Last post by LSITC
Sat Jan 28, 2012 3:57 am
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Ampyra? Don't think I need it?
Replies: 7
by
Bubba » Fri Dec 16, 2011 3:20 pm
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Everytime I go to my Neuro, they test my walking time.
I don't feel like I have slowed at all. But he wants me to start taking this stuff. They...
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Walking normally again is sadly something I can't remember doing anymore
I often feel the same way at times, though sometimes my brain will torture...
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Last post by CureOrBust
Tue Dec 27, 2011 5:26 pm
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Anthem Blue Cross
Replies: 2
by
Just_Me » Wed Dec 07, 2011 11:37 am
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Anybody have Anthem PPO who is taking Ampyra? How much is it costing you?
Id like to give it a try but I can't get an answer of how much it will...
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you can ableto buy 48tablets for $590.. from a eparmacy in victoria in online
regards
seeva :roll:
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Last post by seeva
Thu Dec 08, 2011 9:06 am
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hi need help
Replies: 8
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seeva » Fri Oct 14, 2011 3:35 am
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Hi friends can anyone help me regarding LDN and AMPYRA. i am about to start the new medications compunded AMPYRA from next week.sametime i am taking...
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were you by any chance Ned in a previous incarnation? :-??
I previously had Aimspro imported under the SAS scheme in Australia, I didn't realise...
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Last post by CureOrBust
Wed Nov 02, 2011 2:23 am
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Ampyra ® - improvement of patient-reported walking ability
Replies: 1
by
MSUK » Mon Jun 06, 2011 4:19 am
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Acorda Therapeutics, Inc. announced an analysis of pooled clinical trial results showed patients who were responders to Ampyra® (dalfampridine)...
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... Ampyra® (dalfampridine) Extended Release Tablets, 10 mg demonstrated clinically relevant improvements in walking ability as measured by patient...
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Last post by CureOrBust
Mon Oct 24, 2011 3:57 am
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RE:ELAINE DELACK POKARIN FOR M.S
Replies: 1
by
seeva » Mon Oct 17, 2011 12:53 pm
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Hi friends is anybody living in SYDNEY and take ELAINE DELACK POKARIN. I wold be very greateful if someone can let me know how good this drug for m.s...
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I recently forwarded you the contact details of someone in Sydney (Miranda) that has Compounded 4-AP for me. This same chemist has also compounded...
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Last post by CureOrBust
Wed Oct 19, 2011 1:17 am
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Script process
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ssmme » Thu Sep 29, 2011 7:37 am
My neuro suggested I try Ampyra and started the prescription process which is a real ordeal. I have to wait for a phone call, then call the...
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Last post by ssmme
Thu Sep 29, 2011 7:37 am
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